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High level expression of STAG1-PMEPA1 in an androgen-independent prostate cancer PC3 subclone

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Hirokawa Y. S., Takagi A., Uchida K., Kozuka Y., Yoneda M., Watanabe M., Shiraishi T.

Cellular and Molecular Biology Letters

2007

tom 12

nr 3

In this paper, we describe the isolation and characterization of two PC3 subclones. One subclone, mr, showed an epithelial phenotype, the other, M1, showed a sarcomatous morphology. Transplanted into nude mice, mr developed tumors at a dramatically faster rate than M1. Comparing the two subclones, differentially expressed genes were identified, including E-cadherin, IL-8 and STAG1/PMEPA1. These genes were expressed at higher levels in mr than in M1.

Ograniczanie wyników

1 Cellular and Molecular Biology Letters

1 Hirokawa Y. S.

1 Kozuka Y.

1 Shiraishi T.

1 Takagi A.

1 Uchida K.

1 Watanabe M.

1 Yoneda M.

1 2007

Wyniki wyszukiwania

High level expression of STAG1-PMEPA1 in an androgen-independent prostate cancer PC3 subclone