EN
The interactions between the hormonal, neurohormonal and immune systems as the one complex system that maintains body homeostasis have been described. The immune system is capable of producing monokines, lymphokines, thymosins and POMC-related peptides in response to immune stimulators which directly or indirectly stimulate or inhibit neuroendocrine hormonal regulatory centers. This action is reciprocal and the immune system is subject to endocrine and neuroendocrine control. On the basis of the presented experimental findings an existence of a regulatory circut between the hormone and immune system, which in the case of the hypothalamo-pituitary-adrenal axis and the hypothalamo-pituitary-gonadal axis is manifested by the feedback control, has been postulated.