Effect of fowl adenovirus on replication of vaccine strain of Marek’s disease virus in chickens

• Autorzy: Niczyporuk J.S. , Wozniakowski G. , Samorek-Salamonowicz E. , Czekaj H.
• Języki publikacji: EN

Abstrakty

EN

The aim of the study was to determine the effect of field strain, serotype 7 (FAdV-7 JN-5/10), of fowl adenovirus infection on the replication of Rispens/CVI988 strain of Marek's disease virus. Ninety one-day-old SPF chickens were divided into six groups. The chickens from group I were vaccinated against Marek's disease (MD) and 24 h later infected with the adenovirus; chickens from group II were vaccinated and infected simultaneously; chickens from group III were infected with the adenovirus and 24 h after the infection vaccinated against MD. The chickens from groups IV-VI were: control of infection (IV), control of vaccination (V), and neither vaccinated nor infected (VI). After 3, 7, 14, 21, and 28 d post infection, the number of copies of pp38 gene of Rispens strain and hexon gene of FAdV strain was determined in the bursa of Fabricius and liver using real-time PCR. The results indicated that in all cases the replication of Rispens strain was reduced to about 1.0 log₁₀- 3.5 log₁₀ in chickens infected with the adenovirus and vaccinated against MD compared with the chickens only vaccinated. Sixty-three one-day-old SPF chickens infected with adenovirus and vaccinated against MD were challenged with vv MD virus field strain. The protection index in this experiment was 55.6%-77.8%.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2013
• Tom: 57
• Numer: 4
• Opis fizyczny: p.467-472,fig.,ref.

Twórcy

autor

Niczyporuk J.S.

• Department of Poultry Viral Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Wozniakowski G.

• Department of Poultry Viral Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Samorek-Salamonowicz E.

• Department of Poultry Viral Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Czekaj H.

• Department of Poultry Viral Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland

Bibliografia

• 1. Baigent S.J., Petherbridge L.J., Howes K., Smith L.P., Currie R.J., Nair V.K.: Absolute quantitation of Marek's disease virus genome copy number in chicken feather and lymphocyte samples using real-time PCR. J Virol Method 2005, 123, 53-64.
• 2. Chiocca S., Kurzbauer R., Schaffner G., Baker A., Mautner V.: The complete DNA sequence and genomic organization of the avian adenovirus CELO. J Virol 1996, 70, 2939-2949.
• 3. Echavarria M.: Adenoviruses in immunocompromised hosts. Clin Microbiol Reviews 2008, 21, 704- 715.
• 4. Gabriel A.L., Masuda E.K., Ramos A.T., Inkelmann M.A., Azambuja E., Graca D.L.: Canine adenovirus type-2 and canine distemper virus pulmonary co-infection in two Chow-Chow puppies with Candida sp esophagitis. Brasil J Vet Pathol 2008, 1, 47-51.
• 5. Geanesh K., Suryanarayana V.V., Raghavan R.: Detection of fowl adenovirus associated with hydropericardium hepatitis syndrome by polymerase chain reaction. Vet Res Com 2002, 26, 73-80.
• 6. Grgić H., Philippe C., Ojkić D., Nagy E.: Study of vertical transmission of fowl adenoviruses. Can J Vet Res 2006, 70, 230-233.
• 7. Hoerr F.J.: Clinical aspects of immunosuppression in poultry. Avian Dis 2010, 54, 2-15.
• 8. Ison M.G.: Adenovirus infections in transplant recipients. Emerging Infect 2006, 43, 331-339.
• 9. Jeurissen S.H.M., Boer G.F.: Chicken anaemia virus influences the pathogenesis of Marek's disease in experimental infections depending on the dose of Marek's disease virus. Vet Quart 1993, 14, 81-84.
• 10. Lappalainen S., Ylitalo S., Arola A., Halkosalo A., Rasanen S., Vesikari T.: Simultaneous presence of human herpesvirus 6 and adenovirus infections in intestinal intussusception of young children. Acta Pediat 2012, 101, 663-670.
• 11. McConnell B.A., Fitzgerald A.S.: Group I Adenovirus Infections. Disease of Poultry, edited by Y.M. Saif, Blackwell Publishing Company, Australia 2008, pp. 252-286.
• 12. Naeem K., Niazi T., Malik S.A., Cheema A.H.: Immunosuppressive potential and pathogenicity of avian adenovirus isolate involved in hydropericardium syndrome in broilers. Avian Dis 1995, 39, 723-728.
• 13. Niczyporuk J.S., Woźniakowski G., Samorek-Salamonowicz E., Czekaj H.: Effect of fowl adenovirus (FAdV-7) infection on the replication of turkey herpesvirus FC126 in chicken embryo fibroblast cultures. Bull Vet Inst Pulawy 2012, 56, 441 -446.
• 14. Okuda Y., Ono M., Shibata I., Sato S., Akashi H.: Comparison of the polymerase chain reaction restriction fragment length polymorphism pattern of the fiber gene and pathogenicity of serotype -1 fowl adenovirus isolates from gizzard erosions and from feces of clinically healthy chickens in Japan. J Vet Diagn Invest 2006, 18, 162-167.
• 15. Otaki Y., Nunoya T., Tajima M., Kato A., Nomura Y.: Depression of vaccinal immunity to Marek's disease by infection with chicken anemia agent. Avian Pathol 1988. 17, 333-347.
• 16. Saifuddin M., Wilks C.R.: Effects of fowl adenovirus infection on the immune system of chickens. J Comp Pathol 1992, 107, 285-294.
• 17. Samorek-Salamonowicz E.: Characteristic of adenovirus strains isolated from birds in Poland with the consideration on their influence on the replication of herpesvirus turkey strain. Thesis, UMCS Lublin. 1986.
• 18. Samorek-Salamonowicz E., Kozdruń W., Czekaj H.: The influence of reovirus infection on the efficiency of vaccinations against Marek's disease. Med Weter 1999, 55, 455-460.
• 19. Schat K.A., Nair V.: Marek's Disease. Disease of Poultry, edited by Y.M. Saif, Blackwell Publishing Company, Australia 2008, pp. 452-514.
• 20. Schonevville E., Singh A., Gobel T.W., Gerner W., Saalmuller A., Hess M.: Fowl adenovirus (FAdV) serotype 4 causes depletion of B and T cells in lymphoid organs in specific pathogen-free chickens following experimental infection. Vel Immunol Immunopathol 2008, 121, 130-139.
• 21. Shivachandra S.B., Sah R.L., Singh S.D., Kataria J.M., Manimaran K.: Immunosuppression in broiler chicks fed aflatoxin and inoculated with fowl adenovirus serotype-4 (FAdV-4) associated with hydropericardium syndrome. Vet Res Comm 2003, 27, 39-51.
• 22. Singh A., Grewal G.S., Maiti N.K., Oberoi M.S.: Effect of fowl adenovirus-1 (IBH isolate) on humoral and cellular immune competency of broiler chicks. Com Immnunol Micobiol Infect Dis 2006, 29, 315-321.
• 23. Toro H., Gonzalez C., Cerda L., Hess M., Reyes E., Geisse C.: Chicken anemia virus and fowl adenoviruses association to induce the inclusion body hepatitis/hydropericardium syndrome. Avian Dis 2000, 58, 44-51.

Identyfikatory

DOI

10.2478/bvip-2013-0081