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2013 | 62 | 1 |

Tytuł artykułu

Active stable maintenance functions in low copy-number plasmids of Gram-positive bacteria. I. Partition systems

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Low copy number plasmids cannot rely on the random segregation during bacterial cell division. To be stably maintained in the population they evolved two types of mechanisms (i) partition systems (PAR) that actively separate replicated plasmid molecules to the daughter cells and (ii) toxin-andidote systems (TA) that act after cell division to kill plasmid-less cells. Our knowledge of partition systems has been based mainly on analysis of plasmids from Gram-negative bacteria. Now, numerous partition systems of plasmids from Gram-positive bacteria have also been characterized and make significant contribution to our understanding of these mechanisms.

Wydawca

-

Rocznik

Tom

62

Numer

1

Opis fizyczny

p.3-16,fig.,ref.

Twórcy

autor
  • Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland
  • Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland

Bibliografia

  • Akhtar P., S.P. Anand, S.C. Watkins and S.A. Khan. 2009. The tubulin-like RepX protein encoded by the pXO1 plasmid forms polymers in vivo in Bacillus anthracis. J. Bacteriol. 191: 2493–2500.
  • Akhtar P. and S.A. Khan. 2012. Two independent replicons can support replication of the anthrax toxin-encoding plasmid pXO1 of Bacillus anthracis. Plasmid 67: 111–117.
  • Anand S.P., P. Akhtar, E. Tinsley, S.C. Watkins and S.A. Khan. 2008. GTP-dependent polymerization of the tubulin-like RepX replication protein encoded by the pX01 plasmid of Bacillus anthracis. Mol. Microbiol. 67: 881–890.
  • Austin S. and K. Nordström. 1990. Partition-mediated incompatibility of bacterial plasmids. Cell. 60: 351–354.
  • Aylett C.H.S., Q. Wang, K.A. Michie, L.A. Amos and J. Löewe. 2010. Filament structure of bacterial tubulin homologue TubZ. Proc. Natl. Acad. Sci. USA 107: 19766–19771.
  • Aylett C.H.S. and J. Löwe. 2012. Superstructure of the centromeric complex of TubZRC plasmid partitioning systems. Proc. Natl. Acad. Sci. USA 109: 16522–16527.
  • Becker E., N.C. Herrera, F.Q. Gunderson, A.I. Derman, A.L. Dance J. Sims, R.A. Larsen and J. Pogliano. 2006. DNA segregation by the bacterial actin AlfA during Bacillus subtilis growth and development. EMBO J. 25: 5919–5931.
  • Beggs M.L., J.T. Crawford and K.D. Eisenach. 1995. Isolation and sequencing of the replication region of Mycobacterium avium plasmid pLR7. J. Bacteriol. 177: 4836–40.
  • Benachour A., J. Frère and G. Novel. 1995. pUCL287 plasmid from Tetragenococcus halophila (Pediococcus halophilus) ATCC 33315 represents a new theta-type replicon family of lactic acid bacteria. FEMS Microbiol. Lett. 128: 167–75.
  • Berg T., N. Firth, S. Apisiridej, A. Hettiaratchi, A. Leelaporn, and R.A. Skurray. 1998. Complete nucleotide sequence of pSK41: Evolution of staphylococcal conjugative multiresistance plasmids. J. Bacteriol. 180: 4350–4359.
  • Berry C., S. O’Neil, E. Ben-Dov, A.F. Jones, L. Murphy, M.A. Quail, M.T.G. Holden, D. Harris, A. Zaritsky and J. Parkhill. 2002. Complete sequence and organization of pBtoxis, the toxincoding plasmid of Bacillus thuringiensis subsp israelensis. Appl. Environ. Microbiol. 68: 5082–5095.
  • Bignell C. and C.M. Thomas. 2001. The bacterial ParA-ParB partitioning proteins. J. Biotech. 91: 1–34.
  • Brennan R.G. and B.W. Matthews. 1989. The helix-turn-helix DNA binding motif. J. Biol. Chem. 264: 1903–1906.
  • Bruand C., S.D. Ehrlich and L. Jannière. 1991.Unidirectional theta replication of the structurally stable Enterococcus faecalis plasmid pAM beta 1. EMBO J. 10: 2171–2177.
