Anti-inflammatory effects of medicinal plants mixture used by Bedouin people in Saudi Arabia

• Autorzy: Elsharkawy E. , Elshathely M. , Jaleel G. A. , Al-Johar H. I.

Warianty tytułu

PL

Działanie antyoksydacyjne mieszanki roślin leczniczych używanej przez Beduinów w Arabii Saudyjskiej

• Języki publikacji: EN

Abstrakty

EN

Due to toxic and adverse side effects of synthetic drugs, traditional herbal medicine has the potential as a source of new bioactive molecules. That is why we investigated this research, searching new anti-inflammatory drugs from plants growing around us. The anti-inflammatory effect of the mixture of different plants used in traditional medicine (Alkanna tinctoria, Rubia tinctorum and Artemisia herba alba) were studied using carrageenan-induced paw edema (oil mixture extract 100 mg/kg and 200 mg/kg). These material reduces carrageenan-induced inflammation in rats and shows inhibition after 4 h especially at a concentration 200 mg/

PL

Ze względu na toksyczne i niepożądane działania leków syntetycznych, zioła stosowane w tradycyjnej medycynie są potencjalnym źródłem nowych związków biologicznie czynnych. Celem prowadzonych badań jest poszukiwanie nowych leków przeciwzapalnych na bazie roślin rosnących wokół nas. Działanie przeciwzapalne mieszanki ziół używanych w medycynie tradycyjnej (Alkanna tinctoria, Rubia tinctorum and Artemisia herba alba) sprawdzano w teście karageninowym obrzęku łapy szczura po podaniu wyciągu olejowego w dawce 100 mg/kg i 200 mg/kg masy ciała. Badany materiał redukował stan zapalny u szczurów wywołany karageniną po 4 godzinach zwłaszcza w stężeniu 200 mg/kg. Wyciąg olejowy badano za pomocą kapilarnej chromatografii genowej w porównaniu ze współczynnikiem retencji. Stwierdzono obecność około 17 składników: artemisol, epiglobulol i α-bisabolol są głównymi składnikami, a także olejek eteryczny i inne triterpeny: taraksasterol, stigmasterol, ursan-12-en, olean-12-en, betulin, germinkol, octan lupeolu i lupeol. Zidentyfikowano także inne związki heterocykliczne: morofolinę i piperidinol.

Słowa kluczowe

EN

antiinflammatory effect; medicinal plant; plant mixture; Bedouin; Saudi Arabia; traditional medicine; Alkanna tinctoria; Rubia tinctorum; Artemisia herba-alba; plant drug

• Wydawca: -
• Czasopismo: Herba Polonica
• Rocznik: 2013
• Tom: 59
• Numer: 3
• Opis fizyczny: p.76-87,fig.,ref.

Twórcy

autor

Elsharkawy E.

• Northern Border University - ARAR, North Region, Saudi Arabia
• Department of Eco Physiology, Desert Research Center, Mathef El-Mataria, 15753 Egypt

autor

Elshathely M.

• Northern Border University - ARAR, North Region, Saudi Arabia
• Department of Biology, Science Faculty for Girls, King Abdullaziz University, Jeddah, Saudi Arabia

autor

Jaleel G. A.

• Pharmacology Department, National Research Center, El-Bohoth St., Dokki, Saudi Arabia

autor

Al-Johar H. I.

• Saudi Food and Drug Authority, National Drug Control Laboratory, Riyadh, Saudi Arabia

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