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Today, surgical dissection and tissue coagulation with both monopolar and bipolar coagulation as well as LigaSure high frequency current generator (HFCG) are the surgical modalities of choice in the treatment of thyroid pathology. However, the question of the high frequency current effect on the morphofunctional condition of the posthemithyroidectomic parenchyma is still disputable. The goal of the research is a thorough histological analysis of the surgically removed thyroid tissue specimen. The nodular goitre of 50 patients was subject to the histological study. The surgery was performed with the LigaSure HFCG. The 1.0x0.5 thyroid tissue specimens were excised from three areas. Hemithyroidectomy lasted for 40-50 min and thyroidectomy – 120 ± 4.2 min. In both procedures, the blood loss was within 70-150 ml, no haemorrhage being observed in both intra-and postoperative period. The zonal effect of high frequency current on the thyroid structure was determined morphologically, namely coagulation necrosis in the site of direct action, intensified secretory response of the thyroid tissue to the extremal factor in the perifocal area, and typical structure of the nodular goitre with the signs of impaired microcirculation in the remote area. Morphologic changes of the thyroid gland, with high frequency current used as a dissector, are distance-dependent.
The size and shape of the thyroid gland is subject to much variation, as stated by Wood Jones. Literature is replete with a large number of variations of the gland. By utilizing various techniques like gross dissection, histology, developmental anatomy, and recently thyroid scans and scintigraphy, some common and certain rare anomalies of the thyroid with their possible developmental bases are described in the literature. An attempt has been made to study the thyroid glands in 90 male cadavers available in our department, with ages ranging from 60 to 75 years with mean height of 5’4”. The parameters that were observed included the length and width of lobes, presence or absence of pyramidal lobe, levator glandulae thyroideae, and isthmus with its relation to the tracheal rings. The average length of the right lobe was 4.32 cm, and the left lobe was 4.22 cm. The thickness of the right lobe was 1.13 cm, and the left lobe was 1.18 cm. Pyramidal lobe was present in 34 (37.77%) cases, frequently arising from the left lobe, while the levator glandulae thyroideae was present in 27 (30%) instances, mostly attached superiorly to the body of the hyoid bone. The isthmus was absent in 15 (16.66%) cases; its relation with the tracheal rings greatly varied from the cricoid cartilage to the fourth tracheal ring. Knowledge of variations of the thyroid assumes significance as this has relevance in the resection of thyroid, tumours, and tracheostomy. (Folia Morphol 2010; 69, 1: 47–50)
The morphology and distribution of the cholinergic and adrenergic nerve fibres were described in the thyroid gland of the domestic hen. The adrenergic structures were visualised with glyoxylic acid and with immunohistochemical staining for tyrosine hydroxylase (TH), the marker for adrenergic nerve structures. Cholinergic structures were visualised using the Karnovsky and Roots method. It was found that the thyroid gland is supplied with numerous adrenergic and cholinergic nerve fibres, which occur as small or large bundles or single nerve fibres. These were located around blood vessels, under the fibrous capsule and in the vicinity of secretory vesicles.
The thyroids of 85 European bison, Bison bonasus (Linnaeus, 1758) collected from the selectively shot animals (43 males and 42 females) in the years 1982 - 1984 in the Białowieża and Borecka Forests, were examined. The animals were shot in winter at low temperatures: (Dec., and Jan. - March) as well as summer (June - Sept.). Their age ranged from 1 month to 25 years. The thyroid of calves shoved small differentiation in histological structure. Size of the follicles as well variability of their shape increases significantly in older animals, and large follicles are present in relatively great number in the very old bison. Characteristic histological signs of higher activity of the thyroid can be noticed in warm summer months as compared with low temperature winter months.
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