Sensory experience influences magnitude of responses in the rat visual system

• Autorzy: Zeber K. , Foik A. , Urban P. , Porowska A. , Waleszczyk W.J.
• Języki publikacji: EN

Abstrakty

EN

BACKGROUND AND AIMS: The aim of this study was to evoke plasticity in chosen structures of the rat visual system by visual training (sensory experience). METHODS: Local field potentials (LFPs) were recorded from the rat superior colliculus (SC) and primary visual cortex (VCx) of contralateral hemisphere to stimulated eye. LFPs were collected before, during and after visual training. The training consisted of series of 300 repetitions of light flashes separated by 2–3 s intervals. The series of stimuli were presented to the one eye every 15 minutes through three hours. RESULTS: Our data show that visual stimulation significantly enhanced magnitude of visual responses in both recorded structures. A significant increase of visual responses occurred after first hour of training (four stimulating series) both in SC and VCx. The largest increase of VEP amplitudes in the SC was observed after the third hour of stimulation and that was significantly different compared to the first and the second hour of training. Regarding the VCx, advanced alterations of VEPs were observed already after the first hour and then the amplitudes of cortical VEPs remained at a similar level to the end of training. To examine whether the above changes did not result from the changes in the level of anesthesia and global brain state, we considered the VCx LFP power ratio in delta (1–4 Hz) and beta (13–30 Hz) frequency range of the signal recorded for 30 s before each series of stimulation. Changes in the course of delta/beta ratio were similar for all channels in VCx during three hours of visual training and didn’t correlate with increase of VEPs. CONCLUSIONS: Repetitive visual stimulation enhance responses in the visual system, both at cortical and subcortical level, independently of the global brain state, thus may constitute a fundamental approach to improve visual functions. Supported by ERA-NET Neuron project REVIS.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2015
• Tom: 75
• Numer: Supl.
• Opis fizyczny: p.S96-S97

Twórcy

autor

Zeber K.

• Neurobiology of Vision Laboratory, Department of Neurophysiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland

autor

Foik A.

• Neurobiology of Vision Laboratory, Department of Neurophysiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland

autor

Urban P.

• Neurobiology of Vision Laboratory, Department of Neurophysiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland

autor

Porowska A.

• Neurobiology of Vision Laboratory, Department of Neurophysiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland

autor

Waleszczyk W.J.

• Neurobiology of Vision Laboratory, Department of Neurophysiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland