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Bacteria of the species Clostridium botulinum are sporeforming, gram-positive, anaerobic rods which are able to produce the most potent toxins in nature. Botulinum toxins are the etiologic factor of botulism in humans and animals. A lethal dose of botulinum toxin for a mouse is about 0.3 ng/kg, whilst a lethal dose for a human ranges from 0.2 µg/kg to 2 µg/kg. Historically, the differentiation of Clostridium botulinum strains is based on their ability to produce one of the seven botulinum toxins marked with letters from A to G. Nowadays, the classification based on the ability to produce botulinum toxins is not the only taxonomic criterion. C. botulinum strains are also divided into four groups which have different metabolic and culture features. Although, botulism is a rare disease, the outbreaks of botulism are difficult to control and cause economic losses in livestock. The species most susceptible to botulism are cattle and birds. The aim of this article is the characteristic of Clostridium botulinum, botulinum toxins, their action and botulism as a disease in some species of animals.
Monophasic Salmonella Typhimurium (1,4,[5],12:i:-), a worldwide emerging pathogen, has been occurring in Poland since 2008. Characterization of swine, cattle, geese, food, feed and human isolates obtained in the years 2011-2012 by pulsed field gel electrophoresis, antimicrobial resistance typing with microbroth dilution method was performed for the evaluation of their epidemiological importance for human public and animal health. The prevalence of monophasic Salmonella Typhimurium in Poland has recently increased and its proportion to classical biphasic variants reached 15.5% in 2012. The isolates revealed microbiological resistance to at least one tested compound and ten resistance profiles were found. The most frequent profile covered resistance to ampicillin, streptomycin, sulphonamides and tetracycline. Fourteen XbaI-PFGE profiles with an overall similarity of 52.4% were noted. Most of the isolates were classified to two PFGE profiles showing a 95.4% similarity. Finding of monophasic S. Typhimurium originating from people within the same XbaI-PFGE profile comprising also swine and cattle isolates indicate a possible role of animal sources in the spread of this pathogen.
Salmonella spp. is one of the most common causes of foodborne diseases. Infections are mainly caused by the consumption of food of animal origin contaminated with Salmonella. To date, over 2,610 serotypes have been recognised, but only several show epidemiological importance. The number of human cases caused by Salmonella 1,4,[5],12:i:- has increased over the last decade, and they have become one of the most frequent serovars in many countries. The paper presents current knowledge on the spread, epidemiology, antimicrobial resistance and pathogenicity of Salmonella 1,4,[5],12:i:-, also known as monophasic Salmonella Typhimurium strains. Special attention was paid to diagnostic issues related to this particular Salmonella variant.
Protozoa of the genus Cryptosporidium spp. are often an underestimated problem in livestock farms and poultry flocks. On account of difficult and time-consuming diagnostic methods cryptosporidiosis is rarely confirmed by laboratory tests. Occurring cases of persisting diarrhea are treated without a proper diagnosis. In addition, the lack of effective veterinary preparations on the market reduces treatment options. According to available literature, the estimated prevalence of Cryptosporidium spp. in cattle herds ranges from 17 to 100%. In the case of poultry flocks there is no accurate data. The paper presents the current state of knowledge about the biology, presence, methods of diagnosis, and treatments of Cryptosporidiosis.
Influenza viruses of group A, being the etiological agent of the seasonal human influenza, as well as those causing disease in birds and also viruses of swine influenza, were characterized. The present situation world wide was presented. The avian influenza lasting since 2003, caused by H5N1, was identified in 62 countries, causing all together death or culling of 220 milions of birds. The disease is classified as an avian and not a human influenza. The virus infects humans with low frequency, the transmission from human to human is not occurring or is occurring sporadically, however the mortality is 60 per cent of the diseased persons. The influenza, which is noted at present, is a disease of humans and the causing virus H1N1 is a quadruple genetic combination of avian, human and swine virus genomic segments. Until now the coarse of the disease is mild. However the number of confirmed human cases and mortality is increasing. The disease has been diagnosed in 33 countries (data from the 14th of May 2009) and WHO has declared the fifth phase of pandemic alert. Because of a high possibility of mutation and reasortation with avian and swine viruses continuous monitoring of influenza viruses in the animal reservoir is necessary which requires steady medical and veterinary cooperation.
This paper provides an overview of the current knowledge on wild boar as a reservoir of viruses, bacteria and parasites being pathogenic also to other species of animals, and for humans, but particularly to pigs belonging to the same species, Sus scrofa, as the wild boar. Since wild boar and domestic pigs belong to the same taxonomic species they are susceptible to the same pathogens and can infect each other. Therefore free – ranging wild boar are increasingly considered to be a threat to the pig industry and the international movement of pigs and swine products. Particularly African swine fever, classical swine fever, and foot and mouth disease are those OIE-listed diseases, discussed in the paper. Additionally, domestic pigs can be infected from wild boar by PPV, PCV2, TGE and ADV. The last mentioned microorganism is causing infection and disease also in other species of animals. The wild boar is participating, by carriership, of infecting several species of animals and human by Leptospira serotypes, Brucella suis, Yersinia enterocolitica, Salmonella spp., pathogenic serovars of Escherichia coli. The same relates to bovine tuberculosis, Japanase encephalitis virus and influenza A typ viruses. Finally trichinellosis transfer from wild boar to humans with not cooked meat containing larves of Trichinella spp. is mentioned. In general remarks it is noted that to prevent pathogen introduction from wild boar to domestic animals particularly to pigs, but also other species and to humans the surveillance of the wild boar behaviour in their living conditions and environment is recommended.
Clostridium perfringens is one of the most widespread anaerobic spore forming bacteria found in the environment. The toxotype A of the species inhabits the gastrointestinal tract of birds and mammals exhibiting pathogenic properties in the immunocompromised host. The virulence determinants of C. perfringens are toxins and extracellular enzymes which cause gas gangrene, enteritis necroticans, food poisoning, and non-food borne gastrointestinal infections in humans. The young animals suffer from enterotoxaemia, dysentery and necrotic enteritis due to the anaerobic spore forming bacilli. This article reviews the epidemiological significance of C. perfringens and its disease diagnostics, taking into account all known to date virulence determinants of the microorganism.
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