The autistic mind in the light of neuropsychological studies

• Autorzy: Pisula E.
• Języki publikacji: EN

Abstrakty

EN

The underlying causes of autism spectrum disorders have not yet been identified. There is a group of theories which attempt to explain the source of difficulties experienced by people with these disorders through neurocognitive deficits. The most popular among them refer to deficits in theory of mind, executive dysfunction and weak central coherence. The results of over 20 years of research show that although these deficits may at least partially explain variations in the course of social development, communication difficulties and the formation of rigid patterns of behavior and interests in individuals with autism, none of them is sufficient on its own to comprehensively explain the complex picture of autistic disorders. Information about the neurobiological correlates of these deficits complement our knowledge about their mutual relationships by showing that multiple neural networks are involved in the emergence of autism’s signs and symptoms. Further investigation of various aspects of these cognitive deficits and the relationships between them may significantly improve our understanding of processes involved in the development of autism.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2010
• Tom: 70
• Numer: 2
• Opis fizyczny: p.119-130,ref.

Twórcy

autor

Pisula E.

• Faculty of Psychology, University of Warsaw, Warsaw, Poland

Bibliografia

• APA [American Psychiatric Association] (2000) Diagnostic and Statistical Manual of Mental Disorders (4th ed. Text Revision). American Psychiatric Association, Washington, D.C. Barnhill G, Hagiwara T, Smith Myles B, Simpson RL (2000) Asperger syndrome: A study of the cognitive profiles of 37 children and adolescents. Foc Aut Other Dev Disabil 15: 146-153.
• Baron-Cohen S, Leslie AM, Frith U (1985) Does the autistic child have a 'theory of mind'? Cognition 21: 37-46.
• Baron-Cohen S, O'Riordan M, Stone V, Jones R, Plaisted K (1999) Recognition of faux pas by normally developing children and children with Asperger syndrome or high- functioning autism. J Autism Dev Disord 29: 407-418.
• Baron-Cohen S, Ring HA, Bullmore ET, Wheelwright S, Ashwin C, Williams SC (2000) The amygdala theory of autism. Neurosci Biobehav Rev 24: 355-364.
• Bauminger N (2004) The expression and understanding of jealousy in children with autism. Dev Psychopathol 16: 157-177.
• Beaumont R, Newcombe P (2006) Theory of mind and cen­tral coherence in adults/ with high-functioning autism or Asperger syndrome. Autism 10: 365-382.
• Beaumont RB, Sofronoff K (2008) A new computerised advanced theory of mind measure for children with Asperger syndrome: The ATOMIC. J Autism Dev Disord 38: 249-260.
• Begeer S, Rieffe C, Terwogt MM, Stockmann L (2006) Attention to facial emotion expressions in children with autism. Autism 10: 37-51.
• Belmonte MK (2009) What's the story behind 'theory of mind' and autism? J Consciousness Stud 16: 118-139.
• Best CS, Moffat VJ, Power MJ, Owens DG, Johnstone EC (2008) The boundaries of the cognitive phenotype of autism: theory of mind, central coherence and ambiguous figure perception in young people with autistic traits. J Autism Dev Disord 38: 840-847.
• Bishop DVM, Norbury CF (2005) Executive functions in chil­dren with communication impairments, in relation to autistic symptomatology. 2: Response inhibition. Autism 9: 29-43.
• Bogte H, Flamma B, van der Meere J, van Engeland H (2008) Cognitive flexibility in adults with high function­ing autism. J Clinical Exp Neuropsychol 30: 33-41.
• Bolte S, Poustka F (2006) The broader cognitive phenotype of autism in parents: how specific is the tendency for local processing and executive dysfunction? J Child Psychol Psychiatry 47: 639-645.
• Brock J, Brown CC, Boucher J, Rippon G (2002) The tem­poral binding deficit hypothesis of autism. Dev Psychopathol 14: 209-224.
• Brunet E, Sarfate Y, Hardy-Bayle MC, Decety J (2000) A PET investigation of the attribution of intentions with a nonverbal task. Neuroimage 11: 157-166.
