PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2015 | 66 | 3 |

Tytuł artykułu

Survey of polycyclic aromatic hydrocarbons and lead in Chinese teas sold in Nigeria: levels and health implications

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Background. The belief that Chinese teas are of immense health benefits by many Nigerians has led to high consumption rate. Objectives. This study has determined lead and polycyclic aromatic hydrocarbons (PAHs) levels of Chinese teas popularly consumed in Nigeria and to estimate the potential health risks. Material and Methods. Twenty brands of Chinese teas commonly consumed in Nigeria purchased in October 2014 were used in the study. Tea samples were extracted and digested. Lead, and PAHs were analyzed using an atomic absorption spectrophotometric (AAS) and gas chromatographic methods, respectively. Daily intake, percent violations of permissible limits, target hazard quotients (THQ), Health Risk Index (HRI) of lead, and other cancer risk parameters of PAHs were estimated. Results. All the tea samples except super natural green tea violated the WHO permissible limit of lead (0.01 mg/kg) by over 100%. The HRI ranged from 5.09 x 10-5 – 7.20 x 10-4 . Among the single analyzed compounds, the pyrenes had the highest concentration of 14.31 mg/kg. The intake of benzo[a]pyrene was detected in 25% of the samples which ranged from 0.066 to 0.145 mg/kg and exceeded the permissible daily limit of benzo[a]pyrene intake. The estimated cancer risk from this study in an adult is 5.07 x 10-9. Conclusion. The present study suggests that consumption of Chinese teas in Nigeria may not be one of the factors responsible for the increased rate of cancer in Nigeria.
PL

Wydawca

-

Rocznik

Tom

66

Numer

3

Opis fizyczny

p.225-232,ref.

Twórcy

  • Toxicology Unit, Clinical Pharmacy, Faculty of Pharmacy, University of Port-Harcourt, Rivers State, Nigeria
  • Department of Pharmacology, Faculty of Pharmacy, University of Uyo, Akwa Ibom State, Nigeria
autor
  • Department of Pharmacology, Faculty of Pharmacy, University of Uyo, Akwa Ibom State, Nigeria
  • Toxicology Unit, Clinical Pharmacy, Faculty of Pharmacy, University of Port-Harcourt, Rivers State, Nigeria

