PL
Analizowano humoralną odpowiedź immunologiczną, indukowaną przez mutant temperaturowrażliwy wirusa herpes simplex typu - 1 (mutant ts HSV-1) w obecności innych atenuowanych szczepów wirusowych. Zbadano również wpływ mutanta ts HSV-1 na odpowiedź immunologiczną, indukowaną przez inne szczepy wirusowe, wchodzące w skład poliwalentnych układów szczepienia (atenuowane szczepy wirusa odry i wirusa nagminnego zapalenia przyusznic).
EN
The ability of mutant is HSV-1 on 45 passage to induction of IgG antibody response in the presence of other attenuated viral strain, like measles, mumps, rubella was evaluated, and the effect of mutant to HSV-1 on humoral immunity induced by attenuated measles and mumps strains was also tested. The obtained results clearly indicated that even immunization with other RNA virus strains had no effect on IgG antibody response ta mutant ts HSV-J. Significant differences were observed in IgG antibody responses to mumps and measles between groups of guinea pigs immunized with these viruses alone or together with other viruses. This was especially observed in the case of mumps virus. It clearly shows that change of virus concentration rates in polyvalent schema of immunization is needed.