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1

Interleukin 3-dependent, asialo-GM1-positive cell line with natural cytotoxic but without natural killer cytotoxic activity

100%
Strzadala L., Ziolo E., Matuszyk J.
Archivum Immunologiae et Therapiae Experimentalis
|
1994
|
tom 42
|
nr 3
2

The graft-versus-host [GvH] reaction and experimental trichinellosis. III. Induction of angiogenesis by spleen cells from mice infected with Trichinella spiralis

100%
Bany J., Marczak M.
Acta Parasitologica
|
1992
|
tom 37
|
nr 4
Lymphocyte-induced angiogenesis (LIA), a vascular response was observed when allogenic immunocompetent lymphocytes of C3H/w mice infected with Trichinella spiralis were inoculated intradermally into irradiated BALB/c. It was shown that intestinal phase of T. spiralis infection stimulated mainly CD5 T cells dependent angiogenesis. The enhancement of angiogenesis did not occur in the early and late muscular phases of the infection. It is suggested, that changes in the intensity of angiogenesis may play a role in spreading of new-born larvae in the host.
3

Lymph node basophiles and mast cells in the local graft-versus-host reaction in mice

100%
Wlodarski K. H., Skarpetowski A., Kowalski M., Wlodarski P. K.
Archivum Immunologiae et Therapiae Experimentalis
|
1992
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tom 40
|
nr 5-6
4

Chrysotile A affects YAC-1 cytolytic activity of spleen cells

84%
Moniewska A., Szyba K., Jazwiec B., Lange A.
Archivum Immunologiae et Therapiae Experimentalis
|
1989
|
tom 37
|
nr 1-2
5

Was the serine protease cathepsin G discovered by S. G. Hedin in 1903 in bovine spleen?

84%
Palesch D., Sienczyk M., Oleksyszyn J., Reich M., Wieczerzak E., Boehm B., Burster T.
Acta Biochimica Polonica
|
2011
|
tom 58
|
nr 1
 In the beginning of the 20th century, enzymes with proteolytic activity were classified as peptidases, Erepsin, and proteases. Among these, pepsin, trypsin, and autolytic enzymes were of the protease class. Spleen-derived proteases were poorly characterized until Sven Gustaf Hedin performed several digestion experiments with bovine spleen. He incubated minced bovine spleen under acidic or neutral conditions and characterized two active proteases; the results were published in 1903. The first protease was named α-protease and was active under neutral conditions. The second was named β-protease and was active under acidic conditions. We replicated Hedin's experiments according to his methods and found, by using activity-based probes to visualize proteases, that the historical α-protease is the present-day serine protease cathepsin G (CatG), which is known to be important in several immune processes, including antigen processing, chemotaxis, and activation of surface receptors. The β-protease, however, comprised different proteases including CatX, B, S, and D. We suggest that Hedin described CatG activity in bovine spleen over 100 years ago.
6

Age related decline in functional T cell subsets inthe mouse

84%
Boersma W. J. A., Vissinga C. S.
Folia Histochemica et Cytobiologica
|
1986
|
tom 24
|
nr 1
7

Investigation of influence of Proteus mirabilis LPS polysaccharide part on the murine immune cells activation

84%
Klink M., Sonn C. H., Kaca W., Kim Y. S.
Archivum Immunologiae et Therapiae Experimentalis
|
1999
|
tom 47
|
nr 3
8

Oral treatment of rats with bovine lactoferrin inhibits carrageenan-induced inflammation; correlation with decreased cytokine production

84%
Zimecki M., Miedzybrodzki R., Szymaniec S.
Archivum Immunologiae et Therapiae Experimentalis
|
1998
|
tom 46
|
nr 6
9

Cytotoxic T lymphocyte response to herpes simplex virus type 1 is composed of both CD8plus and CD4plus T cell phenotypes in acute and memory states

84%
Niemialtowski M. G., Rouse B. T.
Archivum Immunologiae et Therapiae Experimentalis
|
1994
|
tom 42
|
nr 4
10

