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Zastosowanie hydroksyapatytu w leczeniu ubytków kostnych powstałych w następstwie zmian zapalnych w obrębie szczęki i żuchwy - opis przypadków

100%

Polkowska I., Sobczynska-Rak A., Szyszkowska A., Koper J., Slosarczyk A.

Medycyna Weterynaryjna

2012

tom 68

nr 07

Hydroxyapatite in the form of granules of different sizes is a popular material used in oral surgery. It is widely used in the guided bone regeneration technique (GBR). The essence of this method is to assist the healing process of bone defects by means of implantation material, natural or synthetic, which is placed within the bone cavity. Hydroxyapatite implant reduces the volume of the hematoma forming in the wound, prevents infection and has osteoconductive properties. It also increases local bone mechanical strength in the treated area. Three cases of patients with bone cavities after surgical treatment of inflammatory lesions have been described. The cavities have been filled with hydroxyapatite granules. The material has been used in two cases in animals in the treatment of oro-nasal fistula and in one case in a human after enucleation of an inflammatory lesion. It has been proved that hydroxyapatite as an implantation material provides better and faster recovery of bone lesions, while the bone that forms on the implant has a more regular structure than bone generated only on the basis of a clot. In the described cases the treatment of bone cavities in animals and humans proved to be a hydroxyapatite biomaterial accelerating the reconstruction of bone tissue.

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Kranioplastyka u psa

100%

Rybinski P., Szewczyk M., Szalas A.

Życie Weterynaryjne

2007

tom 82

nr 11

933-935

Analiza przydatności badań mikro-CT w ocenie wyników leczenia eksperymentalnych ubytków trzonu kości udowej królika z zastosowaniem fosforanu trójwapniowego hydroksyapatytu

100%

Skwarcz S., Bryzek I., Gregosiewicz A., Warda E., Skwarcz J., Nadulski R., Starek A.

Medycyna Weterynaryjna

2016

tom 72

nr 04

This paper focuses on analysing the usefulness of micro-CT scans in assessing the efficacy of hydroxyapatite tricalcium phosphate in the treatment of experimental femoral bone defects in rabbits. The tests were conducted on 12 male Termond White rabbits, which had previously undergone bilateral surgical interventions involving femoral bone diaphysis (shaft) performed under operating-theatre conditions. The bones were drilled with a 4 mm drill. All rabbits had their left femur defects left without filling, whereas the right femur defects were filled with 100 mg of hydroxyapatite tricalcium phosphate preparation. After 8 weeks, the animals were euthanized to take specimens of both femurs. Micro-CT scans were taken with a Skyscan 1174 (Bruker – SkyScan). The area examined was subjected to volume rendering to determine the following parameters: Vb [mm³] – total volume of the specimen, Vb₁ [mm³] – high-density fraction volume in the specimen, and Vb₂ [mm³] – low-density fraction volume in the specimen, calculated by the formula Vb₂ [mm³] = Vb – Vb₁. Subsequently, after appropriate preparation, the specimens were assessed histopathologically. The analysis of micro-CT scan results showed a statistically significant increase in the total volume (Vb) of the part of the femur filled with the bone substitute (B) compared to the control group (A), and an increase in the low-density fraction volume (Vb₂). The volume of high-density fraction tissue (Vb₁) showed no statistically significant difference between the groups. The histopathological assessment of the control-group specimens (A) showed that bone defects had been completely filled by osteoid tissue with an irregular, feathery structure, and the cortical layer exhibited a marrow-induced thickening. The specimens from group (B) showed amorphous masses of the bone-substitute preparation surrounded by callus formed concentrically around preparation particles.

Ograniczanie wyników

2 Medycyna Weterynaryjna

1 Życie Weterynaryjne

1 Bryzek I.

1 Gregosiewicz A.

1 Koper J.

1 Nadulski R.

1 Polkowska I.

1 Rybinski P.

1 Skwarcz J.

1 Skwarcz S.

1 Slosarczyk A.

1 Sobczynska-Rak A.

1 Starek A.

1 Szalas A.

1 Szewczyk M.

1 Szyszkowska A.

1 Warda E.

1 2016

1 2012

1 2007

Wyniki wyszukiwania

Zastosowanie hydroksyapatytu w leczeniu ubytków kostnych powstałych w następstwie zmian zapalnych w obrębie szczęki i żuchwy - opis przypadków

Kranioplastyka u psa

Analiza przydatności badań mikro-CT w ocenie wyników leczenia eksperymentalnych ubytków trzonu kości udowej królika z zastosowaniem fosforanu trójwapniowego hydroksyapatytu