Food as a source of exposure to nickel

• Autorzy: Mania M. , Rebeniak M. , Postupolski J.
• Języki publikacji: EN

Abstrakty

EN

According to the European Food Safety Authority (EFSA), food is the main source of nickel intake by the general population. Based on the risk assessment, EFSA determined the tolerable daily intake of this element (TDI) from all sources at the level of 2.8 μg/kg body weight, which is for an adult 196 μg, while for a child 56 μg. The Benchmark Dose Lower Confidence Limit (BMDL₁₀) associated with dermatitis at 1.1 μg/kg body weight was also determined as well as the Margin of Exposure (MOE). Nickel intake in the Member States varies and depends on consumption habits. CONTAM Panel of EFSA considered the unlikely possibility of developing cancers related to the intake of nickel with food. According to experts, other harmful effects on the human body are more often identified. An additional aspect requiring further investigations that will allow an actual estimation of exposure associated with intake of this element by various groups of population is the issue of nickel absorption in the human body. The review of the EFSA opinion on the request of the European Commission planned in the near future based on the collected data as part of the action of the Commission Recommendation (EU) 2016/1111 on monitoring the presence of nickel in food will contribute to taking appropriate actions related to consumer protection, including the most vulnerable groups of population.

PL

Według Europejskiego Urzędu ds. Bezpieczeństwa Żywności (EFSA), głównym źródłem pobrania niklu przez populację generalną jest żywność. Na podstawie dokonanej oceny ryzyka EFSA wyznaczył wartość tolerowanego dziennego pobrania tego pierwiastka (Tolerable Daily Intake TDI) ze wszystkich źródeł na poziomie 2,8 μg/kg masy ciała, co stanowi dla osoby dorosłej 196 μg, natomiast dla dziecka 56 μg. Określono również najniższą dawkę wyznaczającą (Benchmark Dose Lower Confidence Limit) – BMDL₁₀ związaną z występowaniem zapaleń skórnych na poziomie - 1,1 μg/kg masy ciała oraz wyznaczono wartość marginesu narażenia (Margin of Exposure – MOE). Pobranie niklu w państwach członkowskich jest zróżnicowane i zależne od nawyków żywieniowych. Panel CONTAM EFSA uznał za mało prawdopodobną możliwość powstawania nowotworów związanych z pobraniem niklu z żywnością. Zdaniem ekspertów znacznie częściej identyfikowane są inne efekty szkodliwe na organizm człowieka. Dodatkowym aspektem wymagającym dalszych badań, który pozwoli na rzeczywiste oszacowanie narażenia związanego z pobraniem tego pierwiastka przez różne grupy populacji, jest kwestia wchłaniania niklu w organizmie człowieka. Planowana w najbliższym czasie na wniosek Komisji Europejskiej rewizja opinii EFSA, w oparciu o zgromadzone dane w ramach zalecenia Komisji (UE) nr 2016/1111 w sprawie monitorowania obecności niklu w żywności, przyczyni się do podjęcia odpowiednich działań związanych z ochroną konsumentów, w tym najbardziej wrażliwych grup populacji.

• Wydawca: -
• Czasopismo: Roczniki Państwowego Zakładu Higieny
• Rocznik: 2019
• Tom: 70
• Numer: 4
• Opis fizyczny: p.393-399,ref.

Twórcy

autor

Mania M.

• Department of Food Safety, National Institute of Public Health-National Institute of Hygiene, 24 Chocimska str., 00-791 Warsaw, Poland

autor

Rebeniak M.

• Department of Food Safety, National Institute of Public Health-National Institute of Hygiene, 24 Chocimska str., 00-791 Warsaw, Poland

autor

Postupolski J.

• Department of Food Safety, National Institute of Public Health-National Institute of Hygiene, 24 Chocimska str., 00-791 Warsaw, Poland

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Identyfikatory

DOI

10.32394/rpzh.2019.0090