EN
The aim of the study was to determine the activities of glutathione peroxidase (GSH-Px), superoxide dismutase, and catalase in the uterine tissues of bitches with pyometra. The uterus from 11 bitches with pyometra and from 18 healthy bitches, which had undergone sterilisation (controls), were used. The activities of enzymes were determined in uterine tissue homogenisates using spectrophotometric methods. Lower GSH-Px activities in the uterine tissues of bitches with pyometra indicate deteriorated capacities of cells to protect against ROS and suggest possible involvement of oxidative stress in the aetiology and pathogenesis of pyometra. Further studies, however, are required to thoroughly elucidate this issue.