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1988 | 39 | 5-6 |

Tytuł artykułu

Secretion and metabolism of prostaglandin F2alfa by endometrial tissue obtained at different days of the oestrous cycle in cattle

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Kotwica, J., Schams, D. and Meyer,H.H.D.: Secretion and metabolism of prostaglandin F₂α by endometrial tissue obtained at different days of the oestrous cycle in cattle. Acta physiol, pol., 1908, 39(5-6): 404-490. Two mature heifers were slaughtered on days 3, 6-7, 10-11, 16, 18-19 or on day 21 of the oesterus cycle. Endometrium was incubated in quadruplicates with medium-199 at 37 C and a water saturated gas phase of 95% O₂ + 5% CO₂. Half ml medium samples were taken after 6, 12 and 24 h of incubation for determination of PGF₂α and PGFM. PGF₂α was secreted by endometrium at each stage of the oestrous cycle. Maximal secretion was measured around oestrus (p<0.01) compared with days 6-16 of the cycle. Concentration of PGFM in medium had a similar trend. Highest ability of endometrium for PGF₂α metabolism (indicated by the ratio PGF₂α:PGFM) was on days 6-16 of the cycle. Data suggest that PGF₂α metabolism by the endometrium may depend on ovarian steroids and that this metabolism may also protect the corpus luteum from the luteolytic action of PGF₂α besides reduced production of this prostaglandin during the luteal phase.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

39

Numer

5-6

Opis fizyczny

p.484-490,fig.,ref.

Twórcy

autor
  • Institute of Animal Physiology, University of Agriculture and Technology, Olsztyn-Kortowo, Poland
autor
  • Institut fur Physiology, Sudd. Versuchs- und Forschungsanstalt fur Milchwirtschaft, Technische Universitat Munchen, Freising-Weihenstephan, Germany
autor
  • Institut fur Physiology, Sudd. Versuchs- und Forschungsanstalt fur Milchwirtschaft, Technische Universitat Munchen, Freising-Weihenstephan, Germany