  • Bruand C., E. Le Chatelier, S.D. Ehrlich and L. Jannière. 1993. A fourth class of theta-replicating plasmids: the pAM beta 1 family from gram-positive bacteria. Proc. Natl. Acad. Sci. USA 90: 11668–11672.
  • Burkhard P., J. Stetefeld and S.V. Strelkov. 2001. Coiled coils: a highly versatile protein folding motif. Trends. Cell. Biol. 11: 82–88.
  • Byrne M.E., M.T. Gillespie and R.A. Skurray. 1990. Molecular analysis of a gentamicin resistance transposonlike element on plasmids isolated from North American Staphylococcus aureus strains. Antimicrob. Agents Chemother. 34: 2106–13.
  • Ceglowski P., A. Boitsov, S. Chai and J.C. Alonso. 1993. Analysis of the stabilization system of pSM19035-derived plasmid pBT233 in Bacillus subtilis. Gene 136: 1–12.
  • Chen Y. and H.P. Erickson. 2008. In vitro assembly studies of FtsZ/tubulin-like proteins (TubZ) from Bacillus plasmids – evidence for a capping mechanism. J. Biol. Chem. 283: 8102–8109.
  • Clewell D.B. 1993. Bacterial sex pheromone-induced plasmid transfer. Cell. 73: 9–12.
  • Clewell D.B. 2007. Properties of Enterococcus faecalis plasmid pAD1, a member of a widely disseminated family of pheromone-responding, conjugative, virulence elements encoding cytolysin. Plasmid. 58: 205–27.
  • Clewell D.B., P.K. Tomich, M.C. Gawron-Burke, A.E. Franke, Y. Yagi and F.Y. An. 1982. Mapping of Streptococcus faecalis plasmids pAD1 and pAD2 and studies relating to transposition of Tn917. J. Bacteriol. 152: 1220–1230.
  • Das N. and D.K. Chattoraj. 2004. Origin pairing (‘handcuffing’) and unpairing in the control of P1 plasmid replication. Mol. Microbiol. 54: 836–849.
  • de la Hoz A.B., F. Pratto, R. Misselwitz, C. Speck, W. Weihofen, K. Welfe, W. Saenger, H. Welfe and J.C. Alonso. 2004. Recognition of DNA by omega protein from the broad-host range Streptococcus pyogenes plasmid pSM19035: analysis of binding to operation DNA with one to four heptad repeats. Nucleic Acids Res. 32: 3136–3147.
  • de la Hoz A.B., S. Ayora, I. Sitkiewicz, S. Fernández, R. Pankiewicz, J.C. Alonso and P. Ceglowski. 2000. Plasmid copy-number control and better-than-random segregation genes of pSM19035 share a common regulator. Proc. Natl. Acad. Sci. USA 97: 728–733.
  • del Solar G., R. Giraldo, M.J. Ruiz-Echevarría, M. Espinosa and R. Díaz-Orejas. 1998. Replication and control of circular bacterial plasmids. Microbiol. Mol. Biol. Rev. 62: 434–64.
  • del Solar G., M. Moscoso and M. Espinosa. 1993. Rolling circle-replicating plasmids from gram-positive and gram-negative bacteria: a wall falls. Mol. Microbiol. 8: 789–796.
  • Derome A., C. Hoischen, M. Bussiek, R. Grady, M. Adamczyk, B. Kedzierska, S. Diekmann, D. Barilla and F. Hayes. 2008. Centromere anatomy in the multidrug-resistant pathogen Enterococcus faecium. Proc. Natl. Acad. Sci. USA 105: 2151–2156.
  • Dmowski M. and G. Jagura-Burdzy. 2011. Mapping of the interactions between partition proteins Delta and Omega of plasmid pSM19035 from Streptococcus pyogenes. Microbiology-SGM 157: 1009–1020.
  • Dmowski M. and G. Jagura-Burdzy. 2013. Active stable maintenance functions in low copy-number plasmids of Gram-positive bacteria. II. Post-segregational killing systems. Pol. J. Microbiol. 62: 17–22.
  • Dmowski M., I. Sitkiewicz and P. Ceglowski. 2006. Characterization of a novel partition system encoded by the delta and omega genes from the streptococcal plasmid pSM19035. J. Bacteriol. 188: 4362–4372.
  • Dorokhov B., N. Ravin and D. Lane. 2010. On the role of centromere dispersion in stability of linear bacterial plasmids. Plasmid 64: 51–59.
