LC-MS/MS analysis of phenolic compounds and in vitro antioxidant potential of Stachys lavandulifolia Vahl.var. brachydon Boiss

• Autorzy: Bingol M.N. , Bursal E.
• Języki publikacji: EN

Abstrakty

EN

The identification and quantification of phenolic compounds of Stachys lavandulifolia Vahl. var. brachydon Boiss. by LC-MS/MS (Liquid Chromatography- tandem Mass Spectrometry) technique is the main purpose of the current study. The high concentrations of quinic acid (2534± 12 ppb) and chlorogenic acid (1882±92 ppb) were detected by LC-MS/MS.. Another goal of the study is to evaluate the antioxidant activities of both ethanol and aqueous extracts of the plant material. The antioxidant potentials of extracts were determined by using five different in vitro methods including; ABTS (2,2′-Azino-bis-3-ethylbenzothiazoline-6-sulfonic acid), DPPH(1,1- diphenyl-2-picryl-hydrazyl), FRAP (Ferric ions Reducing Antioxidant Power), CUPRAC (Cupric ions Reducing Antioxidant Power), and ferric thiocyanate methods. The results revealed that the aqueous and ethanol extracts of S. lavandulifolia leaves have good antioxidant potential with high phenolic content.

Słowa kluczowe

EN

Stachys lavandulifolia var.brachydon; phenolic compound; antioxidant potential; antiradical potential; LC-MS-MS technique; liquid chromatography-tandem mass spectrometry

• Wydawca: -
• Czasopismo: International Letters of Natural Sciences
• Rocznik: 2018
• Tom: 72
• Opis fizyczny: p.28-36,fig.,ref.

Twórcy

autor

Bingol M.N.

• Department of Biology, Graduate School of Natural and Applied Sciences, Mus Alparslan University, Mus, Turkey

autor

Bursal E.

• Department of Nursing, School of Health, Mus Alparslan University, Mus, Turkey

Bibliografia

• [1] B. Bhattacharjee, Taxonomic studies in Stachys: 2. A new infrageneric classification of Stachys L, Notes Roy. Bot. Gard. Edinburgh. 38(1) (1980) 65-96.
• [2] N. Özhatay, Ş. Kültür, Check-list of additional taxa to the Supplement Flora of Turkey III, Turkish Journal of Botany. 30(4) (2006) 281-316.
• [3] P. Davis, Flora of Turkey-VII, Edinburg University Press, 1982.
• [4] T. Miyase, R. Yamamoto, A. Ueno, Phenylethanoid glycosides from Stachys officinalis, Phytochemistry. 43(2) (1996) 475-479.
• [5] R. Yamamoto, T. Mıyase, A. Ueno, Stachyssaponins I-VIII, new oleanane-type triterpene saponins from Stachys riederi Chamisso, Chemical and Pharmaceutical Bulletin. 42(6) (1994) 1291-1296.
• [6] M. El-Ansari et al., Flavonoid constituents of Stachys aegyptiaca, Phytochemistry. 30(4) (1991) 1169-1173.
• [7] H. Skaltsa et al., Inhibition of prostaglandin E2 and leukotriene C4 in mouse peritoneal macrophages and thromboxane B2 production in human platelets by flavonoids from Stachys chrysantha and Stachys candida, Biological and Pharmaceutical Bulletin. 23(1) (2000) 47-53.
• [8] N. Maleki et al., Potent anti-inflammatory activities of hydroalcoholic extract from aerial parts of Stachys inflata on rats, Journal of Ethnopharmacology. 75(2-3) (2001) 213-218.
• [9] M. Couladis et al., Screening of some Greek aromatic plants for antioxidant activity, Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives. 17(2) (2003) 194-195.
• [10] O. Kilic, E. Bagci, Essential Oils of Three Ziziphora L. Taxa from Turkey and Their Chemotaxonomy, Asian Journal of Chemistry. 25(13) (2013).
• [11] E. Köksal et al., Assessment of antimicrobial and antioxidant activities of Nepeta trachonitica: analysis of its phenolic compounds using HPLC-MS/MS, Scientia Pharmaceutica. 85(2) (2017) 24.
• [12] A. Aras, E. Bursal, M. Dogru, UHPLC-ESI-MS/MS analyses for quantification of phenolic compounds of Nepeta nuda subsp. Lydiae, Journal of Applied Pharmaceutical Science. 6(11) (2016) 009-013.
• [13] A. Aras, M. Dogru, E. Bursal, Determination of antioxidant potential of Nepeta nuda subsp. lydiae, Analytical Chemistry Letters. 6(6) (2016) 758-765.
• [14] M. Ramezani, M. Hassanzadeh, D. Safdarabadi, Volatile constituents of Stachys lavandulifolia Vahl growing in Iran, ACGC Chem Res Commun. 15(15) (2002) 20-23.
• [15] K. Javidnia, F. Mojab, S. Mojahedi, Chemical constituents of the essential oil of Stachys lavandulifolia Vahl from Iran, Journal of Essential Oil Bearing Plants. 6(3) (2003) 174-178.
• [16] A. Aras et al., Identification of bioactive polyphenolic compounds and assessment of antioxidant activity of Origanum acutidens, International Letters of Natural Sciences. 66 (2017) 1-8.
• [17] İ. Gülçin, Antioxidant properties of resveratrol: a structure–activity insight, Innovative Food Science and Emerging Technologies. 11(1) (2010) 210-218.
• [18] E. Bursal, R. Boğa, Polyphenols analysed by UHPLC-ESI-MS/MS and antioxidant activities of molasses, acorn and leaves of oak (Quercus robur subsp. pedunculiflora), Progress in Nutrition. 20(1-S) (2018) 167-175.
• [19] M. Bener, F.B. Şen, R. Apak, Heparin-stabilized gold nanoparticles-based CUPRAC colorimetric sensor for antioxidant capacity measurement, Talanta 187 (2018) 148-155.
• [20] N. Turan et al., Spectroscopic, thermal and antioxidant properties of novel mixed ligand-metal complexes obtained from saccharinate complexes and azo dye ligand (mnppa), International Journal of Pharmacology. 12(2) (2016) 92-100.
• [21] N. Turan et al., Investigation of synthesis, structural characterization, antioxidant activities and thermal properties of Zn (II), Fe (II) and Mn (II) complexes with thiophene-carboxylate ligand, Journal of Chemistry and Biochemistry. 3(2) (2015) 13-29.
• [22] E. Bursal, Kinetic properties of peroxidase enzyme from chard (Beta vulgaris Subspecies cicla) leaves, International Journal of Food Properties. 16(6) (2013) 1293-1303.
• [23] E. Köksal et al., Antioxidant activity and polyphenol content of Turkish thyme (Thymus vulgaris) monitored by liquid chromatography and tandem mass spectrometry, International Journal of Food Properties. 20(3) (2017) 514-525.
• [24] E. Bursal, A. Aras, Ö. Kılıç, Evaluation of antioxidant capacity of endemic plant Marrubium astracanicum subsp. macrodon: Identification of its phenolic contents by using HPLC-MS/MS, Natural Product Research. (2018) 1-5.

Identyfikatory

DOI

10.18052/www.scipress.com/ILNS.72.28