Parvalbumin and calbindin D28k in the dorsal raphe nucleus of the chinchilla

• Autorzy: Jaworska-Adamu J. , Szalak R.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to track the immunoreactivity of parvalbumin and calbindin D28k buffering proteins in neurons of the dorsal raphe nucleus DRN of the adult male chinchilla. The reaction of peroxidase-antiperoxidase (PAP) using specific antibodies against these proteins was performed. In most neurons, with the exception of small oval and medium-sized, stellate neurons, weak immunostaining of parvalbumin was observed. On the contrary, very intense immunostaining for calbindin D28k was shown in almost all neurons of the examined area. The results indicate a slightly different distribution in the nucleus dorsal raphe in the adult male chinchilla than in the rat. This shows that mainly calbindin D28k is included in the regulation of intracellular calcium ion concentration in the nucleus dorsal raphe of chinchilla.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2009
• Tom: 53
• Numer: 4
• Opis fizyczny: p.791-794,fig.,ref.

Twórcy

autor

Jaworska-Adamu J.

• Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-950 Lublin, Poland

autor

Szalak R.

• Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-950 Lublin, Poland

Bibliografia

• 1. Allers K.A., Sharp T.: Neurochemical and anatomical identification of fast- and slow-firing neurons in the rat dorsal raphe nucleus using juxtacellular labeling methods in vivo. Neuroscience 2003, 122, 193-204.
• 2. Azar S., Qian Z.-X., Knudsen G.M.: Non-serotoninergic dorsal and median raphe projection onto parvalbumin- and calbindin-containing neurons in hippocampus and septum. Neuroscience 2004, 124, 573-581.
• 3. Baker K.G., Halliday G.M., Tork I.: Cytoarchitecture of the human dorsal raphe nucleus. J Comp Neurol 1990, 301, 147-161.
• 4. Baker K.G., Halliday G.M., Hornung J.P., Geffen L.B., Cotton R.G., Tork I.: Distribution, morphology and number of monoamine-synthetizing and substance P- containing neurons in the human dorsal raphe nucleus. Neuroscience 1991, 42, 757-775.
• 5. Caillard O., Moreno H., Schwaller B., Llano I., Celio M.R., Marty A.: Role of the calcium binding protein parvalbumin in short-term synaptic plasticity. Proc Natul Acad Sci USA 2000, 97, 13372-13377.
• 6. Celio M.R.: Calbindin D-28k and parvalbumin in the rat central nervous system. Neuroscience 1990, 35, 375-475.
• 7. Charara A., Parent A.: Chemoarchitecture of the primate dorsal raphe nucleus. J Chem Neuroanatom 1998, 72, 111-127.
• 8. de Quidt M.E., Emson P.C.: Distribution of neuropeptide Y-like immunoreactivity in the central nervous system-II. Immunohistochemical analysis. Neuroscience 1981, 18, 545-618.
• 9. Hurnung J.-P.: The human raphe nuclei and the serotoninergic system. J Chem Neuroanatom 2003, 26, 331-343.
• 10. Łuszczewska-Sierakowska I.: Morphometrical analysis of neurons of the amygdaloideurrf s nucleus corpus amygdaloideum baso-lateralis. Medycyna Wet 2006, 62, 170-173.
• 11. Michelson K.A., Schmitz Ch., Steinbusch H.W.M.: The dorsal raphe nucleus from silver stainings to a role in depression. Brain Res Reviews 2007, 55, 329-342.
• 12. Otake K.: Cholecystokinin and substance P immunoreactive projections to the paraventricular thalamic nucleus in the rat. Neurosci Res 2005, 51, 383- 394.
• 13. Parvisi J., Damasio A.R.: Differential distribution of calbindin D28k and parvalbumin among functionally distinctive set of structures in the macaque brainstem. J Comp Neurol 2003, 462, 153-167.
• 14. Popović M., Caballero-Bleda M., Kadish I., Van Groen T.: Subfield and layer-specific depletion in calbindin- D28k, calretinin and parvalbumin immunoreactivity in the dentate gyrus of amyloid precursor protein/presenilin 1 transgenic mice. Neuroscience 2008, 115, 182-191.
• 15. Schwaller B., Meyer M., Schiffman S.: New functions for „old" proteins: the role of the calicum binding proteins calbindin D-28k, calretinin and parvalbumin, in cerebellar physiology. Studies with knockout mice. Cerebellum 2002, 1, 241-258.
• 16. Séquier J.M., Hunziker W., Andressen C., Celio M.R.: Calbindin D-28k protein and mRNA localization in the rat brain. European J Neurosci 2006, 2, 1118-1126.
• 17. Steinbusch H.W., Nieuwenhuys R., Verhofstad A.A., van der K.D.: The nucleus raphe dorsalis of the rat and its projection upon the caudatoputamen. A combined cytoarchitectionc, immunocytochemical and retrograde transport study. J Physiol (Paris) 1981, 77, 157-174.
• 18. Sternberger L.A.: Immunocytochemistry. Ed. John Wiley and Sons, New York, 1986.
• 19. Wawrzyniak-Gacek A., Pawelec J., Cybulska R.: Iron content in various types oligodendrocytes in the cortex frontal of rat's brains. Medycyna Wet 2006, 62, 957-959.