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Toxicity of bisphenol a on humans: a review

100%

Preethi S., Sandhya K., Lebonah D. E., Prasad C. V., Sreedevi B., Chandrasekhar K., Kumari J. P.

International Letters of Natural Sciences

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2014

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tom 22

Bisphenol A (BPA) is a plastic ingredient produced in large quantities for use primarily in the production of polycarbonate plastics and epoxy resins. The present review focused on different mechanisms of BPA on human health in enzymatic, androgenic, neurological, liver and reproductive systems. The review explained the influence of BPA on different stages of human life likely in foetal stage, children and adults stages. The review also concentrated on how to handle BPA, treatment, preventive measures against BPA exposure.

2

Toxicity of Fusarium species in section Gibbosum

100%

Wing N., Burgess L. W., Bryden W. L., Lauren D. R.

Hodowla Roślin, Aklimatyzacja i Nasiennictwo

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1993

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tom 37

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nr 1-2

3

Hygienic assessment of glauconite using for neutralization of substandard drugs

88%

Khopyak N., Manenko A., Tkachenko H., Kurhaluk N.

Słupskie Prace Biologiczne

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2014

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nr 11

4

Polybrominated diphenyl ethers in the environment, their source, toxicity and levels

88%

Czerwinski J.

Journal of Elementology

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2009

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tom 14

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nr 3 Suppl.

23

5

Dichlorvos toxicity on fish - a review

88%

Deka S., Mahanta R.

European Journal of Biological Research

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2015

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tom 05

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nr 3

6

Interactions of mercury in the environment

88%

Maluszynska I., Popenda A., Maluszynski M. J.

Annals of Warsaw University of Life Sciences - SGGW. Land Reclamation

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2013

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tom 45

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nr 2

Mercury is a pollutant of global concern largely due to its potential for biological transformation into harmful forms and bioaccumulation through the food chains. Mercury is not able to biodegrade in the environment and it forms many toxic inorganic and organic complexes. The strongest harmful effects of mercury concerns the central nervous system. The harmful effects of mercury is very stable, because the mercury compounds bind to enzymes. Getting into the brain, mercury displace zinc from brain tissue, and thus reduces the effi ciency of the brain. Then excreted in the cell nuclei and destroys the genetic material. The antagonism between zinc and mercury partially modifies its toxic effects. Mercury is combined with active groups of proteins and amino acids, accumulating in the body. Selenium has similar affinity, limiting connects these groups with mercury, reducing its toxicity. Antagonists are also cadmium, mercury and zinc, but their effects are most likely related with the action of selenium. Antagonist for mercury is also iodine content in the thyroid gland which is lowered, the excessive concentration of mercury in the body. It is known that taking selenium, zinc and thiols, e.g. GSH and NAC, are of prime importance in considering effects on human organisms as well as the level of its excretion. Due to the fact that interactions are dynamic and poorly understood at present the better understanding of their role requires the further studies. Despite that have been identifi ed interactions between elements and mercury, limiting its toxic effects, we still do not have sufficient knowledge about how to reduce the negative effects of this element on the human body. The definition of what is an acceptable daily dose of mercury for humans also does not quarantee protection of the health, because we do not know the exact limits of tolerance for different follow-up effects of prolonged exposure to low concentrations. It should also be pointed out that the interactions are dynamic and weakly understood at present. The better understanding of the role the afore-mentioned particles may be crucial in the to study the interaction between mercury and various environmental components and to find a substance that interacts with mercury to reduce its toxicity to living organisms.

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Evaluation of the combined effect of phenol derivatives in two-component mixtures

88%

Boruszak-Sobolewska D., Orlowski J.

Acta Poloniae Toxicologica

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1996

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tom 04

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nr 1

8

Effect of cadmium speciation on 109Cd uptake and toxicity to Staphylococcus aureus

88%

Malm A., Tynecka Z., Zajac J.

