Antimalarial drugs resistance genes of Plasmodium falciparum: A review

• Autorzy: Tchekounou C. , Zida A. , Zongo C. , Soulama I. , Sawadogo P.M. , Guiguemde K.T. , Sangare I. , Guiguemde R.T. , Traore Y.
• Języki publikacji: EN

Abstrakty

EN

Malaria remains the most common parasitic disease on the planet, with 229 million cases and 409,000 deaths worldwide in 2019, including 274,030 children under the age of 5. It is one of the most important infectious diseases in the world and its control is compromised by the spread of the parasite’s resistance to antimalarial drugs. This study aims to review the literature of resistant Plasmodium falciparum genes over the past twenty years. One hundred and five (105) articles were collected and read while the resistance of P. falciparum was being studied. Several P. falciparum gene resistances antimalarial drugs were discovered over the past twenty years. The most recent one is the Kelch13 gene of P. falciparum (Pfkelch13) which has showed resistance to artemisinin in Asia. In Africa, this gene represents a potential candidate for resistance to artemisinin, although no resistance was reported.

• Wydawca: -
• Czasopismo: Annals of Parasitology
• Rocznik: 2022
• Tom: 68
• Numer: 2
• Opis fizyczny: p.215-225,fig.,ref.

Twórcy

autor

Tchekounou C.

• Laboratoire de Biochimie et Immunologie Appliquees (LABIA), Departement de Biochimie-Microbiologie, Universite Joseph Ki-Zerbo (UJKZ), Burkina Faso
• Ecole de Sante Sciences Nouvelles (ESSN), Ouagadougou, Burkina Faso
• Institut International des Sciences et Technologie (IISTech), Ouagadougou, Burkina Faso

autor

Zida A.

• Laboratoire de Parasitologie-Mycologie du Centre Hospitalier Universitaire Yalgado Ouedraogo (CHUYO), Ouagadougou, Burkina Faso
• Ecole de Sante Sciences Nouvelles (ESSN), Ouagadougou, Burkina Faso
• Institut International des Sciences et Technologie (IISTech), Ouagadougou, Burkina Faso

autor

Zongo C.

• Laboratoire de Biochimie et Immunologie Appliquees (LABIA), Departement de Biochimie-Microbiologie, Universite Joseph Ki-Zerbo (UJKZ), Burkina Faso
• Ecole de Sante Sciences Nouvelles (ESSN), Ouagadougou, Burkina Faso
• Institut International des Sciences et Technologie (IISTech), Ouagadougou, Burkina Faso

autor

Soulama I.

• Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

autor

Sawadogo P.M.

• Laboratoire de Parasitologie-Mycologie du Centre Hospitalier Universitaire Yalgado Ouedraogo (CHUYO), Ouagadougou, Burkina Faso
• Ecole de Sante Sciences Nouvelles (ESSN), Ouagadougou, Burkina Faso
• Institut International des Sciences et Technologie (IISTech), Ouagadougou, Burkina Faso

autor

Guiguemde K.T.

• Centre Hospitalier Universitaire Charles De Gaulles, Ouagadougou, Burkina Faso

autor

Sangare I.

• Institut Superieur des Sciences de la Sante, Universite Nazi Boni, Burkina Faso

autor

Guiguemde R.T.

• Academie Nationale des Sciences, des Arts et des lettres, Ouagadougou, Burkina Faso

autor

Traore Y.

• Laboratoire de Biochimie et Immunologie Appliquees (LABIA), Departement de Biochimie-Microbiologie, Universite Joseph Ki-Zerbo (UJKZ), Burkina Faso

Identyfikatory

DOI

10.17420/ap6802.427