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Wegorczyca [Strongyloidosis]. Cz.6.Modele zwierzece

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Animal models (rat, mous, dog and monkey) being used in comparative investigations on immunobiology, pathology, clinical manifestations and treatment ot human atrongyloidosis were presented.
The formation of Strongyloides stercoralis infections in the tropical countries and in the temperate climatic zone, with special attention to the factors and the high risk groups, were described. The concurrent infections, prevention and control of strongyloidosis was also presented.
Strongyloidosis. Part VIII. Parasitological diagnosis. The effectiveness and safety of the methods of detecting Strongyloides stercoralis, by passing larvae from the faeces to water, in duodenal fluid (duodenal intubation, Enterotest), in sputum and other body fluids, have been estimated. The author recommend Baermann technique for detecting S. stercoralis in individual examinations and Dancescu technique in mass field examinations. The detection of S. stercoralis larvae by the two methods ought to be checked by Fülleborn agar Petri dish technique in order to identify parasite to the species level.
The source of invasion of Strongyloides stercoralis and the routes of transmission strongyloidosis were presented. The survival, development and behavior forms parasitic and free-living generation of S. stercoralis in soil and host was also described.
The role of specific, non-specific cellular and humoral immunity in different clinical forms of strongyloidosis is discussed. The role of immunosuppression in the immunocompromised patients with disseminated strongyloidosis is also given.
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Pathogenesis and pathology of alimentary system of man infected with Strongyloides stercoralis are shown. Allergic, macroscopic lesions of duodenal, small and large intestinal walls, existing in different clinical strongyloidosis types are discussed. The role of endoautoinfection in the course of strongyloidosis in the immunocompromised patients with fatal disseminated strongyloidosis is shown. In disseminated strongyloidosis lesions include stomach, liver and rarely pancreas. Pathogenesis of macroscopic and microscopic lesions in respiratory, circulatory and central nervous systems of a man infected with Strongyloides stercoralis, mainly in the course of fatal disseminated strongyloidosis, is shown. Rare cases of presence of parasite filariform larvae in urinary tract, reproductive system, and other organs are also given.
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Wegorczyca [Strongyloidosis] - przypadek kliniczny

84%
A case of Strongyloides stercoralis infection was described.
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Wegorczyca [strongyloidosis]. Cz.9. Leczenie

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Strongyloidosis. Part IX. Treatment. The treatment of chronic and massive (uncomplicated) and severe (complicated) disseminated srrongyloidosis, was presented from the historical point of view. The sequence of achievements in regard of treatment of the gentian violet, dithiazine iodide, benzimidazoles (thiabendazole, mebendazole, albendazole, cambendazole), ivermectin and cyclosporin A, was described. The recommendations for treatmenl of strongyloidosis are also given.
The distribution of Strongyloides stercoralis infection in human host in Africa and Europe were described.
Specific, recurrent, tortuous or linear serpiginicus urticarial rash and nonspecific, stationary urticarial skin lesions appearing during infection with Strongyloides stercoralis and concomitant clinical manifestations in human were presented. Pathognomic form of larva currens in primary infection with S. stercoralis and in already allergic host during exoautoinfection of the parasite, and similar skin lesions appearing during the endoautoinfection but without the presence of S. stercoralis larvae in skin were described. Nonspecific urticarias were set against the pathognostic lesions.
Strongyloidosis was induced by percutaneous injection of rabbits; then organ changes were tested. It has been found that Strongyloides papillosus evoked changes in intestine, liver, kidney and lung. No notable changes were found in heart, spleen and suprarenal gland. These changes may be provoked not only directly by the presence of these parasites but also by the products of metabolism of S. papillosus.
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