Antibiotic resistance genes and virulence factors in Enterococcus faecium and Enterococcus faecalis from diseased farm animals: pigs, cattle and poultry

• Autorzy: Seputiene V. , Bogdaite A. , Ruzauskas M. , Suziedeliene E.
• Języki publikacji: EN

Abstrakty

EN

Eighty enterococcal isolates (E. faecium, n=38, E. faecalis, n=42) from diseased farm animals (swine, cattle, poultry) in Lithuania have been studied for the prevalence of antibiotic resistance and for resistance and virulence genetic determinants. 86% of E. faecium and 71% of E. faecalis isolates were multidrug resistant (resistant to three or more unrelated antibiotics). Resistance to aminoglycosides, tetracycline and erythromycin was found most frequently in both species (61%, 69%) and was linked to aph(3’)-IIIa, aac(6’)-Ie-aph(2”)-Ia, ant(6)-Ia (aminoglycoside resistance), tetM, tetL (tetracycline resistance), ermA, ermB (erythromycin resistance) gene combinations, which were supplemented with chloramphenicol resistance genes catA7, catA8 (E. faecalis) and catA9 (E. faecium). All E. faecalis isolates harboured genes coding for virulence factors agg, esp, fsr gelE alone or in combinations with the high prevalence of esp gene in isolates from cattle (63%) and pigs (79%). The origin- dependent incidence of agg gene variants prgB and asp1 was observed. The results indicate the existence of a large pool of potentially virulent and multidrug resistant E. faecalis in diseased farm animals posing risk to humans.

Słowa kluczowe

EN

antibiotic resistance; resistance gene; virulence factor; Enterococcus faecium; Enterococcus faecalis; farm animal; animal disease; pig; cattle; poultry

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2012
• Tom: 15
• Numer: 3
• Opis fizyczny: p.431-438,ref.

Twórcy

autor

Seputiene V.

• Department of Biochemistry and Biophysics, Faculty of Natural Sciences, Vilnius University, M.K.Ciurlionio 21, Vilnius LT-03101, Lithuania

autor

Bogdaite A.

autor

Ruzauskas M.

autor

Suziedeliene E.

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