EN
Rubacha, G., Orlowska-Majdak, M. and Traczyk W. Z.: The effect of Substance P (SP) infusion above the supraoptic nuclei of hypothalamus on the vasopTessin content in the posterior pituitary lobe after haemorrhage in rats. Acta physiol, pol., 1933, 39 (3): 175-182. Dekanski’s method was used to estimate the pressor activity of the extracts of the posterior pituitary lobe in anaesthetized rats, after the infusion of 0.9% NaCl solution above the supraoptic nuclei and haemorrhage in the amount of l.5% of body weight or after the infusion of Substance P solution above the supraoptic nuclei and haemorrhage. It has been found that the vasopressin content in the posterior pituitary lobe decreased about 20% after the infusion of 0.9% NaCl solution and haemorrhage. The infusion of Substance P above the supraoptic nuclei inhibits the loss of vasopressin from the pituitary caused by haemorrhage.