Evaluation of IL-2, IL-4 and IL-10 levels in patients with giardiosis

• Autorzy: Khalaf M.M. , Hussein M.H. , Hafedh A.A.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to determine IL-2, IL-4 and IL-10 levels, in patients with giardiosis and to compare their interleukins levels with healthy controls. A total of 375 patients (211 males, 164 females) in Thi-Qar Province, southern of Iraq were examined. Twenty-four (16 males, 8 females) patients confirm to have giardiosis and 20 healthy control group were withdrawn (5) ml of venous blood to conduct immunological tests to determine the quantitative for level of IL-2, IL-4 and IL-10 in a manner (ELISA). The result showed, the overall infection rate of G. lamblia was 6.40%, according to gender, higher infection rate was recorded in males 7.58% compared to the females rate 4.87% no significant differences were observed between gender. The highest rates of giardiosis observed in age group (30–45), which reached 7.04% and there is no significant difference showed in the infection of different ages under study (P≤0.05). The results showed a significant increases in the level of interleukins and the amount of IL-2, IL- 4 and IL-10 in patients (26.90, 17.43 and 14.71), respectively, was higher than those of healthy control (13.32, 10.25 and 10.55). The conclusion of this study demonstrated that the rate of infection was higher in males than in females and the age group (30–45) have the highest infection rates. The levels of interleukins (IL-2, IL-4 and IL10) were increased in the infected patient when compared to healthy persons, from this, we can deduce that pro-inflammatory and antiinflammatory interleukins have an important role in the infection of Giardia lamblia.

• Wydawca: -
• Czasopismo: Annals of Parasitology
• Rocznik: 2021
• Tom: 67
• Numer: 4
• Opis fizyczny: p.697-702,ref.

Twórcy

autor

Khalaf M.M.

• Thi-Qar Education Directorate, Thi-Qar, Iraq

autor

Hussein M.H.

• College of Science, Thi-Qar University, Thi-Qar, Iraq

autor

Hafedh A.A.

• College of Science, Thi-Qar University, Thi-Qar, Iraq

Identyfikatory

DOI

10.17420/ap6704.386