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Factors leading to dermatophytosis

100%

Herizchi Qadim H., Golforoushan F., Azimi H., Goldust M.

Annals of Parasitology

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2013

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tom 59

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nr 2

Tinea or dermatophytoses are of skin superficial and fungous infections affecting keratinized tissues such as hair, nail, and superficial layer of epidermis. This study aimed at evaluating some predisposing factors for tinea corporis, because elimination or treatment of them not only ceases spreading of the lesion but also prevents reinfection. In this descriptive cross- sectional study patients who were visited in Sina Hospital in Tabriz and had confirmed tinea corporis with direct ungal smear were selected. Other regarding were age, sex, occupation and predisposing factors. Of 76 confirmed cases, 46(60.5%) were males and 30(30.5%) were females. Tinea corporis was common in the third decade. The main predisposing factor was dry skin. Diabetes was found only in 4(5.2%) patients. According to the results of the present research, xerosis was the most common factor leading to tinea corporis in these patients rather than diabetes or lymphoma that it’s diagnosis, treatment and some simple educations may inhence improvement of tinea corporis and prevents other superficial infections too.

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NK and NKT-like cells in patients with recurrent furunculosis

100%

Nowicka D., Grywalska E., Fitas E., Mielnik M., Rolinski J.

Archivum Immunologiae et Therapiae Experimentalis

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2018

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tom 66

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nr 4

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Staphylococcus pseudintermedius, both commensal and pathogen

80%

Chrobak-Chmiel D., Golke A., Dembele K., Cwiek K., Kizerwetter-Swida M., Rzewuska M., Binek M.

Medycyna Weterynaryjna

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2018

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tom 74

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nr 06

Staphylococcus pseudintermedius is considered to be a both commensal and opportunistic canine pathogen. The anal, perineal and nasal locations appear to be the main S. pseudintermedius colonization sites, from which bacteria are transmitted to other body sites, causing secondary infections. When the immune system is compromised because of an underlying condition, the skin becomes susceptible to infection. Thus, the host’s condition seems to play a crucial role in the pathogenesis of S. pseudintermedius infections. There are some predisposing factors, one of which is atopic dermatitis. The pathogenic effects of S. pseudintermedius are mediated by several virulence factors, for instance superantigens, which play an important role by causing dermatitis. The immune system has evolved many different mechanisms to recognize and deal with pathogens, but bacteria have also developed various strategies to evade them. In this review, we focus on early stages of the innate immune response with particular emphasis on the mechanisms of recognition of staphylococci and the action of antimicrobial peptides.

4

Trichophyton mentagrophytes-associated Majocchi’s granuloma treated with cryotherapy

80%

Pietrzak A., Tomasiewicz K., Kanitakis J., Paszkowski T., Dybiec E., Donica H., Wojtowicz A., Terlecki P., Chodorowska G.

Folia Histochemica et Cytobiologica

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2012

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tom 50

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nr 3

5

Possible immunomodulating effect of retinol on cytokines secretion in patients with recurrent furunculosis

80%

Nowicka D., Grywalska E., Hymos A., Mielnik M., Rolinski J.

Archivum Immunologiae et Therapiae Experimentalis

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2018

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tom 66

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nr 1

6

Comparison of effectiveness of parenteral lincomycin/spectinomycin combination and dexpanthenol application in goat kids with contagious ecthyma

80%

Kasap S., Temizel E. M., Karakus A. O., Avci O., Buyukcangaz E., Senturk S., Kavukcu F., Yapici O.

Medycyna Weterynaryjna

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2018

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tom 74

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nr 09

Contagious ecthyma (CE) is a highly contagious viral skin disease that is typically self-limited. Treatment options include topical antiseptics, such as KMNO₄, local antibiotics and systemic antibiotics to prevent secondary skin infections. The aim of this study was to compare the effectiveness of the lincomycin/spectinomycin combination and dexpanthenol (Dxp) in goat kids with CE. The study was conducted at a Saanen dairy goat farm in Bursa, Turkey. The owner of the goat herd inquired at the veterinary hospital about the appearance of granulomatous lesions on the muzzles of goat kids. In this study, 24 goat kids (1-month-olds) were used. All animals were subjected to the same conditions. Blood and papule samples were taken from the animals’ lips, muzzle and buccal mucosa for virological analysis. Swab samples were taken from the lesions for culture and antibiogram. The animals were divided into three groups. Lesions were clinically scored at days 1, 7 and 15 according to a modified previously used scoring system. Goat kids were equally grouped on the basis of lesions on the buccal mucosa, lips and muzzle. The animals in group A received 15 mg/kg lincomycin/ spectinomycin combination (Lypectin®, Vilsan) intramuscularly for 3 consecutive days, group B received 20 mg/kg Dxp (Bepanthen® amp, Bayer, Germany) intramuscularly for 3 consecutive days, and group C received 0.9% NaCl (2 ml), the control treatment. Clinical recoveries were almost equal in all groups, but by day 14, group A showed better recovery than group B and group C. Both study groups also showed better results than the control group for all days. In conclusion, we believe that the lincomycin/spectinomycin combination or dexpanthenol can be useful in the supplementary treatment of CE in goat kids.