Bibliografia

  • 1. Casey, M.L., Hemsel, D.L., MacDonald, P.C. (1980) NAD-dependent 15-hydroxypro-staglandin dehydrogenase activity in human endometrium. Prostaglandins 19. 115-122.
  • 2. Enzenhofer, G. (1983) The studies on prostaglandin F₂α and E₂ and their 13,14-dihy- dro-15-keto-metalbolites in oestrous cycle in cattie. DVM Thesis, Technical University, Munich.
  • 3. Eairclough, R.J., Smith, J.F., McGowan, L.T. (1981) Prolongation of the oestrous cycle in cows and ewes after passive immunization with PGF antibodies. J. Reprod. Fert. 62. 213-219.
  • 4. Ferreira, S.A., Vane, J.R. (1967) Prostaglandins: their disappearance from the release into the circulation. Nature 216. 868-873.
  • 5. Guilbault, L.A., Thatcher, W.W., Foster, D.B., Caton, D. (1984) (Relationship of 15-keto-13,14-dihydro-prostagiandin F₂α concentrations inperipheral plasma with local uterine production of F series prostaglandins and changes in uterine blood flow during the early posit-partum period of cattle. Biol. Reprod. 31. 870-878.
  • 6. Hoffman, B., Kyrein, H.J., Ender, M.L. (1973) An efficient procedure for determination of progesterone by radioimmunoassay applied to bovine peripheral plasma. Hormone Res. 4. 302-310.
  • 7. Horton, E.W., Poyser, N.L. (1976) A physiological role for prostaglandin F₂α . Physiol. Rev. 56. 595-651.
  • 8. Ishikawa, M., Fuchs, A.R. (1978) Effects of epinephrine and oxytocin on the release of prostaglandin F from the rat uterus in vitro. Prostaglandins 15. 89-101.
  • 9. Kindahl, H., Edqvdst, L.E., Granstrom, E., Bane, A. (1976) The release of prostaglandin F₂α as reflected by 15-keto-13,14-dihydro-prostaglandin F₂α in the peripheral circulation durnig normal luteolysis in heifers. Prostaglandins 11. 871-8(8.
  • 10. Knickerbrooker, J.J., Thatcher, W.W., Foster, D.B., Wolfenson D., Bartol, F.F., Caton, D. (1986) Uterine prostaglandin and blood flow response to estradiol-17ß in cyclic cattle. Prostaglandins 31. 757-776.
  • 11. Lamothe, P., Bosquet, D., Guay, P. (1977) Cyclic variation of F prostaglandins in the uterine fluids of the cows. J. Reprod. Fert. 50. 381-382.
  • 12. Levis, G.S., Wilson, L., Wilks, J.W., Pexton, J.E., Fogwell, R.L., Ford, S.P., Butcher R.L., Thyne, W.V., Inskeep, E.K. (1977) PGF₂α and its metabolites in uterine and peripheral venous plasma and endometrium of ewes during early pregnancy. J. Anim. Sci. 45. 320-327.
  • 13. Louis, T.M., Parry, D.M., Robinson, J.S., Thorburn, G.D., Challis, J.R.G. (1977) Effects of exogenous progesterone and oestradiol on prostaglandin F₂α concentrations in uteri and plasma of ovariectoniized ewes. J. Endocrinol. 73. 427-439.
  • 14. Maule Walker, F.M., Peaker, M. (1931) Prostaglandins and lactation. Acta Vet. Scand., Suppl. 77. 299-310.
  • 15. Nancarrow, C.D., Buckmaster, J., Chamiey, W., Cox, R.J., Cumming, I.A., Findlay, J.K., Goding, J.R., Restall, B.J., Schneider, W., Thortburn, G.D. (1973) Hormone changes around oestrous in the cows. J. Reprod. Fert. 32. 320-301.
  • 16. Paterson, A.J., Fairclough, R.J., Payne, E., Smith, J.F. (1975) Hormone changes around bovine luteolysis. Prostaglandins. 10. 675-684.
  • 17. Rowson, L.E.A., Tervit, R., Brand, A. (1972) The use of prostaglandins for synchronization of oestrous in cattle. J. Reprod. Fert. 29. 145.
  • 18. Schallenberger, E., Meyer, H.H.D., Schams, D., Karg, H. (1985) Alternative hormonelle Mechanismen zur Erhaltung der Fruhgraviditat beim Rind. In Fortschritte der Fertilitatsiorschung FdF 13. Ed. C .Schirren pp. 16-23, Grosse Verlag, Berlin.
  • 19. Schams, D., Karg, H. (1969) Radioimmunologische LH-Bestimmung im Blutserum vom Rind unter besonderer Berucksichtigung des Brunstzyklus. Acta Endocrinol. 61. 96-103.
  • 20. Thatcher, W.W., Wilcox, C.J., Bazer, F.W., Collier, R.J., Eley, R.M., Stover, D.G., Bartol F.F. (1979) Bovine conceptus effects preparatum and potential carry over effects postpartum. In: Animal Reproduction. Ed H.W. Hawk, Symposium in Agriculture Research, pp. 259-271, Beltsville, Allanheld, Osmun and Co., Montclair N.J.
  • 21. Thatcher, W.W., Wolfenson, D., Curl, J.S., Rico, L.R., Knickerbrooker, J.J., Bazer, F.W., Drost, M. (1984) Prostaglandin dynamics associated with development of the bovine conceptus. Anim. Reprod. Sci. 7. 149-176.
  • 22. Watson, J., Patek, C.E. (1979) Steroid add prostaglandin secretion by the corpus luteum, endometrium and embryos of cyclic and pregnant pigs. J. Endocrinol. 82. 425-428.
  • 23. Wiltbank, J.N., Ingalls, J.E., Rowden, W.W. (1961) Effects of various forms and levels of estrogen alone or in combination with gonadotrophins on the estrous cycle of beef heifers, J. Anim. Sci. 20. 341-346.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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