  • Espinosa M., Cohen S., Couturier M., del Solar G., Diaz-Orjas R., Giraldo R., Janniere L., Miller C., Osborn M. and Thomas CM. 2002. Plasmid Replication and Copy Number Control in The Horizontal Gene Pool, Bacterial Plasmids and Gene Spread, edited by Thomas CM. Harwood academic publishers.
  • Evtushenko L.I., L.V. Dorofeeva, S.A. Subbotin, J.R. Cole and J.M. Tiedje. 2000. Leifsonia poae gen. nov., sp. nov., isolated from nematode galls on Poa annua, and reclassification of ‘Corynebacterium aquaticum’ Leifson 1962 as Leifsonia aquatica (ex Leifson 1962) gen. nov., nom. rev., comb. nov. and Clavibacter xyli Davis et al. 1984 with two subspecies as Leifsonia xyli (Davis et al. 1984) gen. nov., comb. nov. Int. J. Syst. Evol. Microbiol. 50: 371–380.
  • Firth N., S. Apisiridej, T. Berg, B.A. O’Rourke, S. Curnock, K.G. Dyke and R.A. Skurray. 2000. Replication of staphylococcal multiresistance plasmids. J. Bacteriol. 182: 2170–2178.
  • Fothergill T.J., D. Barillà and F. Hayes. 2005. Protein diversity confers specificity in plasmid segregation. J. Bacteriol. 187: 2651–2661.
  • Francia M.V., S. Fujimoto, P. Tille, K.E. Weaver and D.B. Clewell. 2004. Replication of Enterococcus faecalis pheromone-responding plasmid pAD1: Location of the minimal replicon and oriV site and RepA involvement in initiation of replication. J. Bacteriol. 186: 5003–5016.
  • Francia M.V., K.E. Weaver, P. Goicoechea, P. Tille and D.B. Clewell. 2007. Characterization of an active partition system for the Enterococcus faecalis pheromone-responding plasmid pAD1. J. Bacteriol. 189: 8546–8555.
  • Friedman S.A. and S.J. Austin. 1988. The P1 plasmid-partition system synthesizes two essential proteins from an autoregulated operon. Plasmid 19: 103–112.
  • Gerdes K., M. Howard and F. Szardenings. 2010. Pushing and pulling in prokaryotic DNA Segregation. Cell 141: 927–942.
  • Gerdes K., J. Møller-Jensen and R. Bugge Jensen. 2000. Plasmid and chromosome partitioning: surprises from phylogeny. Mol. Microbiol. 37: 455–66.
  • Gerdes K., J. Møller-Jensen, G. Ebersbach, T. Kruse and K. Nordström. 2004. Bacterial mitotic machineries. Cell. 116:359–66.
  • Guidi-Rontani C., Y. Pereira, S. Ruffie, J.C. Sirard, M. Weber-Levy and M. Mock. 1999. Identification and characterization of a germination operon on the virulence plasmid pXOI of Bacillus anthracis. Mol. Microbiol. 33: 407–414.
  • Guynet C., A. Cuevas, G. Moncalian and F. de la Cruz. 2011. The stb operon balances the requirements for vegetative stability and conjugative transfer of plasmid R388. Plos Genetics 7.
  • Hayes F. and D. Barillà. 2006. The bacterial segrosome: a dynamic nucleoprotein machine for DNA trafficking and segregation. Nat. Rev. Microbiol. 4: 133–143.
  • Heath D.G., F.Y. An, K.E. Weaver and D.B. Clewell. 1995. Phase variation of Enterococcus faecalis pAD1 conjugation functions relates to changes in iteron sequence region. J. Bacteriol. 177: 5453–5459.
  • Hedberg P.J., B.A.B. Leonard, R.E. Ruhfel and G.M. Dunny. 1996. Identification and characterization of the genes of Enterococcus faecalis plasmid pCF10 involved in replication and in negative control of pheromone-inducible conjugation. Plasmid 35: 46–57.
  • Howard M. and K. Gerdes. 2010. What is the mechanism of ParA-mediated DNA movement? Mol. Microbiol. 78: 9–12.
  • Huang J., S. Guo, J. Mahillon, G.A. Van der Auwera, L. Wang, D. Han, Z. Yu and M. Sun. 2006. Molecular characterization of a DNA fragment harboring the replicon of pBMB165 from Bacillus thuringiensis subsp. tenebrionis. BMC Genomics 7: 270.
  • Huang L., P. Yin, X. Zhu, Y. Zhang and K. Ye. 2011. Crystal structure and centromere binding of the plasmid segregation protein ParB from pCXC100. Nucleic Acids Res. 39: 2954–2968.
