Leczenie ostrej toksoplazmozy u zwierząt eksperymentalnie zarażonej szczepem RH Toxoplasma gondii

• Autorzy: Sikorski R.

Warianty tytułu

EN

The treatment of acute toxoplasmosis in animals infected experimentally with Toxoplasma gondii

RU

Lechenie ostrogo toksoplazmoza u zhivotnykh ehksperimental'no inficirovannykh stammom RH Toxoplasma gondii

• Języki publikacji: PL

Abstrakty

EN

Mice were infected with RH Toxoplasma gondii by intraperitoneal injection of 0.4 ml of protozoa containing exudate; the drugs were administered by oral or intraperitoneal route for 10 days after the infection, the survival rate of animals constituting a criterion of efficiency. Among the applied drugs, daraprim proved to be the most efficient, since given in the doses of 0.025-0.5 daily it was found to increase the survival time by 3-30 days; supronal in the dosis of 10.0-13.3 mg caused an increase by 15-16 days, and orisol in 1.5-2.0 mg prolonged the survival rate only by 4 days. Far better results were obtained with the combination of 2 drugs. The strongest action was exerted by daraprim and dosulphin (0.025 mg + 1.5 mg) increased the survival rate by 56 days, then dosulphin and orisol (1.5 mg + 2.0 mg), dosulphin and supronal (1.5 mg + 10.0 mg) and daraprim and supronal (0.025 mg + 10.0 mg) resulting in a 37-day increase. Less efficient were orisol + supronal (21-day increase) and daraprim + orisol (by 23 days).

• Wydawca: -
• Czasopismo: Wiadomości Parazytologiczne
• Rocznik: 1964
• Tom: 10
• Numer: 4-5
• Opis fizyczny: s.371-373,tab.

Twórcy

autor

Sikorski R.

• I Klinika Położnictwa i Chorób Kobiecych, Akademia Medyczna w Lublinie, Lublin
• Zakład Parazytologii Wiejskiej, Instytut Medycyny Pracy i Higieny Wsi w Lublinie, Lublin