Twenty five years of azadirachtins (1986-2011)

• Autorzy: Hummel H.E. , Hein D. F. , Ley S. V. , Morgan E. D. , Kraus W. , Schmutterer H.
• Języki publikacji: EN

Abstrakty

EN

Azadirachtins are known as phagorepellent natural products from seeds of the neem tree Azadirachta indica A. Juss (Meliaceae), which impede the development of larval insects and sterilize adults. The labors of the past three decades ultimatively lead to a chemical structure, which has been unanimously but independently elaborated by German, British and American authors. This structure is in force ever since 1985/87 and was ultimately confirmed by Veitch & al. in Ley’s group in Cambridge, England, through total synthesis. Its 25th birthday is presently being celebrated. Marrangin (=Azadirachtin L) was discovered in Gießen and chemically identified by Kalinowski and colleagues. It occurs in seeds of the marrango tree, Azadirachta excelsa (Jack) Jacobs. In some insect species but also in mites like Tetranychus urticae, its biological activity is significantly superior to azadirachtin A. The value of these biorational compounds, with their very low vertebrate toxicity, and their low toxicity today is globally recognized. Quite recently, azadirachtin and analogues gain acceptance in veterinary and human medicine.

Słowa kluczowe

EN

azadirachtin; biopesticide; natural product; seed; neem tree; Azadirachta indica; marrango tree; Azadirachta excelsa; Tetranychus urticae; Epilachna varivestis

• Wydawca: -
• Czasopismo: Pestycydy
• Rocznik: 2011
• Numer: 1-4
• Opis fizyczny: p.49-56,fig.,ref.

Twórcy

autor

Hummel H.E.

• Chair of Organic Agriculture, Justus-Liebig-University Giessen, Germany

autor

Hein D. F.

autor

Ley S. V.

autor

Morgan E. D.

autor

Kraus W.

autor

Schmutterer H.