• Burnette CP, Mundy PC, Meyer JA, Sutton SK, Vaughan AE, Charak D (2005) Weak central coherence and its relations to theory of mind and anxiety in autism. J Autism Dev Disord 35: 63-73.
• Castelli F (2005) Understanding emotions from standard­ized facial expressions in autism and normal develop­ment. Autism 9: 428-449.
• Castelli F, Happé F, Frith U, Frith CD (2000) Movement and mind: a functional imaging study of perception and inter­pretation of complex intentional movement patterns. Neuroimage 12: 314-325.
• Castelli F, Frith C, Happé F, Frith U (2002) Autism, Asperger syndrome and brain mechanisms for the attribution of mental states to animated shapes. Brain 125: 1839-1849.
• Chen YH, Rodgers J, McConachie H (2009) Restricted and repetitive behaviours, sensory processing and cognitive style in children with autism spectrum disorders. J Autism Dev Disord 39: 635-642.
• Colle L, Baron-Cohen S, Hill J (2007) Do children with autism have a theory of mind? A non-verbal test of autism vs. specific language impairment. J Autism Dev Disord 37: 716-723.
• Colle L, Baron-Cohen S, Wheelwright S, van der Lely HKJ (2008) Narrative discourse in adults with high-function­ing autism or Asperger syndrome. J Autism Dev Disord 38: 28-40.
• Corbett BA, Constantine LJ, Hendren R, Rocke D, Ozonoff S (2009) Examining executive functioning in children with autism spectrum disorder, attention deficit hyperac- tivity disorder and typical development. Psychiatry Res 166: 210-222.
• Craig AD, Chen K, Bandy D, Reiman EM (2000) Thermosensory activation of insular cortex. Nat Neurosci 3: 184-190.
• Critchley HD, Daly EM, Bullmore ET, Williams SC, Van Amelsvoort T, Robertson DM, Rowe A, Phillips M, McAlonan G, Howlin P, Murphy DG (2000) The func­tional neuroanatomy of social behaviour: Changes in cerebral blood flow when people with autistic disorder process facial expressions. Brain 123: 2203-2212.
• De C. Hamilton AF (2009) Research review: Goals, inten­tions and mental states: challenges for theories of autism. J Child Psychol Psychiatry 50: 881-892.
• Dawson G, Toth K, Abbott R, Osterling J, Munson J, Estes A, Liaw J (2004) Early social attention impairments in autism: social orienting, joint attention, and attention to distress. Dev Psychol 40: 271-283.
• Delorme R, Goussé V, Roy I, Trandafir A, Mathieu F, Mouren-Siméoni MCh, Betancur C, Leboyer M (2007) Shared executive dysfunctions in unaffected relatives of patients with autism and obsessive-compulsive disorder. Eur Psychiatry 22: 32-38.
• Egeth M, Kurzban R (2008) Representing metarepresenta- tions: is there theory of mind-specific cognition? Conscious Cogn 18: 244-254.
• Fombonne E (2003) Epidemiological surveys of autism and other pervasive developmental disorders: an update. J Autism Dev Disord 33: 365-382.
• Frith U 2003 (first edition in 1989) Autism: Explaining the Enigma. Blackwell Publishing Ltd., Oxford, UK.
• Frith U, Happé F (1994) Autism: beyond 'theory of mind'. Cognition 50: 115-132.
• Frith CD, Frith U (2008) The self and its reputation in autism. Neuron 57: 331-332.
• Gallagher H, Happé F, Brunswick N, Fletcher PC, Frith U, Frith CD (2000) Reading the mind in cartoons and sto­ries: a fMRI study of 'theory of mind' in verbal and non­verbal tasks. Neuropsychol 38: 11-21.
• Geurts HM, Verté S, Oosterlaan J, Roeyers H, Sergeant JA (2004) How specific are executive functioning deficits in attention deficit hyperactivity disorder and autism? J Child Psychol Psychiatry 45: 836-854.
• Golan O, Baron-Cohen S, Hill JJ, Rutherford MD (2007) The 'Reading the Mind in the Voice' test-revised: a study of complex emotion recognition in adults with and with­out autism spectrum conditions. J Autism Dev Disord 37: 1096-1106.
• Goldstein G, Beers SR, Siegel DJ, Minshew NJ (2001) A comparison of WAIS-R profiles in adults with high- functioning autism or differing subtypes of learning dis­ability. Appl Neuropsychol 8: 148-154.
• Happé FG (1994) Wechsler IQ profile and theory of mind in autism: a research note. J Child Psychol Psychiatry 35: 1461-1471.