Polish Journal of Environmental Studies

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1998

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tom 07

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nr 3

Cadmium is an environmental pollulant highly toxic to all forms of life. In this paper we studied by polarography the effect of the environment on cadmium speciation and also the effect of this speciation on 109Cd uptake and toxicity to living cells of cadmium-sensitive Staphylococcus aureus 17810S in different media. It was found that the magnitude of passive ,09Cd adsorption was proportional to the content of free Cd2+ in the medium (cadmium speciation). In contrast, the magnitude of energy-requiring l09Cd accumulation did not depend on cadmium speciation and was similar in all media. This could be due to the higher affinity of Cd2+ to the Mn2+ transport system than to the complexing ligands in the medium. Thus, cadmium uptake by S. aureus 17810S depends both on environmental and cellular factors and under all circumstances results in strong toxicity to living cells.

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Toxicity of industrial wastewater treated by Fenton's reagent

88%

Barbusinski K.

Polish Journal of Environmental Studies

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2005

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tom 14

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nr 1

Toxicity of four types of industrial wastewater, treated by Fenton’s reagent, was analyzed. Toxicity was measured using bioluminescent bacteria Vibrio fischeri NRRL B-11177. Application of Fenton’s reagent was a efficient method for treatment of this wastewater. Nevertheless, high efficiency of organic components degradation was not always followed by reduction of toxicity to a very low level. In all cases, in order to achieve total reduction of toxicity, it was necessary to increase both the H2 O2 dose and reaction time. It was concluded that optimization of Fenton’s reaction should be performed assuming toxicity changes in the examined wastewater. Reduction in toxicity should be a critical measure of the success of this method. Such an approach should be general practice in relation to all hazardous industrial wastewater.

10

Use of Fenton's reagent for removal of pesticides from industrial wastewater

88%

Barbusinski K., Filipek K.

Polish Journal of Environmental Studies

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2001

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tom 10

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nr 4

The process of pesticide (gamma -HCH and inactive isomers alpha- and beta -HCH, DDT, DMDT, fenitrothion and chlorfenvinphos) removal from industrial wastewater using Fenton's reaction has been analysed. Most of the pesticides were completely degraded at H2O2 Concentration of 2.5 g/dm(3); however, only at 5 g/dm(3) were all the examined pesticides completely removed and the results repeatable. The most effective process was for fenitrothion (from 98.5 to 100%) and chlorfenvinphos (from 97.1 to 100%), whereas organochlorine pesticides were removed with efficiency of more than 90%. The optimum ratio of [Fe2+] to [H2O2] was from 1:3 to 1:2 while the optimum pH was from 3.0 to 3.5. Tests based upon a bioluminescent bacteria Vibrio fischeri NRRL B-11177, at optimized Fenton's reaction parameters, show the reduction of toxicity to non-toxic levels.

11

Tolerance of antacids

88%

Sewing K. F.

Journal of Physiology and Pharmacology. Supplement

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1993

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tom 44

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nr 1

12

A study of the toxic effects of six dibenzofuranes in mitochondria from rat liver

88%

Manente S., Iero A., Fabris R., Perin G., Rizzoli V., Bragadin M.

Polish Journal of Environmental Studies

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1999

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tom 08

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nr 3

13

Computation of the partition coefficient of anionic and amphotheric surfactants between n-octanol and water

75%

Zielinski R.

Towaroznawcze Problemy Jakości. Polskie Towarzystwo Towaroznawcze

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2017

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nr 2

14

Toxicity of salinomycin and narasin in turkeys

75%

Markiewicz W., Barski D., Burmanczuk A., Tomaszewska E.

Journal of Elementology

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2014

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tom 19

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nr 3

Coccidiosis continues to be one of the most serious diseases in poultry breeding, causing major economic losses in this industry. Many trials are conducted to prevent and control this disease. However, only a few medications are approved for use in the prevention and treatment of coccidiosis. Ionophore coccidiostats (e.g. salinomycin and narasin) act by altering the transmembrane movement of monovalent or divalent ions (Na+, K+, Ca2+, Mg2+, Rb+, Cs+), resulting in altered ionic gradients and disturbed physiological processes in coccidia. In broiler and turkey breeding, these agents are used for nearly the whole fattening period. Ionophore coccidiostats have a narrow safety margin. Their toxicity is probably due to a disturbed ion balance or to oxidative damage. Although ionophore coccidiostats are considered to be relatively safe for target animals, there are numerous reports of poisoning cases caused by these medications in birds. This paper summarizes the current state of knowledge on the toxicity of salinomycin and narasin in turkeys. It reviews the data concerning the symptoms, mortality rate and possible causes of poisoning with these agents. Moreover, the paper discusses the legal regulations regarding the use of these drugs in poultry.