  • Jensen, R. B., and K. Gerdes. 1997. Partitioning of plasmid R1. The ParM protein exhibits ATPase activity and interacts with the centromere-like ParR-ParC complex. J Mol Biol. 269:505–513.
  • Jensen L.B., L. Garcia-Migura, A.J.S. Valenzuela, M. Lohr, H. Hasman and F.M. Aarestrup. 2010a. A classification system for plasmids from enterococci and other Gram-positive bacteria. J. Microbiol. Meth. 80: 25–43.
  • Jensen S.O., S. Apisiridej, S.M. Kwong, Y.H. Yang, R.A. Skurray and N. Firth. 2010b. Analysis of the prototypical Staphylococcus aureus multiresistance plasmid pSK1. Plasmid 64: 135–142.
  • Kearney K., G.F. Fitzgerald and J.F. Seegers. 2000. Identification and characterization of an active plasmid partition mechanism for the novel Lactococcus lactis plasmid pCI2000. J. Bacteriol. 182: 30–37.
  • Kleanthous H., C.L. Clayton and S. Tabaqchali. 1991. Characterization of a plasmid from Helicobacter pylori encoding a replication protein common to plasmids in gram-positive bacteria. Mol. Microbiol. 5: 2377–2389.
  • Kostelidou K., A.C. Jones and C.M. Thomas. 1999. Conserved C-terminal region of global repressor KorA of broad-host-range plasmid RK2 is required for co-operativity between KorA and a second RK2 global regulator, KorB. J. Mol. Biol. 289: 211–221.
  • Kulinska A., Y. Cao, M. Macioszek, F. Hayes and G. Jagura-Burdzy. 2011. The centromere site of the segregation cassette of broad-host-range plasmid RA3 is located at the border of the maintenance and conjugative transfer modules. Appl. Environ. Microbiol. 77: 2414–2427.
  • Kulinska A., M. Czeredys, F. Hayes and G. Jagura-Burdzy. 2008. Genomic and functional characterization of the modular broadhost-range RA3 plasmid, the archetype of the IncU group. Appl. Environ. Microbiol. 74: 4119–4132.
  • Kwong S.M., R.A. Skurray and N. Firth. 2004. Staphylococcus aureus multiresistance plasmid pSK41: analysis of the replication region, initiator protein binding and antisense RNA regulation. Mol. Microbiol. 51: 497–509.
  • Larsen R.A., C. Cusumano, A. Fujioka, G. Lim-Fong, P. Patterson and J. Pogliano. 2007. Treadmilling of a prokaryotic tubulin-like protein, TubZ, required for plasmid stability in Bacillus thuringiensis. Genes. Dev. 21: 1340–1352.
  • Lasocki K., A.A. Bartosik, J. Mierzejewska, C.M. Thomas and G. Jagura-Burdzy. 2007. Deletion of the parA (soj) homologue in Pseudomonas aeruginosa causes ParB instability and affects growth rate, chromosome segregation, and motility. J. Bacteriol. 189: 5762–5772.
  • Le Chatelier E., S.D. Ehrlich and L. Jannière. 1993. Biochemical and genetic analysis of the unidirectional theta replication of the S. agalactiae plasmid pIP501. Plasmid. 29: 50–56.
  • Leonard T.A., P.J. Butler and J. Löwe. 2005. Bacterial chromosome segregation: structure and DNA binding of the Soj dimer-a conserved biological switch. EMBO J. 24: 270–282.
  • Li T.Y., P. Yin, Y. Zhou, Y. Zhang, Y.Y. Zhang and T.A. Chen. 2004. Characterization of the replicon of a 51-kb native plasmid from the gram-positive bacterium Leifsonia xyli subsp. cynodontis. FEMS Microbiol. Lett. 236: 33–39.
  • Llosa M., F.X. Gomis-Rüth, M. Coll and Fd. F. de la Cruz. 2002. Bacterial conjugation: a two-step mechanism for DNA transport. Mol. Microbiol. 45: 1–8.
  • Meijer W.J., A.J. de Boer, S. van Tongeren, G. Venema and S. Bron. 1995. Characterization of the replication region of the Bacillus subtilis plasmid pLS20: a novel type of replicon. Nucleic. Acids. Res. 23: 3214–3223.
  • Moller-Jensen J. and K. Gerdes. 2007. Plasmid segregation: spatial awareness at the molecular level. J. Cell. Biol. 179: 813–815.