• Happé FG (1995) The role of age and verbal ability in the theory of mind task performance of subjects with autism. Child Dev 66: 843-855.
• Happé F, Ehlers S, Fletcher P, Frith U, Johansson M, Gillberg C, Dolan R, Frackowiak R, Frith C (1996) "Theory of mind" in the brain: evidence from a PET scan study of Asperger syndrome. Neuroreport 8: 197-201.
• Happé F, Briskman J, Frith U (2001) Exploring the cognitive phenotype of autism: Weak 'central coherence' in parents and siblings of children with autism: I. Experimental tests. J Child Psychol Psychiatry 42: 299-307.
• Happé F, Booth R, Charlton R, Hughes C (2006) Executive function deficits in autism spectrum disorders and atten- tion-deficit/hyperactivity disorder: Examining profiles across domains and ages. Brain Cogn 61: 25-39.
• Happé F, Frith U (2006) The weak coherence account: Detail-focused cognitive style in autism spectrum disor­ders. J Autism Dev Disord 36: 5-25.
• Happé F (2009) What aspects of autism predispose to talent? Phil Trans R Soc Lond B 364: 1369-1375.
• Hill C, Berthoz S, Frith U (2004) Cognitive processing of own emotions in individuals with autistic spectrum disorder and in their relatives. J Autism Dev Disord 34: 229-235.
• Hill EL, Frith U (2003) Understanding autism: insights from mind and brain. Phil Trans R Soc Lond B 358: 281-289.
• Homer M, Rutherford MD (2008) Individuals with autism can categorize facial expressions. Child Neuropsychol 14: 419-437.
• Jarrold Ch, Butler DW, Cottington EM, Jimenez F (2000) Linking theory of mind and central coherence bias in autism and in the general population. Dev Psychol 36: 126-138.
• Johnson KA, Robertson IH, Kelly SP, Silk TJ, Barry E, Daibhis A, Watchorn A, Keavey M, Fitzgerald M, Gallagher L, Gill M, Bellgrove MA (2007) Dissociation in performance of children with ADHD and high-func­tioning autism on a task of sustained attention. Neuropsychologia 45: 2234-2245.
• Jolliffe T, Baron-Cohen S (1999) A test of central coherence theory: linguistic processing in high-functioning adults with autism or Asperger syndrome: is local coherence impaired? Cognition 71: 149-185.
• Jolliffe T, Baron-Cohen S (2000) Linguistic processing in high-functioning adults with autism or Asperger's syn­drome. Is global coherence impaired? Psychol Med 30: 1169-1187.
• Jones W, Carr K, Klin A (2008) Absence of preferential looking to the eyes of approaching adults predicts level of social disability in 2-year-old toddlers with autism spec­trum disorder. Arch Gen Psychiatry 65: 946-954.
• Joseph RM, Tager-Flusberg H, Lord C (2002) Cognitive profiles and social-communicative functioning in childrenwith autism spectrum disorder. J Child Psychol Psychiatry 43: 807-821.
• Just MA, Cherkassky VL, Keller TA, Minshew NJ (2004) Cortical activation and synchronization during sequence comprehension in high functioning autism: Evidence of underconnectivity. Brain 127: 1811-1821.
• Kaland N, Mortensen EL, Smith L (2007) Disembedding performance in children and adolescents with Asperger syndrome or high-functioning autism. Autism 11: 81-92.
• Kaland N, Callesen K, Moller-Nielsen A, Lykke Mortensen E, Smith L (2008) Performance of children and adoles­cents with Asperger syndrome or high-functioning autism on advanced theory of mind tasks. J Autism Dev Disord 38: 1112-1123.
• Kana RK, Keller TA, Minshew NJ, Just MA (2007) Inhibitory control in high-functioning autism: decreased activation and underconnectivity in inhibition networks. Biol Psychiatry 62: 198-206.
• Keary CJ, Minshew NJ, Bansal R, Goradia D, Fedorov S, Keshavan MS, Hardan AY (2009) Corpus callosum vol­ume and neurocognition in autism. J Autism Dev Disord 39: 834-841.
• Klin A, Jones W, Schultz R, Volkmar F, Cohen D (2009) Two-year-olds with autism orient to non-social contin­gencies rather than biological motion. Arch Gen Psychiatry 59: 809-816.
• Kohls G, Peltzer J, Herpertz-Dahlmann B (2009) Differential effects of social and non-social reward on response inhibi­tion in children and adolescents. Dev Science 12: 614-625.
• Leslie AM, Friedman O, German TP (2004) Core mecha­nisms in 'theory of mind'. Trends Cogn Sci 8: 528-533.
