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Czasopismo

2010 | 69 | 1 |

Tytuł artykułu

Blue nevus of the endocervix

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The mucosa of the uterine cervix is normally devoid of melanocytes; therefore, melanin-containing lesions are very rare in this site. A new case of a common blue nevus in the cervix of a 57-year-old woman is reported. The lesion was an incidental finding in a total hysterectomy specimen performed for atypical endometrial hyperplasia. Gross and histological examination revealed minute dark macula on the mucosa of the posterior aspect of the endocervical canal, composed of loose conglomerates of spindle-shaped and dendritic cells located superficially within the stroma, containing multiple brownish granules, which exhibited positive immunostaining for HMB45 and melan A. Although the blue nevi seem to be lesions of low clinical significance, they require careful differential diagnosis with malignant melanoma, especially in scanty endocervical curettage or cervical biopsy specimens. (Folia Morphol 2010; 69, 1: 62–64)

Wydawca

-

Czasopismo

Rocznik

Tom

69

Numer

1

Opis fizyczny

p.62-64,fig.,ref.

Twórcy

autor
  • Department of Clinical Pathomorphology, Medical University of Lublin, Jaczewskiego 8, 20-059 Lublin, Poland
autor
  • Department of Clinical Pathomorphology, Medical University of Lublin, Jaczewskiego 8, 20-059 Lublin, Poland
autor
  • Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, Lublin, Poland
autor
  • Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, Lublin, Poland

Bibliografia

  • 1. Barauah J, Roy KK, Kumar S, Kumar L (2009) A rare case of primary malignant melanoma of cervix. Arch Gynecol Obstet, 280: 453–456.
  • 2. Calonje E, Blessing K, Glusac E, Strutton G (2006) Blue naevi. In: LeBoit PE, Burg G, Weedon D, Sarasi A eds. World Health Organisation Classification of Tumors. Pathology and genetics of skin tumors. IARCPress, Lyon, pp. 95–99.
  • 3. Cid JM (1959) La pigmentation melanique de l’endocervix: un argumento visceral neurogenique. Ann Anat Pathol (Paris), 4: 617–628.
  • 4. Craddock KJ, Bandarchi B, Khalifa MA (2007) Blue nevi of the Müllerian tract: case series and review of the literature. J Low Genit Tract Dis, 11: 284–289.
  • 5. Deppisch LM (1983) Cervical melanosis. Obstet Gynecol, 62: 525–526.
  • 6. Donofrio V, Terracciano LM, Boscaino A, De Rosa G, Buffa D (1992) Blue nevus of the uterine cervix. Pathologica, 83: 539–545.
  • 7. Hagiwara T, Kaku T, Kobayashi H, Hirakawa T, Nakano H (2005) Coexisting vulvar malignant melanoma and blue nevus of the cervix. Gynecol Oncol, 99: 519–520.
  • 8. Handa U, Mohan H, Garg S (2007) Incidental detection of pigmented lesions in the cervix. Aust N Z J Obstet Gynaecol, 47: 254–255.
  • 9. Kudo M, Nagayama T, Miura M, Fukunaga N (1983) Blue nevus of the uterine cervix. An ultrastructural study of two cases. Arch Pathol Lab Med, 107: 87–90.
  • 10. Patel DS, Bhagavan BS (1985) Blue nevus of the uterine cervix. Hum Pathol, 16: 79–86.
  • 11. Schneider V, Zimberg ST, Kay S (1981) The pigmented portio: benign lentigo of the uterine cervix. Diagn Gynecol Obstet, 3: 269–272.
  • 12. Uehara T, Izumo T, Kishi K, Takayama S, Kasuga T (1991) Stromal melanocytic foci (”blue nevus”) in step sections of the uterine cervix. Acta Pathol Jpn, 41: 751–756.
  • 13. Uehara T, Takayama S, Takemura T, Kasuga T (1991) Foci of stromal melanocytes (so-called blue naevus) of the uterine cervix in Japanese women. Virchows Arch A Pathol Anat Histopathol, 418: 327–331.
  • 14. Zevallos-Giampietri EA, Barrionuevo C (2004) Common blue nevus of the uterine cervix: case report and review. Appl Immunohistochem Mol Morphol, 12: 79–82.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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