  • Meyer R. 2009. Replication and conjugative mobilization of broad host-range IncQ plasmids. Plasmid 62: 57–70.
  • Murayama K., P. Orth, A.B. de la Hoz, J.C. Alonso and W. Saenger. 2001. Crystal structure of omega transcriptional repressor encoded by Streptococcus pyogenes plasmid pSM19035 at 1.5 A resolution. J. Mol. Biol. 314: 789–796.
  • Ni L., W. Xu, M. Kumaraswami and M.A. Schumacher. 2010. Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc. Natl. Acad. Sci. USA 107: 11763–11768.
  • Oliva M.A., A.J. Martin-Galiano, Y. Sakaguchi and J.M. Andreu. 2012. Tubulin homolog TubZ in a phage-encoded partition system. Proc. Natl. Acad. Sci. USA 109: 7711–7716.
  • Pansegrau W., E. Lanka, P.T. Barth, D.H. Figurski, D.G. Guiney, D. Haas, D.R. Helinski, H. Schwab, V.A. Stanisich and C.M. Thomas. 1994. Complete nucleotide sequence of Birmingham IncP alpha plasmids. Compilation and comparative analysis. J. Mol. Biol. 239: 623–663.
  • Polka J.K., J.M. Kollman, D.A. Agard and R.D. Mullins. 2009. The structure and assembly dynamics of plasmid actin AlfA imply a novel mechanism of DNA Ssegregation. J. Bacteriol. 191: 6219–6230.
  • Pomerantsev A.P., A. Camp and S.H. Leppla. 2009. A new minimal replicon of Bacillus anthracis plasmid pXO1. J. Bacteriol. 191: 5134–5146.
  • Popp D., W. Xu, A. Narita, A.J. Brzoska, R.A. Skurray, N. Firth, U. Goshdastider, Y. Maeda, R.C. Robinson and M.A. Schumacher. 2010. Structure and filament dynamics of the pSK41 actin-like ParM protein implications for plasmid DNA segregation. J. Biol. Chem. 285: 10130–10140.
  • Pratto F., A. Cicek, W.A. Weihofen, R. Lurz, W. Saenger and J.C. Alonso. 2008. Streptococcus pyogenes pSM19035 requires dynamic assembly of ATP-bound ParA and ParB on parS DNA during plasmid segregation. Nucleic Acids Res. 36: 3676–3689.
  • Pratto F., Y. Suzuki, K. Takeyasu and J.C. Alonso. 2009. Single-molecule analysis of protein. DNA complexes formed during partition of newly replicated plasmid molecules in Streptococcus pyogenes. J. Biol. Chem. 284: 30298–30306.
  • Quisel J.D. and A.D. Grossman. 2000. Control of sporulation gene expression in Bacillus subtilis by the chromosome partitioning proteins Soj (ParA) and Spo0J (ParB). J. Bacteriol. 182: 3446–3451.
  • Ringgaard S., J. van Zon, M. Howard and K. Gerdes. 2009. Movement and equipositioning of plasmids by ParA filament disassembly. Proc. Natl. Acad. Sci. USA 106: 19369–19374.
  • Salje J. 2010. Plasmid segregation: how to survive as an extra piece of DNA. Crit. Rev. Biochem. Mol. Biol. 45: 296–317.
  • Salje J., P. Gayathri and J. Loewe. 2010. The ParMRC system: molecular mechanisms of plasmid segregation by actin-like filaments. Nat. Rev. Microbiol. 8: 683–692.
  • Schreiter E.R. and C.L. Drennan. 2007. Ribbon-helix-helix transcription factors: variations on a theme. Nat. Rev. Microbiol. 5: 710–720.
  • Schumacher M.A. 2012. Bacterial plasmid partition machinery: a minimalist approach to survival. Cur. Opin. Struct. Biol. 22: 72–79.
  • Schumacher M.A. 2007. Structural biology of plasmid segregation proteins. Curr. Opin. Struct. Biol. 17: 103–109.
  • Schumacher M.A., T.C. Glover, A.J. Brzoska, S.O. Jensen, T.D. Dunham, R.A. Skurray and N. Firth. 2007. Segrosome structure revealed by a complex of ParR with centromere DNA. Nature 450: 1268–1271.
  • Shih Y.L. and L. Rothfield. 2006. The bacterial cytoskeleton. Microbiol. Mol. Biol. Rev. 70: 729–754.
  • Simjee S., A.P. Fraise and M.J. Gill. 1999. Plasmid heterogeneity and identification of a Tn5281-like element in clinical isolates of high-level gentamicin-resistant Enterococcus faecium isolated in the UK. J. Antimicrob. Chemother. 43: 625–635.
