Specyfika działania systemu antyoksydacyjnego nasienia knura

• Autorzy: Orzolek A. , Mietelska K. , Wysocki P.

Warianty tytułu

EN

Function of the antioxidant system in boar semen

• Języki publikacji: PL

Abstrakty

EN

An excessive generation of reactive oxygen species (ROS) in boar semen leads to a reduced motility and fertilizing ability of spermatozoa. Boar spermatozoa, because of a high content of polyunsaturated fatty acids (PUFAs) in their structure, are highly sensitive to lipid peroxidation (LPO). This process, induced by ROS generation, causes irreversible changes in the conformation and integrity of plasmalemma. The boar’s reproductive system includes a special antioxidant system consisting of enzymatic components and antioxidants of low molecular weight. The most active of antioxidant enzymes present in boar semen is superoxide dismutase (SOD). SOD transforms superoxide anion (O₂˙⁻) into hydrogen peroxide (H₂O₂). Because H₂O₂ can easily diffuse across the membranes, it is most harmful to boar spermatozoa. Given the low content of antioxidants of low molecular weight (e.g. L-gluthatione or L-ergothioneine) and the absence of catalase (CAT) activity in boar semen, there must be other mechanisms responsible for the scavenging of hydrogen peroxide and other ROS. This function is probably accomplished mainly by phospholipid hydroperoxide gluthatione peroxidase (PHGPx), enzymes of tioredoxin (TRX) and peroxiredoxin (PRDX) groups, as well as by paraoxonase type 1 and 2 (PON-1 and PON-2).

Słowa kluczowe

PL

trzoda chlewna; knury; nasienie; reaktywne formy tlenu; stres oksydacyjny; system antyoksydacyjny; enzymy antyoksydacyjne; aktywnosc enzymatyczna; potencjal antyoksydacyjny

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2016
• Tom: 72
• Numer: 05
• Opis fizyczny: s.291-297,bibliogr.

Twórcy

autor

Orzolek A.

• Katedra Biochemii i Biotechnologii Zwierząt, Wydział Bioinżynierii Zwierząt, Uniwersytet Warmińsko-Mazurski w Olsztynie, ul.Oczapowskiego 5, 10-719 Olsztyn

autor

Mietelska K.

• Katedra Biochemii i Biotechnologii Zwierząt, Wydział Bioinżynierii Zwierząt, Uniwersytet Warmińsko-Mazurski w Olsztynie, ul.Oczapowskiego 5, 10-719 Olsztyn

autor

Wysocki P.

• Katedra Biochemii i Biotechnologii Zwierząt, Wydział Bioinżynierii Zwierząt, Uniwersytet Warmińsko-Mazurski w Olsztynie, ul.Oczapowskiego 5, 10-719 Olsztyn

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