Forty-three C.f.s.f. strains and 19 C. jejuni strains from miscarried sheep foetuses and rectal mucosa smears were isolated. The C.f.s.f. strains were used to prepare 4 vaccines. The dynamics of the occurrence of antibodies against anti-Campylobacter in the sheep immunized with these vaccines was similar. The highest mean titres were found from experimental weeks 8 to 10. The vaccine applied in disease focus revealed satisfactory protective properties. The results obtained made it possible to select the strains which can be used for immunization of sheep.