Aktywnosc aldolazy oraz dehydrogenazy glutaminianowej w surowicy i watrobie szczurow w czasie zaburzonego odplywu chlonki z tego narzadu

• Autorzy: Beck B , Karpe J. , Krolak-Olejnik B. , Ciszek M. , Arendt J. , Krol W.

Warianty tytułu

EN

Aldolase and glutamate dehydrogenase activity in the serum and liver of rats during disturbed lymph flow

• Języki publikacji: PL

Abstrakty

EN

Liver fibrosis plays a pivotal role in liver function impairment. Hepatic fibrosis is a complex process that involves changes in the amounts of extracellular matrix components, activation of cells capable of producing matrix materials, cytokin release, and tissue remodelling. Chronic disturbed lymph flow from the liver induced fibrosis in this organ has been described. Little is know about the alteration of metabolic pathways of the liver tissue during disturbed lymph flow. Activities of liver enzymes, aldolase and glutamate dehydrogenase were studied in serum and in the liver during disturbed lymph flow from the liver in Wistar rats.

Słowa kluczowe

PL

dehydrogenaza glutaminianowa; surowica krwi; szczury; aldolaza; aktywnosc enzymatyczna; enzymy; choroby watroby; zaburzenia odplywu limfy; homogenaty watroby

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2007
• Tom: 63
• Numer: 05
• Opis fizyczny: s.604-608,tab.,bibliogr.

Twórcy

autor

Beck B

• Slaska Akademia Medyczna, ul.Jordana 19, 41-808 Zabrze

autor

Karpe J.

autor

Krolak-Olejnik B.

autor

Ciszek M.

autor

Arendt J.

autor

Krol W.

Bibliografia

• 1.Bańkowski E.: Biochemia. Wydawnictwo Medyczne Urban&Partner, Wrocław 2004.
• 2.Beck B.: Współczesne poglądy na proces włóknienia wątroby. Diagn. Lab. 2005, 41, 95-106.
• 3.Beck B., Ciszek M., Grzybek H.: Effect of disturbed lymph flow from a liver of rats on the morphological liver structure (light and electron microscopic observation) and Transforming Growth Factor-beta1 concentration in serum. Eur. J. Clin. Invest. 2004, 34 (Suppl. 1), 44, 12.
• 4.Beck B., Ciszek M., Karpe J., Duliban H., Rajca-Biernacka I., Król W.: Correlation between TGF-beta1 and IFN-gamma concentration in serum during disturbed lymph flow from a liver of rats. E&C Hepatol. 2005, 1, 100-104.
• 5.Beck B., Ciszek M., Kosiewicz J., Duliban H., Birkner E., Ślusarczyk K.: Concentration of TNF-α and Il-1-β in Wistar rats serum and lymph under physiological conditions. Eur. J. Lymphol. Rel. Probl. 2004, 14, 3-5.
• 6.Beck B., Ciszek M., Tarnawski R.: Limfa - skład biochemiczny, znaczenie jej krążenia w fizjologii i patologii organizmu. Post. Hig. Med. Dośw. 1995, 49, 353-366.
• 7.Campbell K. M., Sabla G. E., Bezerra J. A.: Transcriptional reprogramming in murine liver defines the physiologic consequences of biliary obstruction. J. Hepatol. 2004, 40, 14-23.
• 8.Desmouliere A., Xu G., Costa A. M. A., Yousef I. M., Gabbiani G., Tuchweber B.: Effect of pentoxifylline on early proliferation and phenotypic modulation of fibrogenic cells in two rat models of liver fibrosis and on cultured hepatic stellate cells. J. Hepatol. 1999, 30, 621-631.
• 9.Haveman J., James J., Geerdink A.: Collagen content in rat liver after experimentally induced cholestasis followed by choledochojejunostmy and X-irradiation. Liver 1996, 16, 195-200.
• 10.Huth F., Wilde A., Schulten H. J., Berger S., Davaris P., Baden E.: X-ray, ligh and elektron microscopie observations in experimental lymphostasis of the liver. Antiologica 1972, 9, 40-52.
• 11.Krawczyński J.: Diagnostyka enzymatyczna. PZWL, Warszawa 1972.
• 12.Lee E, Ross B. C., Haines J. R.: The effect of experimental bile duct obstruction on critical biosynthetic functions of the liver. Brit. J. Surg. 1972, 59, 564-569.
• 13.Lie T. S., Seifert G., Fasske E., Nakano H., Ebata H., Bartsch G.: Experimentelle Lymphostase der Leber. Leber Magen Darm. 1974, 6, 313-316.
• 14.Louis H., van Laethem J.-L., Wu W., Quertinmont E., Degraef C., van den Berg K., Demols A., Goldman M., Le Moine O., Geerts A., Deviere J.: Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice. Hepatology 1998, 28, 1607-1615.
• 15.Lowry O. A., Rosenbrough N. J., Farr A. L., Randall R. J.: Protein measurement with the Folin phenol reagen. J. Biol. Chem. 1951, 193, 265-275.
• 16.Mazur W., Gonciarz M., Gonciarz Z.: Włóknienie wątroby - aspekty kliniczne. Medycyna po Dyplomie 2003, 12, 30-39.
• 17.Muriel P., Deheza R.: Fibrosis and glycogen stores depletion induced by prolonged biliary obstruction in the rat ameliorated by metadoxine. Liver Internat. 2003, 23, 262.
• 18.Ozawa K., Yamada T., Tanaka J., Ukikusa M., Tobe T.: The mechanism of suppression of renal function in patients and rabbits with jaundice. Surg. Ginecol. Obstet. 1979, 149, 54-60.
• 19.Romij J. A., Endert E., Sauerwein P.: Glucose and fat metabolism during short-term starvation in cirrhosis. Gastroenterology 1991, 100, 731-737.
• 20.Schmidt E., Schmidt S. W.: Progress in the enzyme diagnosis of the liver disease: reality or illusion. Clin. Biochem. 1990, 23, 375-383.
• 21.Szabo G., Jakab F., Sugar I.: The effect of the occlusion of liver lymphatics on hepatic blood flow. Res. Exp. Med. (Berl). 1976, 169, 1-7.
• 22.Ślusarczyk K.: Anatomia dróg odpływu chłonki i regionalnych węzłów chłonnych wątroby szczurów szczepu Wistar i Lewis. Praca hab. Śląska Akademia Medyczna, Katowice 1990.
• 23.Witte M. H.: Horizons in hepatic lymphology, [w:] Bartos V., Davidson J. W. (red.): Advances in Lymphology. Avicenum, Czech Med. Press, Praha 1981, 556-559.