Generation of anti-hapten T cell cytotoxicity in vivo. Relationship to contact sensitivity and the role of contrasuppression

84%
Ptak W., Friedman A. M., Flood P. M.
Archivum Immunologiae et Therapiae Experimentalis
|
1994
|
tom 42
|
nr 3
11

Differences in stimulation of CD45plus cells from mouse spleen population enriched in dendritic cells depending on the virulence of herpes simplex virus type 1 strains

67%
Rechnio M., Siennicka J., Gut W., Litwinska B.
Polish Journal of Microbiology
|
2004
|
tom 53
|
nr 3
The interaction of CD28 with one of the B7 molecules (CD80 and CD86) on professional antigen-presenting cells (APC) is generally considered to be the most important co-stimulatory signal for T cell activation. Several lines of evidence suggest that dendritic cells (DC), the most potent antigen presenting cells known, play a role in the immunological control of herpes simplex virus (HSV) infections. The fact that CD86 is strongly up-regulated together with other co-stimulatory molecules during DC maturation suggests that it plays an important role in induction of immune response. To determine the effect of virulence on up-regulation of CD86, we stimulated population of spleen cells enriched in dendritic cells by HSV-1 strains characterised by different pathogenicity. We analysed cells, which express CD45 molecule. HSV-1 ts, earlier described as less virulent for mice, stimulated an increased expression of co-stimulatory molecule CD86 than wild strain did.
12

Influence of acute and chronic ethanol treatment on interferon production in mice

67%
Daniluk J., Kandefer-Szerszen M.
Archivum Immunologiae et Therapiae Experimentalis
|
1994
|
tom 42
|
nr 3
13

Influence of recipient pretreatment with donor spleen cells and 15-deoxyspergualin on rat skin graft survival

67%
Krzymanski M., Oko A., Waaga A. M., Pawliczak E., Wiktorowicz K.
Archivum Immunologiae et Therapiae Experimentalis
|
1997
|
tom 45
|
nr 5-6
14

Immunotropic activities of benzisoselenazolones and organic diselenides in mice

59%
Blaszczyk B., Inglot A. D., Kowalczyk-Bronisz S. H., Szymaniec S., Mlochowski J.
Archivum Immunologiae et Therapiae Experimentalis
|
1995
|
tom 43
|
nr 5-6
15

Influence of 4-hydroxynonenal and spleen cells on primary hepatocyte culture and a novel liver-derived cell line resembling hepatocyte stem cells

51%
Cipak A., Borovic S., Jaganjac M., Bresgen N., Kirac I., Grbesa I., Mrakovcic L., Cindric M., Scukanec-Spoljar M., Gall-Troselj K., Coric M., Eckl P., Zarkovic N.
Acta Biochimica Polonica
|
2010
|
tom 57
|
nr 2
 Liver is a unique mammalian organ with a great capacity of regeneration related to its function. After surgical resection or injury, hepatic cells, especially hepatocytes, can proliferate rapidly to repair the damage and to regenerate the structure without affecting the function of the liver. Loss of catalase activity during regeneration indicates that oxidative stress is present in the liver not only in pathological conditions but also as a "physiological" factor during regeneration. As we have shown in our previous work, liver stem cell-like cells treated with 4-hydroxynonenal (HNE), a cytotoxic and growth regulating lipid peroxidation product, recover in the presence of spleen cells. In the current study we characterized this novel cell line as liver-derived progenitor/oval-like cells, (LDP/OCs), i.e. functional liver stem-like cells. We showed that LDP/OC were OV6 positive, with abundant glycogen content in the cytoplasm and expressed α-fetoprotein, albumin, biliverdin reductase and γ-glutamyl transferase. Also, we compared their growth in vitro with the growth of cultured primary hepatocytes stressed with HNE and co-cultured with autologous spleen cells. The influence of spleen cells on HNE-treated primary hepatocytes and on LDP/OCs showed that spleen cells support in a similar manner the recovery of both types of liver cells indicating their important role in regeneration. Hence, LDP/OC cells may provide a valuable tool to study cell interactions and the role on HNE in liver regeneration.
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