  • Simpson A.E., R.A. Skurray and N. Firth. 2003. A single gene on the staphylococcal multiresistance plasmid pSK1 encodes a novel partitioning system. J. Bacteriol. 185: 2143–2152.
  • Soberon N.E., V.S. Lioy, F. Pratto, A. Volante and J.C. Alonso. 2011. Molecular anatomy of the Streptococcus pyogenes pSM19035 partition and segrosome complexes. Nucleic. Acids. Res. 39: 2624–2637.
  • Summers D.K. 1991. The kinetics of plasmid loss. Trends. Biotechnol. 9: 273–278.
  • Tanaka T. 2010. Functional analysis of the stability determinant AlfB of pBET131, a miniplasmid derivative of Bacillus subtilis (natto) plasmid pLS32. J. Bacteriol. 192: 1221–1230.
  • Tanaka T. and T. Koshikawa. 1977. Isolation and characterization of 4 types of plasmids from Bacillus subtilis (natto). J. Bacteriol. 131: 699–701.
  • Tanaka T. and M. Ogura. 1998. A novel Bacillus natto plasmid pLS32 capable of replication is Bacillus subtilis. FEBS Lett. 422: 243–246.
  • Tang M., D.K. Bideshi, H.-W. Park and B.A. Federici. 2007. Iteron-binding ORF157 and FtsZ-Like ORF156 proteins encoded by pBtoxis play a role in its replication in Bacillus thuringiensis subsp. israelensis. J. Bacteriol. 189:8053–8058.
  • Tinsley E. and S.A. Khan. 2006. A novel FtsZ-like protein is involved in replication of the anthrax toxin-encoding pXO1 plasmid in Bacillus anthracis. J. Bacteriol. 188: 2829–2835.
  • Van der Auwera G.A., J.E. Krol, H. Suzuki, B. Foster, R. Van Houdt, C.J. Brown, M. Mergeay and E.M. Top. 2009. Plasmids captured in C. metallidurans CH34: defining the PromA family of broad-host-range plasmids. Antonie Van Leeuwenhoek International Journal of General and Mol. Microbiol. 96: 193–204.
  • Vecchiarelli A.G., Y.-W. Han, X. Tan, M. Mizuuchi, R. Ghirlando, C. Biertuempfel, B.E. Funnell and K. Mizuuchi. 2010. ATP control of dynamic P1 ParA-DNA interactions: a key role for the nucleoid in plasmid partition. Mol. Microbiol. 78: 78–91.
  • Waters V. L. and D.G. Guiney. 1993. Processes at the nick region link conjugation, T-DNA transfer and rolling circle replication. Mol. Microbiol. 9: 1123–1130.
  • Weaver K.E., D.B. Clewell and F. An. 1993. Identification, characterization, and nucleotide sequence of a region of Enterococcus faecalis pheromone-responsive plasmid pAD1 capable of autonomous replication. J. Bacteriol. 175: 1900–1909.
  • Wilcks A., N. Jayaswal, D. Lereclus and L. Andrup. 1998. Characterization of plasmid pAW63, a second self-transmissible plasmid in Bacillus thuringiensis subsp. kurstaki HD73. Microbiology SGM. 144: 1263–1270.
  • Wilcks A., L. Smidt, O.A. Okstad, A.B. Kolsto, J. Mahillon and L. Andrup. 1999. Replication mechanism and sequence analysis of the replicon of pAW63, a conjugative plasmid from Bacillus thuringiensis. J. Bacteriol. 181: 3193–3200.
  • Williams D.R., D.P. Macartney and C. M. Thomas. 1998. The partitioning activity of the RK2 central control region requires only incC, korB and KorB-binding site O(B)₃ but other KorB-binding sites form destabilizing complexes in the absence of O(B)₃. Microbiology-SGM. 144: 3369–3378.
  • Yasukawa H., T. Hase, A. Sakai and Y. Masamune. 1991. Rollingcircle replication of the plasmid pKYM isolated from a Gram-negative bacterium. Proc. Natl. Acad. Sci. USA 88: 10282–10286.
  • Yin P., T.Y. Li, M.H. Xie, L. Jiang and Y. Zhang. 2006. A Type Ib ParB protein involved in plasmid partitioning in a gram-positive bacterium. J. Bacteriol. 188: 8103–8108.
  • Zielenkiewicz U. and P. Ceglowski. 2005. The toxin-antitoxin system of the streptococcal plasmid pSM19035. J. Bacteriol. 187: 6094–6105.

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