Bibliografia

  • 1. After stumbling, Mattel cracks down in China. New York Times August 22, 2008. Available at: http://www. nytimes.com/2007/08/29/business/worldbusiness/29mattel.html?_r=1&hp &oref=slogin. Accessed January 18,2008.
  • 2. Agency for Toxic Substance and Disease Registry. Public Health Assessment Guidance Manual (Update). U.S. Department of Health and Human Services, Atlanta, GA. January 2005.
  • 3. Agency for Toxic Substances and Disease Registry (ATSDR). Health Consultation, EPA FACILITY ID: OHN000510571 U.S. Department of Health and Human Services, Fostoria, Wood County, Ohio. February 2014.
  • 4. Arnich N, Sirot V, Riviere G, Jean J, Noel L, Guerin T, Leblanc J.C. : Dietary exposure to trace elements and health risk assessment in the 2nd French Total Diet Study. Food Chem Toxicol 2012; 50 (7): 2432-2449.
  • 5. Choi H, Jędrychowski W, Spengler J, Camann DE, Whyatt RM, Rauh V, Tsai WY, Perera, FP. : International studies of prenatal exposure to polycyclic aromatic hydrocarbons and fetal growth. Environ Health Perspect 2006; 114:1744–1750.
  • 6. Ciemniak A, Mocek K.: Polycyclic aromatic hydrocarbons in tea and the infusions. Rocz Panstw Zakl Hig 2010; 61(3):243-248.
  • 7. Cuadrado C, Kumpulainen J, Carvajal A, Moreiras O.: Cereals contribution to the total dietary intake of heavy metals in Madrid, Spain. J. Food Compos. 2000; 13: 495- 503.
  • 8. Ding X., Kamnsky LS.: Human extralepatic cytoctromes P450, function in Xenobiatic in metabolism and tissue selective chemical toxicity in the respiratory and gastrointestinal tracts. Annu Rev PharmacalToxicol 2003; 43:149-73.
  • 9. Falcon M, Viñas P, Luna A.:Placental lead and outcome of pregnancy. Toxicology 2003. 185: 59-66.
  • 10. Fasinu P, Orisakwe O.E.: Heavy metal pollution in sub-Saharan Africa and possible implication in cancer epidemic. Asian Pacific Journal of Cancer Prevention 2013; 14 (6):6111-6120.
  • 11. FDA’s Ongoing Pet Food Investigation. U.S. Food and Drug Administration. April 16, 2007. Available at: http://www.fda.gov/consumer/updates/petfoodrecallup.html.Accessed January 18, 2008.
  • 12. Fugh-Berman A.: Herb-drug interactions. The Lancet. 2000; 355.9198: 134-138.
  • 13. Jedrychowski WA, Perera FP, Majewska R. Mrozek-Budzyn D, Mroz E, Roen EL, Jacek R.: Depressed height gain of children associated with intrauterine exposure to polycyclic aromatic hydrocarbons (PAH) and heavy metals: the cohort prospective study. Environ Res 2015 Jan; 136:141-7; doi:10.1016/j.envres 2014.08.047.
  • 14. Jin Y, Liu P, Wu Y,Min J, Wang C, Sun J and Zhang Y.: A systematic review on food lead concentration and dietary lead exposure in China. Chin Med J 2014; 127 (15): 2844-2849.
  • 15. Koller K, Brown T, Spurgeon A, Levy L.: Recent development in low level lead exposure and intellectual impairment in children. Environ. Health Perspect 2004;112:987-994.
  • 16. Larsen JC, and Larsen PB. Chemical Carcinogens. In: Air Pollution and Health (Hester, R.E., and Harrison, R.M., Eds.), Issues in Environmental Sciences and Technology, 10, The Royal Society of Chemical, Cambridge 1998.
  • 17. Lichts F.O.: World Tea Markets Monthly. 2001, Draft for comments 26/06/02. Access date 7 April 2012.
  • 18. Mohammed AZ, Edino ST, Ochicha O, Gwarzo AK, Samaila AA.: Cancer in Nigeria: A 10 year analysis of the Kano cancer registry. Niger J Med 2008;17:280-4.
  • 19. Naufal Z, Zhiwen L, Zhu L, Zhou GD, McDonald T, He LY, Mitchell L, Ren A, Zhu H, Finnell R, Donnelly KC.: Biomarkers of exposure to combustion by-products in a human population in Shanxi, China. J. Expo. Sci. Environ 2010; 20:310–319.
  • 20. Orisakwe O.E.: Lead and cadmium in public health in Nigeria: physicians neglect and pitfall in patient management. North Am J Med Sci 2014;6:61-70.
  • 21. Orisakwe O.E.: The role of lead and cadmium in psychiatry. North American Journal of Medical Sciences 2014.
  • 22. Orisakwe OE, Jason L, Blum JL, Sabina S, Zelikoff JT.: Metal pollution in Nigeria: a biomonitoring update. Journal of Health & Population 2014;4(6):40-52.
  • 23. Parkhurst DF.: Arithmetic versus geometric means for environmental concentration data. Environ SciTechnol 1998; 32:92A-98A.
  • 24. Perera F, Li TY, Zhou ZJ, Yuan T, Chen YH, Qu L, Rauh VA, Zhang Y, Tang D. Benefits of reducing prenatal exposure to coal-burning pollutants to children’s neurodevelopment in China. Environ Health Perspect 2008; 116:1396–1400.
  • 25. Seenivasan S, Muraleedharan N.: Survey on the pesticide residues in tea in south India. Environ Monit Assess 2011; 176(1–4):365–371.
  • 26. Singh A, Sharma RK, Agrawal M, Marshall FM.: Risk assessment of heavy metal toxicity through contaminated vegetables from waste water irrigated area of Varanasi, India. Trop Ecol 2010; 51(2S): 375-387.
  • 27. Sweetman AJ, Alcock RE, Wittsiepe J, Jones KC.: Human exposure to PCDD/Fs in the UK: the development of a modelling approach to give historical and future perspectives. Environ. Int 2000; 26:37-47.
  • 28. Sylla BS, Wild CP.: A million Africans a year dying from cancer by 2030: What can cancer research and control offer to the continent? Int J Cancer, 30 August 2011, DOI: 10.1002/ijc.26333.
  • 29. U.S. Environmental Protection Agency. 2002. Polycyclic organic matter. U.S. Environmental Protection Agency. Available at: htpp://www.epa.gov/ttn/atw/hlthef/polycycl.html.
  • 30. U.S. seizes tainted toothpaste made in China. Reuters June 1, 2007. Available at: http://www.reuters.com/article/topNews/idUSWAT00764420070601?feedType=RSS. Accessed January 24, 2008.
  • 31. USEPA method 8100 National Technical Information Service, PB84-211614, Springfield, 1984 Virginia 22161, USA.
  • 32. Valavanidis A, Fiotakis K, Bakeas E, Vlahogianni T.: Electron paramagnetic resonance study of the generation of reactive oxygen species catalysed by transition metals and quinoid redox cycling by inhalable ambient particulate matter. Redox Rep 2005; 10:37–51.
  • 33. Valko M, Morris H. Cronin MTD. Metals, toxicity and oxidative stress. Curr Med Chem 2005;12:1161–208.
  • 34. Van Leeuwen F, Feeley XR, Schrenk M, Larsen D, Farland JC, Younes W, Dioxins M.: WHO’s tolerable daily intake (TDI) revisited. Chemosphere 2000; 40:1095- 1101.
  • 35. Yee SK, Chu SS, Xu YM, Choo PL.: Regulatory control of Chinese proprietary medicines in Singapore. Health Policy 2005; 71:133–149.
  • 36. Yoon E, Park K, Lee H, Yang JH, Lee C. Estimation of excess cancer risk on time-weighted lifetime average daily intake of PAHs from food ingestion. Hum Ecol Risk Assess 2007; 13:669–80.
  • 37. Zhian L, Ping Z, Murray BM, Hanping X, Ningyu L.: Health risk from heavy metals via consumption of food crops in the vicinity of Dabaoshan mine, South China. Sci. Total Env 2009; 407:1551-1561.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-5d927373-4b22-4e04-a52b-fc74ba4c20a2
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.