7

Bacterial strains colonizing subcutaneous catheters of personal insulin pumps

80%

Nowakowska M., Jarosz-Chobot P., Polanska J., Machnica L.

Polish Journal of Microbiology

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2007

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tom 56

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nr 4

Continuous subcutaneous insulin infusion (CSII) is a commonly used, safe intensive insulin therapy method effective in maintaining normoglycaemia. The disadvantage of CSII are skin infections of the catheter injection site. The aim of the study was to gain insight on the colonization of subcutaneous insulin pump catheters by skin flora and to investigate the correlation between Staphylococcus aureus carrier state (presence in the nose), its presence on the skin and catheter. 141 catheters obtained from 94 children with T1DM and CSII were examined using the semi quantitative culture technique of Maki. The result was positive in 34 examinations (24.1%) in 30 children (31.9%). Most often coagulase negative staphylococci were isolated (30), mainly Staphylococcus epidermidis, 1/3 of the staphylococci were methicillin resistant. S. aureus was detected in 7 examinations in 6 children. S. aureus carrier state was proved in 31.9% of all examined patients, more often in children with a positive catheter culture (41.4%), there were no MRSA. No correlation between S. aureus carrier state and catheter colonization was shown. Statistically significant correlations between: coagulase negative staphylococci presence, including the methicillin resistant strains, on the skin and on the catheter surface (p<0.0001); glycosylated hemoglobin (HbA1c) and bacteria catheter colonization (p = 0.0335) were observed. Subcutaneous catheter colonization by microorganisms often occurs in CSII. Microorganisms found on the skin are the most frequent cause of the subcutaneous catheter infection.

8

First non-conventional veterinary treatment of skin infections with blowfly larvae [Calliphoridae] in Slovakia

80%

Kocisova A., Conkova E., Pistl J., Toporcak J.

Bulletin of the Veterinary Institute in Puławy

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2003

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tom 47

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nr 2

9

Atopic eczema: genetics or environment?

70%

Wuthrich B., Cozzio A., Roll A., Senti G., Kundig T., Schmid-Grendelmeier P.

Annals of Agricultural and Environmental Medicine

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2007

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tom 14

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nr 2

Atopic eczema (AE) is a multifactorial skin disease caused by a variety of factors such as genetic conditions, alterated skin structure, immunologic deviations and environmental factors, among others. There are two main subtypes of AE, i.e. the IgE-associated (“atopic eczema”) and the non-IgE-associated type (“nonatopic eczema”) with different prognosis concerning the development of respiratory diseases (“atopy march”). Recently, it was demonstrated that Filaggrin (= fi lament-aggregating protein, FL) is a major gene for atopic eczema. Filaggrin binds to and aggregates the keratin cytoskeleton in the epidermis. Homozygous FLG mutation leads to complete loss of fi laggrin expression in skin. Half or more of children with moderate to severe AE carry FLG mutations. Moreover, fi laggrin loss-of-function mutations predispose to phenotypes involved in the atopy march. The altered skin structure and a defi ciency in antimicrobial peptides favour colonization with Staphylococcus aureus and yeasts (Malassezia sp.). Sensitization to the yeast occurs almost exclusively in AE patients. S. aureus enterotoxins with superantigenic activity stimulate activation of T cells and macrophages. So far, AE skin lesions are orchestrated by the local tissue expression of proinfl ammatory cytokines and chemokines with activation of T lymphocytes, dendritic cells, macrophages, keratinocytes, mast cells, and eosinophils which lead to the skin infl ammatory responses. From the therapeutic point of view, besides emollients and local corticosteroids, topic immunomodulatory drugs (tacrolimus and pimecrolimus) have substantially improved the treatment of AE.

Ograniczanie wyników

Factors leading to dermatophytosis

NK and NKT-like cells in patients with recurrent furunculosis

Staphylococcus pseudintermedius, both commensal and pathogen

Trichophyton mentagrophytes-associated Majocchi’s granuloma treated with cryotherapy

Possible immunomodulating effect of retinol on cytokines secretion in patients with recurrent furunculosis

Comparison of effectiveness of parenteral lincomycin/spectinomycin combination and dexpanthenol application in goat kids with contagious ecthyma

Bacterial strains colonizing subcutaneous catheters of personal insulin pumps

First non-conventional veterinary treatment of skin infections with blowfly larvae [Calliphoridae] in Slovakia

Atopic eczema: genetics or environment?