Estimation of functional reserves of the body and risk of cardiovascular events in patients with myocardial infarction with comorbid pathology undergoing rehabilitation

• Autorzy: Levytska L. , Shved M. , Korda M.

Warianty tytułu

PL

Ocena rezerw funkcjonalnych organizmu oraz ryzyka zdarzeń sercowo-naczyniowych u pacjentów po przebytym zawale mięśnia sercowego z rozpoznaniem chorób współwystępujących będących w trakcie rehabilitacji

• Języki publikacji: EN

Abstrakty

EN

Background. Cardiovascular diseases are the leading cause of death worldwide. In Ukraine, cardiovascular mortality is 66.7%. Material and methods. We examined 371 patients with myocardial infarction ( MI) with comorbid pathology who had undergone 90 days of rehabilitation. We studied the possibility of quantitative estimation of comorbid pathology, the condition of functional reserves in patients with MI, their connection with clinical markers of reduced exercise tolerance and comorbidity index. Results. We established close correlations between the six-minute walk tests conducted on the 10th, 30th and 90th days of rehabilitation (6MWT10, 6MWT30 and 6MWT90) with age of patients (r6MWT10 = -0.199; r6MWT30 = -0.287; r6MWT90 = -0.410 P < 0.05), SpO₂ (r6MWT10 = -0.399; r6MWT30 = -0.265; r6MWT90 = -0.248; P < 0.05), left ventricular ejection fraction (r6MWT10 = 0.706; r6MWT30 = -0.670; r6MWT90 = -0.583; P < 0.0001), troponin levels (r6MWT10 = -0.210; r6MWT30 = -0.312; P < 0.05); creatinine (r6MWT10 = -0.148; P < 0,05) and Charlson comorbidity index (r6MWT10 = -0.323; r6MWT30 = -0.398; r6MWT90 = -0.427; P < 0.0001). Conclusions. Markers of reduced exercise tolerance in patients with MI were age, SpO₂, ejection fraction, levels of troponin, creatinine, lymphocytes, Charlson comorbidity index.

PL

Wprowadzenie. Choroby układu krążenia są główną przyczyną śmiertelności na całym świecie. Na Ukrainie wskaźnik śmiertelności związanej z chorobami układu krążenia wynosi 66,7%. Materiał i metody. Badaniem objęto 371 pacjentów po przebytym zawale mięśnia sercowego (MI) z rozpoznaniem chorób współistniejących, będących w trakcie 90-dniowej rehabilitacji. Przeanalizowano możliwość ilościowego oszacowania chorób współistniejących, stanu rezerw funkcjonalnych u pacjentów po przebytym zawale mięśnia sercowego oraz związku pomiędzy klinicznymi markerami obniżonej tolerancji wysiłku a wskaźnikami zachorowalności. Wyniki. Ścisła korelacja pomiędzy testem marszu sześciominutowego przeprowadzonym w 10, 30 i 90 dniu rehabilitacji (6MWT10, 6MWT30 i 6MWT90) a wiekiem pacjentów (r6MWT10 = -0,199; r6MWT30 = -0,287; r6MWT90 = -0,410 P < 0,05), SpO₂ (r6MWT10 = -0,399; r6MWT30 = -0,265; r6MWT90 = -0,248; P < 0,05), frakcją wyrzutową lewej komory (r6MWT10 = 0,706; r6MWT30 = -0,670; r6MWT90 = -0,583; P < 0.0001), poziomami troponiny (r6MWT10 = -0,210; r6MWT30 = -0,312; P < 0,05); kreatyniny (r6MWT10 = -0,148; P < 0,05) oraz wskaźnikiem chorób współistniejących Charlsona (r6MWT10 = -0,323; r6MWT30 = -0,398; r6MWT90 = -0,427; P <0,0001). Wnioski. Markerami obniżonej tolerancji wysiłku u pacjentów z MI był wiek, SpO₂, frakcja wyrzutowa, poziom troponiny, kreatyniny, limfocytów oraz wskaźnik chorób współistniejących Charlsona.

Słowa kluczowe

EN

functional reserve; human body; human disease; disease risk; cardiovascular event; patient; myocardial infarction; acute myocardial infarction; comorbidity; pathology; rehabilitation

• Wydawca: -
• Czasopismo: Health Problems of Civilization
• Rocznik: 2019
• Tom: 13
• Numer: 3
• Opis fizyczny: p.178-186,fig.,ref.

Twórcy

autor

Levytska L.

• Ivan Horbachevsky Ternopil State Medical University, Ternopil, Ukraine

autor

Shved M.

• Ivan Horbachevsky Ternopil State Medical University, Ternopil, Ukraine

autor

Korda M.

• Ivan Horbachevsky Ternopil State Medical University, Ternopil, Ukraine

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Identyfikatory

DOI

10.5114/hpc.2019.86209