Bibliografia

• [1] Veitch G.E., Beckmann E., Burke B.J., Boyer A., Maslen S.L., Ley S.V., Angew. Chem. Int. Ed., 2007, 46, 1-5.
• [2] Butterworth J.H., Morgan E.D., J. Chem. Commun., 1968,1, 23-24.
• [3] Butterworth J.H., Morgan E.D., J. Insect Physiol., 1972,17, 969-977.
• [4] Ermel K., Kalinowski H.-O., SchmuttererH., J.Appl. Entomol., 1991,112,512-519.
• [5] Kalinowski H.-O., Ermel K., Schmutterer H., J. Liebigs Ann. Chem., 1993, 1033-1035.
• [6] Isman M.B., Annu. Rev. Entomol., 2006, 51, 45-66.
• [7] Koul O., Neem: A global perspective, in: Neem: today and in the new millennium, (O. Koul & S. Wahab, Eds.), Kluwer, Amsterdam, 2004, pp. 1-19.
• [8] Schmutterer H., (Ed.), The neem tree Azadirachta indicaA. Juss. and other meliaceous plants. Sources of unique natural products for integrated pest management, medicine, industry and other purposes, 2nd edition, Neem Foundation, 2002, Mumbai, First edition published 1995 by VCH, Weinheim, ISBN 3-527-30054-6.
• [9] Ishaaya I., Horowitz A.R., (Eds.), Biorational control of arthropod pests, Springer, 2009, pp. 408.
• [10] Schmutterer H., J. Insect Physiol., 1988, 34,713-719.
• [11] Schmutterer H., Annu. Rev. Entomol., 1990, 35, 271-297.
• [12] Schmutterer H., Niempräparate (Neem, Nim), in: (H. Schmutterer & J. Huber, Eds.), Natürliche Schädlingsbekämpfungsmittel, Ulmer Verlag, Stuttgart, 2005, pp. 171-196.
• [13] Hummel H.E., Hein D.F., Leithold G., Mitt. Dtsch. Ges. Allg. Angew. Ent., 2008, 16,487-490.
• [14] Kleeberg H., Strang R., Proc. 14th Neem workshop, Wetzlar, Germany, 2009.
• [15] Mordue (Luntz) A.J., The cellular actions of azadirachtin, in: (H. Schmutterer Ed.), The neem tree Azadirachta indica A. Juss. and other meliaceous plants, Neem Foundation, Mumbai. 2nd ed., 2002, pp. 266-274.
• [16] Rembold H., Entomologie Heute, 2004,16, 235-243.
• [17] Mordue A.J., Blackwell A., J. Insect Physiol., 1993, 39, 903-924.
• [18] Rembold H., Growth and metamorphosis, in: (H. Schmutterer, Ed.), The neem tree Azadirachta indica A. Juss. and other meliaceous plants, VCH, Weinheim, 2002, pp. 237-254.
• [19] Kraus W., Structure-activity relationships, in: (H. Schmutterer, Ed.), The neem tree Azadirachta indica A. Juss. and other meliaceous plants, 2005, VCH, Weinheim, pp. 73-74.
• [20] Broughton H.B., Ley S.V., Slawin A.M.Z., Williams D.J., Morgan E.D., J. Chem. Soc., Chem. Comm., 1986,46-47.
• [21] Bilton J.N., Broughton H.B., Jones P.S., Ley S.V., Lidert Z., Morgan E.D., Rzepa H.S., Sheppard R.N., Slawin A.M.Z., Williams D.J., Tetrahedron, 1987, 43, 2805-2815.
• [22] Kraus W., Bokel M., Bruhn A., Cramer R., Klaiber I., Klenk A., Nagl G., Pöhnl H., Sadlo H., Vogler B., Tetrahedron, 1987, 43, 2817-2830.
• [23] Turner C.J., Tempesta M.S., Taylor R.B., Zagorski M.G., Termini J.S., Schroeder D.R., Nakanishi K., Tetrahedron, 1987, 43, 2789-2803.
• [24] Hummel H.E., in: (Borovsky D., Spielman A., Eds.), Host regulated developmental mechanisms in vector arthropods, Proc. 2nd Symp., Vero Beach, Florida, 1989, 312-322.
• [25] Hummel H.E., Med. Fac. Landbouww. Rijksuniv. Gent., 1989, 54, 945-954.
• [26] National Research Council (U.S.), Board on Science and Technology for International Development, Neem: a tree for solving global problems: report of an ad hoc panel of the Board on Science and Technology for International Development, National Research Council, 1992, National Academy Press, Washington, D.C.
• [27] Talwar G.P., Raghuvanshi P., Jacobson M., 2002, in: The Neem Tree, (Schmutterer H., Ed.), 666-677.
• [28] Van der Esch S.A., Carnevali F., Amici A., Proc. 14th Neem workshop, Wetzlar, Germany, 2009, 31-40.
• [29] Ketkar C.M., Proc. 14th Neem workshop, Wetzlar, Germany, 2009, pp. 27-30.
• [30] Sombatsiri K., Ermel K., Schmutterer H., 2002, The Neem Tree, (Schmutterer H., Ed.), 745-760.
• [31] Hein D.F., Zur Biotechnik im Pflanzenschutz: Extraktion,Analytik und biologische Wirkungsweise ausgewählter Inhaltsstoffe von Azadirachta indica A. Juss. (Meliaceae), PhD Thesis, Fachbereich 09, Justus-Liebig-Universität Gießen, Fachverlag Köhler, Giessen, 1999, ISBN 3-922306-85-3.
• [32] Hummel H.E., Hein D.F., MaY., ItoY., Chou E.F., Med. Fac. Landbouww. Rijksuniv. Gent. 1997, 62,213-223.
• [33] Schütz S., Wengatz I., Goodrow M.H., Gee S.J., Hummel H.E., Hammock B.D., Development of an enzyme linked immunosorbent assay for azadirachtins, J. Agric. Food Chem., 1997, 45, 2363-2368.
• [34] Hummel H.E., Proc. Int. Neem Conf., Kunming, China, 2006, pp. 32-34.
• [35] Hummel H.E., Hein D.F., Leithold G., Pflanzenschutz im ökologischen Landbau -Probleme und Lösungsansätze, 12. Fachgespräch am 27. Sept 2009, ISSN: 0947- 8809, 141:19-27.
• [36] Allan E.J., Eeswara J.P., Johnson S., Mordue (Luntz) A.J., Morgan E.D., Stutchbury T., Pestic. Sci., 1994, 42, 147-152.
• [37] Wewetzer A., in: Proc. 5th Worksh., (Kleeberg H., Zebitz C.P.W., Eds.), Wetzlar, Germany, 1999, 243-249.
• [38] Morgan E.D., 2006, Proc. of the 2006 Int. Neem Conf., Kunming, China, 19-27.
• [39] Ascher K.R.S., Mazor M., Mansour F.A., in: The Neem Tree, (Schmutterer H., Ed.), 2002, 207-217.
• [40] Ketkar A.Y., Ketkar C.M., in: The Neem Tree, (Schmutterer H., Ed.), 2002,657-666.
• [41] Schmutterer H., Ermel K., Isman M.B., in: The Neem Tree, (Schmutterer H., Ed.),2002, 760-769.
• [42] Saxena R.C., in: The Neem Tree, (Schmutterer H., Ed.), 2002, 524-537.
• [43] Isman M.B., in: The Neem Tree, (Schmutterer H., Ed.), 2002, 378-401.
• [44] Siddiqui B.S., Rasheed M., Ali S.T., Ali S.K., Faizi S., Naqvi S.N.H, Tariq R.M., Proc. 2006 Int. Neem Conf., Kunming, China, 2006, pp. 70-77.
• [45] Schmutterer H., Huber J., (Eds.), Natüirliche Schädlingsbekämpfungsmittel, Ulmer Verlag, Stuttgart, 2005.
• [46] Ahmed S., in: The Neem Tree, (Schmutterer H., Ed.), 2002, 739-744.
• [47] Hellpap C., Förster P., Ahmed S., in: The Neem Tree, (Schmutterer H., Ed), 2002, 727-739.
• [48] Kraus W., Biologically active ingredients - azadirachtin and other triterpenoids (Part I), in: (H. Schmutterer, Ed.), The neem tree Azadirachta indica A. Juss and other meliaceous plants - Sources of unique natural products for integrated pest management, medicine, industry and other purposes, 2nd edition, Neem Foundation, Mumbai, 2002, pp. 39-78.
• [49] Martinéz-Villar E., Sáenz-de-Cabezón F.J., Moreno-Grijalba F., Marco V., Pérez-Moreno I., Exp. Appl. Acarol., 2005, 35, 215-222.
• [50] Duso C, Malagnini V., Pozzebon A., Castagnoli M., Liguori M., Simoni S., Biol. Control, 2008, 47, 16-21.
• [51] Sanguanpong U., Zur Wirkung ölhaltiger Niem- und Marrangosamenprodukte auf die Gemeine Spinnmilbe Tetranychus urticae Koch sowie Nebenwirkung auf ihren natürlichen Gegenspieler Phytoseiulus persimilis Athrias-Henriot, PhD Thesis, Fachbereich 09, Justus-Liebig-Universität Gießen, Fachverlag Köhler, 1992, Giessen.
• [52] Doll M., Schmutterer H., Mitt. Dtsch. Ges. Allg. Angew. Entomol., 1993,8, 775-780.