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2012 | 62 | 2 |

Tytuł artykułu

Determination of selected trace elements in dietary supplements containing plant materials

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The need for analytical methods enabling determining trace metals concentration in herbal medicinal products and dietary supplements has increased in recent years due to the globalisation of international market and also due to the risk of using herbs contaminated by heavy metals. To this end, an analytical method was developed and validated for the accurate determination of trace elements (As, Cd, Co, Cr, Cu, Mn, Pb, Sr, Zn) in products in the form of tablets or capsules, herbal teas and their aqueous infusions. The validation of described procedure of digestion samples and determination metals by ICP-MS method, shows its usability in determination of trace elements in herbal products. Recovery percentage based on CRMs ranged from 90.1% to 110.7%, and the precision of the method was below 3%. Out of all microelements determined, the highest concentration was found for Mn in herbal teas. The daily intake of Mn with infusions accounted for 53.3% and 126.4%, which corresponded to 41.7% and 98.9% of the AI values for adult women and men, respectively. The method was also used for quality control of the labelled level of chromium and zinc. In all analysed samples, the concentrations of cadmium and lead were below the EC maximum levels stipulated for Cd and Pb in dietary supplements.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

62

Numer

2

Opis fizyczny

p.97-102,fig.,ref.

Twórcy

autor
  • Department Natural Medicinal Products, Pharmaceutical Chemistry Department, National Medicines Institute, 30/34 Chelmska Street, 00-725 Warsaw, Poland
autor
autor
autor
autor

Bibliografia

  • 1. Baranowska I., Srogi K., Włochowicz A., Szczepanik K., Determination of heavy metal contents in samples of medicinal herbs. Pol. J. Environ. Stud., 2002, 11, 467–471.
  • 2. Blicharska E., Kocjan R., Błażewicz A., Determination of the content of iron, manganese, zinc, copper, cadmium and lead in the herbal teas. Bromat. Chem. Toksykol., 2007, 40, 145–151 (in Polish; English abstract).
  • 3. Chan K., Some aspects of toxic contaminants in herbal medicines. Chemosphere, 2003, 52, 1361–1371.
  • 4. Commission Regulation (EC) No 629/2008 of 2 July 2008, amending Regulation (EC) No 1881/2006 setting maximum levels for certain contaminants in foodstuffs.
  • 5. Dybczyński R., Danko B., Kulisa K., Maleszewska E., Polkowska--Motrenko H., Samczyński Z., Szopa Z.J., Preparation and preliminary certifi cation of two new Polish CRMS for inorganic trace analysis. J. Radioanal. Nucl. Chem., 2004, 259, 409–413.
  • 6. Expert Group on vitamins and minerals. Safe upper levels for vitamins and minerals. 2003. Available at: http://www.food.gov.uk/.
  • 7. Gasser U., Klier B., Kühn A.V., Steinhoff B., Current fi ndings on the heavy metal content in herbal drugs. Pharmeur. Sci. Notes, 2009, 1, 37–50.
  • 8. Gawęcki J., Żywienie człowieka. Podstawy nauki o żywieniu. 2010, PWN, Warszawa (in Polish).
  • 9. Kabata-Pendias A., Soil-plant transfer of trace elements – an environmental issue. Geoderma, 2004, 122, 143–149.
  • 10. Leśniewicz A., Jaworska K., Żyrnicki W., Macro- and micronutrients and their bioavailability in Polish herbal medicaments. Food Chem., 2006, 99, 670–679.
  • 11. Łozak A., Sołtyk K., Ostapczuk P., Fijałek Z., Determination of selected trace elements in herbs and their infusions. Sci. Total Environ., 2002, 289, 33–40.
  • 12. Martindale. The Complete Drug Reference, 2007, 35th edition, Pharmaceutical Press RPS Publishing, London, UK.
  • 13. Mojska H., Nalewczyńska M., Orłowski K., Szponar L., Herbs as foods components. Bromat. Chem. Toksykol., 2003, Supplement 5–12 (in Polish; English abstract).
  • 14. Ożarowski M., Krajewska-Patan A., Mrozikiewicz P.M., The interactions between herbal and synthetic drugs and possibility of appearance for interactions in Poland and in the world according to the pharmacoepidemiological information. Herba Pol., 2005, 51, 64–86 (in Polish; English abstract).
  • 15. Schilter B., Andersson C., Anton R., Constable A., Kleiner J., O’Brien J., Renwick A.G., Korver O., Smit F., Walker R., Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplements. Food Chem. Toxicol., 2003, 41, 1625–1649.
  • 16. Sobolewska D., Podolak I., Substances of natural origin used in therapy of obesity. Part I. Farmacja Polska, 2006, 13, 583–591 (in Polish; English abstract).
  • 17. Wang Z.Q., Cefalu W.T., Current concepts about chromium supplementation in type 2 diabetes and insulin resistance. Curr. Diab. Rep., 2010, 10, 145–151.
  • 18. WHO, World Health Organization. Trace element in human nutrition and health, 1996, Geneva.
  • 19. WHO, World Health Organization. Quality control methods for medicinal plant materials – Revised Draft Update. Working document QAS/05.131/Rev.1, WHO 2005, Geneva.

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Typ dokumentu

Bibliografia

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bwmeta1.element.agro-496c0117-194b-4a7a-8147-ec89c8a1e095
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