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2015 | 18 | 2 |

Tytuł artykułu

Comparison of IgE test results with intradermal skin tests for dust mites and storage mites in atopic dogs

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Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Atopic dermatitis is one of the most frequent allergic diseases in dogs. There are many methods of treating its symptoms but specific immunotherapy has recently gained high popularity. Before the application of specific immunotherapy, it is necessary to identify the allergens provoking the reaction of hypersensitivity in the selected animal. This raises a question about the method of allergen identification the medical practitioner decides to use in order to obtain the most credible result. The authors of the present study decided to compare the results of intradermal allergic tests and the results of an IgE screening test carried out using the FceRIa receptor method. The aim of the study was to compare the results of both tests directed to dust and storage mites. The study proves that in case of the IgE screening tests (for a group of allergens), the sensitivity is quite high (85 to 90.69%) but the specificity of these tests is insufficient (25 to 50%). In case of antibodies for the selected mites the sensitivity and specificity was too low (65.1 to 89.4% for the sensitivity, with only 14.2 to 33.3% for the specificity). Only in case of D. petronyssinus the results were higher with the sensitivity calculated at 65.1% and the specificity at 80%. The IgE screening test carried out using the FceRIa receptor method is reliable only in case of screening test for mites and the intradermal allergic test remains the gold standard for allergy testing.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

18

Numer

2

Opis fizyczny

p.351-356,ref.

Twórcy

autor
  • Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Wroclaw University of Environmental and Life Sciences, Pl. Grunwaldzki 47, 50-366 Wrocław, Poland
autor
  • Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Wroclaw University of Environmental and Life Sciences, Pl. Grunwaldzki 47, 50-366 Wrocław, Poland

Bibliografia

  • Arlian LG, Schumann RJ, Morgan MS, Glass RL (2003) Serum immunoglobulin E against storage mite allergens in dogs with atopic dermatitis. Am J Vet Res 64: 32-36.
  • Bensignor E, Carlotti DN (2002) Sensitivity patterns to house dust mites and forage mites in atopic dogs: 150 cases. Vet Dermatol 13: 37-42.
  • Bousquet J, Lockey R, Malling HJ (1998) Allergen immunotherapy: therapeutic vaccines for allergic diseases. J Allergy Clin Immunol 102: 558-562.
  • DeBoer DJ, Hill PB (1999) Serum immunoglobulin E concentrations in West Highland White Terrier puppies do not predict development of atopic dermatitis. Vet Deramtol 10: 275-281.
  • DeBoer DJ, Hillier A (2001) The ACVD task force on canine atopic dermatitis (XVI): laboratory evaluation of dogs with atopic dermatitis with serum-based „allergy" tests. Vet Immunol Immunopathol 81: 277-287.
  • Favrot C, Steffan J, Seewald W, Picco F (2010) A prospective study on the clinical features of chronic canine atopic dermatitis and its diagnosis. Vet Dermatol 21: 23-31.
  • Griffin CE, DeBoer DJ (2001) The ACVD task force on canine atopic dermatitis (XIV): clinical manifestations of canine atopic dermatitis. Vet Immunol Immunophathol 81: 255-269.
  • Halliwell R (2006) Revised nomenclature for veterinary allergy. Vet Immunol Immunopathol 114: 207-208.
  • Hill PB, Moriello KA, DeBoer DJ (1995) Concentrations of total serum IgE, IgA and IgG in atopic and parasitized dogs. Vet Immunol Immunopathol 44: 105-113.
  • Hill PB, DeBoer DJ (2001) The ACVD task force on canine atopic dermatitis (IV): environmental allergens. Vet Immunol 81: 169-186.
  • Hillier A, DeBoer DJ (2001) The ACVD task force on canine atopic dermatitis (XVII): intradermal testing. Vet Immunol Immunopathol 81: 289-304.
  • Keppel KE, Campbell KL, Zuckermann FA, Greeley EA, Schaeffer DJ, Husmann RJ (2008) Quantitation of canine regulatory T cell populations, serum interleukin-10 and allergen-specific IgE concentrations in healthy control dogs and canine atopic dermatitis patients receiving allergen-specific immunotherapy. Vet Immunol Im-munopathol 123: 337-344.
  • Koebrich S, Nett-Mettler C, Wilhelm S, Favrot C (2012) Intradermal and serological testing for mites in healthy beagle dogs. Vet Dermatol 23: 192-e39.
  • Masuda K, Sakaguchi M, Saito S, Deboer DJ, Yamashita K, Hasegawa A, Ohno K, Tsujimoto H. (2002) Seasonal atopic dermatitis in dogs sensitive to a major allergen of Japanese cedar (Cryptomeria japonica) pollen. Vet Dermatol 13: 53-59.
  • Olivry T, DeBoer DJ, Griffin CE, Halliwell RE, Hill PB, Hillier A, Marsella R, Sousa CA (2001) The ACVD task force on canine atopic dermatitis: forewords and lexicon. Vet Immunol Immunopathol 81: 143-146.
  • Olivry T, Marsella R, Iwasaki T, Mueller R (2007) Validation of CADESI-03, a severity scale for clinical trials enrolling dogs with atopic dermatitis. Vet Dermatol 18: 78-86.
  • Olivry T, Mueller R, Nuttall T, Favrot C, Prelaud P; International Task Force on Canine Atopic Dermatitis (2008) Determination of CADESI-03 thresholds for increasing severity levels of canine atopic dermatisis. Vet Dermatol 19: 115-119.
  • Olivry T, Saridomichelakis M, International Committee on Atopic Diseases of Animals (ICADA) (2013) Evidence-based guidelines for anti-allergic drug withdrawal times before allergen-specific intradermal and IgE serological test in dogs. Vet Dermatol 24: 255-e49.
  • Roque JB, O'Leary CA, Kyaw-Tanner M, Latter M, Mason K, Shipstone M, Vogelnest L, Duffy D (2011) High allergen-specific serum immunoglobulin E levels in nonatopic West Highland White Terriers. Vet Detmatol 22: 257-266.
  • Saridomichelakis MN, Marsella R, Lee KW, Esch RE, Far-maki R, Koutinas AF (2008) Assessment of cross-reactivity among five species of house dust and storage mites. Vet Dermatol 19: 67-76.
  • Scott DW, Miller WH, Griffin CE (2001) Canine Atopic Disease. In: Muller and Kirk's Small Animal Dermatology, 6th ed. WB Saunders, Philadelphia, pp 574-601.
  • Sture GH, Halliwell RE, Thoday KL, van den Broek AH, Henfrey JI, Lloyd DH, Mason IS, Ferguson E (1995) Canine atopic disease: the prevalence of positive intradermal skin test at two sites in the north and south of Great Britain. Vet Immunol Immunopathol 44: 293-308.
  • Tarpataki N, Papa K, Reiczigel J, Vajdovich P, Vorosi K (2006) Prevalence and features of canine atopic dermatitis in Hungary. Acta Vet Hun 54: 353-366.
  • Wassom DL, Grieve RB (1998) In vitro measurement of canine and feline IgE: a revive of FceR1a-based assays for detection of allergen-reactive IgE. Vet Dermatol 9: 173-178.

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Bibliografia

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