15

Content of pyrrolizidine alkaloids in the leaves of coltsfoot (Tussilago farfara L.) in Poland

75%

Adamczak A., Opala B., Gryszczynska A., Buchwald W.

Acta Societatis Botanicorum Poloniae

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2013

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tom 82

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nr 4

Coltsfoot (Tussilago farfara L.) is a common species, widely used in European and Chinese traditional medicine for the treatment of respiratory diseases. However, raw material from this plant contains hepatotoxic pyrrolizidine alkaloids (PAs). The aim of the study was to determine the variability of the level of PAs (senkirkine and senecionine) in leaves of coltsfoot originated from natural populations in Poland. In the phytochemical analysis, 20 samples of T. farfara were used. This plant material was obtained from the Garden of Medicinal Plants in Plewiska near Poznań and originated from different regions of Poland. Coltsfoot leaves were harvested in the middle of July of 2010 and then dried at room temperature. The alkaloid content was detected using the HPLC-DAD method. The amount of PAs in leaves of T. farfara changed in a wide range from 0.06 to 1.04 μg g−1 of dry matter (DM). The content of senkirkine and senecionine was positively correlated (r = 0.68, P = 0.001). There was no statistically significant correlation between the amount of PAs as well as leaf weight and water content in leaves of T. farfara. Our results showed that a medium-sized leaf of coltsfoot (0.33 g DM) may contain from 0.02 to 0.34 μg of PAs (on average 0.14 μg). The level of PAs was not associated with the region of Poland, but phytochemical similarity of samples was usually visible at the local scale. Coltsfoot leaves are characterized by a high variability of the content of toxic PAs, much higher than in the case of the main active compounds, especially flavonoids and mucilage. This phytochemical variability is mainly genetically determined (samples came from a garden collection), and it can be increased by environmental factors. Our investigations indicate that Polish natural populations of T. farfara may provide raw material with a low level of toxic PAs.

16

The role of hydrogen sulfide in pathologies of the vital organs and its clinical application

75%

Jin Z., Chan H., Ning J., Lu K., Ma D.

Journal of Physiology and Pharmacology

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2015

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tom 66

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nr 2

17

L-cysteine ameliorated testicular toxicity induced by acrylamide in rats

75%

Hossam El-Din M.Omar H. E.-D. M., Abd-elghafar S. K., Fiedan I. O., Ahmed E. A.

European Journal of Biological Research

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2015

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tom 05

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nr 2

18

Application of characteristic volumes and topological indices of molecules in toxicity prediction of several anionic surfactants in aquatic environment

75%

Zielinski R.

Towaroznawcze Problemy Jakości. Polskie Towarzystwo Towaroznawcze

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2018

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nr 2

19

Input of mercury compounds with the Vistula waters

75%

Brzezinska A., Bogacka T., Taylor R., Trzosinska A.

Oceanologia

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1979

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tom 11

20

Interaction of hierarchical nanoporous carbons (HNCs) with chicken embryo red blood cells (RBC)

75%

Bugajska Z., Jaworski S., Daniluk K., Biniecka P., Sosnowska M.

Annals of Warsaw University of Life Sciences - SGGW. Animal Science

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2017

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tom 56[1]

Interaction of hierarchical nanoporous carbons(HNCs) with chicken embryo red blood cells (RBC.The purpose of this study was to characterize toxicity of hierarchical nanoporous carbons (HNCs) on chicken embryo red blood cells (RBC). RBC are a perfect model to adapt the hemolysis assay in evaluation of the in vitro blood compatibility of nanoparticles. The samples of blood were treated with different concentration of HNCs (10 µg/ml, 50 µg/ml and 100 µg/ml). Hemolysis assay showed that the hemolytic activity depends on the dose of HNCs. The microscope observations have shown a difference in morphology between treated and untreated RBC: changes in cell membrane shape and the occurrence of pathological erythrocytes forms.

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