Activity of selected aromatic amino acids in biological systems

• Autorzy: Krzysciak W.
• Języki publikacji: EN

Abstrakty

EN

 Besides the structural function in proteins, aromatic amino acids are precursors of many important biological compounds essential for normal functioning of the human organism. Many of these compounds may be used as markers for identification of specific pathological states. Comprehensive knowledge about the metabolism of aromatic amino acids and mechanisms of action of their metabolites made it possible to develop effective treatments for many disorders. However, it should not be forgotten that in some pathological conditions, these compounds could not only be involved in the pathogenesis of many disease entities but could also be used as an important tool in prediction of many diseases. This paper contains a review of published literature on aromatic amino acids in the context of physiological processes of the human body and chosen social disorders, such as cancers; psychiatric disorders: depression, anxiety states, schizophrenia, bipolar affective disorders; neurodegenerative, and cardiovascular diseases; chronic kidney insufficiency or diabetes.

Słowa kluczowe

EN

aromatic amino acid; biological system; tyrosine; kynurenic acid; reactive oxygen species; pathological condition; physiological process; human body; human disease; chronic venous disease; cytochrome P450; renal disease; lipopolysaccharide; tumour necrosis factor-alpha; diabetes; cardiovascular disease; neurodegenerative disease

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2011
• Tom: 58
• Numer: 4
• Opis fizyczny: p.461-466,fig.,ref.

Twórcy

autor

Krzysciak W.

• Department of Medical Diagnostics, Jagiellonian University, Medical College, Pharmacy Faculty, Krakow, Poland

Bibliografia

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