• Levy F (2007) Theories of autism. Aust N Z J Psychiatry 41: 859-868.
• López B, Leekam SR, Arts GR (2008) How central is central coherence? Preliminary evidence on the link between conceptual and perceptual processing in children with autism. Autism 12: 159-171.
• Luna B, Doll SK, Hegedus SJ, Minshew NJ, Sweeney JA (2007) Maturation of executive function in autism. Biol Psychiatry 61: 474-481.
• Mevorach C, Humphreys GW, Shalev L (2005) Attending to local form while ignoring global aspects depends on hand­edness: evidence from TMS. Nat Neurosci 8: 276-277.
• Miller CA (2006) Developmental relationships between language and theory of mind. American J Speech-Lang Pathol 15: 142-154.
• Molesworth CJ, Bowler DM, Hampton JA (2005) The pro­totype effect in recognition memory: intact in autism? J Child Psychol Psychiatry 46: 661-672.
• Noens I, van Berckelaer-Onnes I (2004) Making sense in a fragmentary world: Communication in people with autism and learning disability. Autism 8: 197-218.
• O'Hearn K, Asato M, Ordaz S, Luna B (2008) Neurodevelopment and executive function in autism. Dev Psychopat 20: 1103-1132.
• Ozonoff S (1997) Causal mechanisms of autism: Unifying perspectives from an information-processing framework. In: Handbook of Autism and Pervasive Developmental Disorders Neurological Aspects of Autism (Cohen DJ, Volkmar FR, Eds). Wiley & Sons, New York, NY, p. 868-879.
• Ozonoff S, Strayer DL (1997) Inhibitory function in nonretarded children with autism. J Autism Dev Disord 27: 59-77.
• Peterson CC (2005) Mind and body: concepts of human cognition, physiology and false belief in children with autism or typical development. J Autism Dev Disord 35: 487-497.
• Peterson CC, Slaughter VP, Paynter J (2007) Social maturity and theory of mind in typically developing children and those on the autism spectrum. J Child Psychol Psychiatry 48: 1243-1250.
• Pietrefesa AS, Evans DW (2007) Affective and neuropsychological correlates of children's rituals and compulsive­like behaviors: Continuities and discontinuities with obsessive-compulsive disorder. Brain Cogn 65: 36-46.
• Pierce K, Muller RA, Ambrose J, Allen G, Courchesne E (2001) Face processing occurs outside the fusiform 'face area' in autism: evidence from functional MRI. Brain 124: 2059-2073.
• Premack D, Woodruff G (1978) Does the chimpanzee have a theory of mind? Behav Brain Sci 1: 515-526.
• Raymaekers R, van der Meere J, Roeyers H (2004) Event­rate manipulation and its effect on arousal modulation and response inhibition in adults with high functioning autism. J Clin Exp Neuropsychol 26: 74-82.
• Raymaekers R, Antrop I, van der Meere JJ, Wiersema JR, Roeyers H (2007) HFA and ADHD: A direct comparison on state regulation and response inhibition. J Clin Exp Neuropsychol 29: 418-427.
• Rinehart NJ, Bradshaw JL, Moss SA, Brereton AV, Tonge BJ (2000) Atypical interference of local detail on global pro­cessing in high-functioning autism and Asperger's disor­der. J Child Psychol Psychiatry 41: 769-778.
• Robinson S, Goddard L, Dritschel B (2009) Executive func­tions in children with autism spectrum disorders. Brain Cogn 71: 362-368.
• Ronald A, Viding E, Happé F, Plomin R (2006) Individual differences in theory of mind ability in middle childhood and links with verbal ability and autistic traits: A twin study. Soc Neurosci 1: 412-425.
• Ropar D, Mitchell P (2001) Susceptibility to illusions and performance on visuospatial tasks in individuals with autism. J Child Psychol Psychiatry 42: 539-549.
• Ruffman T, Garnham W, Rideout P (2001) Social under­standing in autism: Eye gaze as a measure of core insights. J Child Psychol Psychiatry 42: 1083-1094.
• Rutherford MD, Baron-Cohen S, Wheelwright S (2002) Reading the mind in the voice: a study with normal adults and adults with Asperger syndrome and high functioning autism. J Autism Dev Disord 32: 189-194.
• Rutherford MD, Towns AM (2008) Scan path differences and similarities during emotion perception in those with and without autism spectrum disorders. J Autism Dev Disord 38: 1371-1381.
• Sabbagh MA, Taylor M (2000) Neural correlates of theory- of-mind reasoning: an event-related potential study. Psychol Sci: 11: 46-50.
• Sabbagh MA (2004) Understanding orbitofrontal contribu­tions to theory-of-mind reasoning: Implications for autism. Brain Cognit 55: 209-219.
• Sanders J, Johnson KA, Garavan H, Gill H, Gallagher L (2008) A review of neuropsychological and neuroimaging research in autistic spectrum disorders: Attention, inhibi­tion and cognitive flexibility. Res Aut Spect Disord 2: 1-16.
• Scholz J, Triantafyllou Ch, Whitfield-Gabrieli S, Brown EN, Saxe R (2009) Distinct regions of right temporo-parietal junction are selective for theory of mind and exogenous attention. PloS ONE 4: e4869.
• Schultz RT, Gauthier I, Klin A, Fulbright RK, Anderson AW, Volkmar F, Skudlarski P, Lacadic C, Cohen DJ, Gore JC (2000) Abnormal ventral temporal cortical activity during face discrimination among individuals with autism and Asperger syndrome. Arch. Gen. Psychiatry 57: 331-340.
• Silani G, Bird G, Brindley R, Singer T, Frith C, Frith U (2008) Levels of emotional awareness and autism: an fMRI study. Soc Neurosci 3: 97-112.
• South M, Ozonoff S, McMahon WM (2007) The relation­ship between executive functioning, central coherence, and repetitive behaviors in the high-functioning autism spectrum. Autism 11: 437-451.
• Speer LL, Cook AE, McMahon WM, Clark E (2007) Face processing in children with autism: effects of stimulus contents and type. Autism 11: 265-277.
• Spence SA, Hunter MD, Farrow TF, Green RD, Leung DH, Hughes CJ, Ganesan V (2004) A cognitive neurobiological account of deception: evidence from functional neu- roimaging. Phil Trans R Soc Lond B 359: 1755-1762.
• Stone VE, Gerrans P (2006) What's domain-specific about theory of mind? Soc Neurosci 1: 309-319.
• Tager-Flusberg H, Paul R, Lord C (2005) Language and communication in autism. In: Handbook of Autism and Pervasive Developmental Disorders (Volkmar FR, Paul R, Klin A, Cohen D, Eds). John Wiley & Sons, Inc. Hoboken, NJ, p. 335-364.
• Tager-Flusberg H (2007) Evaluating the theory-of-mind hypothesis of autism. Curr Directions Psychol Science 16: 311-315.
• Teunisse JP, Cools AR, van Spaendonck KP, Aerts FH, Berger HJ (2001) Cognitive styles in high-functioning adolescents with autistic disorder. J Autism Dev Disord 31: 55-66.
• van Lang ND, Bouma A, Sytema S, Kraijer DW, Minderaa RB (2006) A comparison of central coherence skills between adolescents with an intellectual disability with and without comorbid autism spectrum disorder. Res Dev Disabil 27: 217-226.
• Vogeley K, Bussfeld P, Newen A, Herrmann S, Happé F, Falkai P, Maier W, Shah NJ, Fink GR, Zilles K (2001) Mind reading: neural mechanisms of theory of mind and self-perspective. Neuroimage 14: 170-181.
• Volkmar FR, Lord C, Bailey A, Schultz R, Klin A (2004) Autism and pervasive developmental disorders. J Child Psychol Psychiatry 45: 135-170.
• Waiter GD, Williams JH, Murray AD, Gilchrist A, Perrett DI, Whiten A (2005) Structural white matter deficits in high- functioning individuals with autistic spectrum disorder: A voxel-based investigation. Neuroimage 24: 455-461.
• Walenski M, Tager-Flusberg H, Ullman MT (2006) Language in autism. In: Understanding Autism. From Basic Neuroscience to Treatment (Moldin SO, Rubenstein JLR, Eds). Taylor & Francic Group, Boca Raton, FL, p. 175-203.
• White S, O'Reilly H, Frith U (2009) Big heads, small details and autism. Neuropsychologia 47: 1274-1281.
• WHO [World Health Organization] (1992) Manual of the International Statistical Classification of the Diseases, and Related Health Problems. World Health Organization, Geneva, CH.
• Wimmer H, Perner J (1983) Beliefs about beliefs: Representation and constraining function of wrong beliefs in young children's understanding of deception. Cognition 13: 103-128.
• Yang J, Zhou S, Yao S, Su L, McWhinnie Ch (2009) The relationship between theory of mind and executive func­tion in a sample of children from mainland china. Child Psychiatry Hum Dev 40: 169-182.

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