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A possible physical interpretation of a discontinuous transition between different red blood cell shapes is given. The red blood cell membrane is considered to consist of the bilayer part and the underlaying membrane skeleton. By taking into consideration that the stable cell shape corresponds to the minimum of the membrane energy, that consists of the bilayer and skeleton elastic energies and of the bilayer-skeleton interaction energy, it is shown that aggregation of the skeleton can cause the discontinuous cell shape transformation from a shape with the bilayer completely underlaid with the skeleton to the shape involving a spherical parent cell with completely underlaid bilayer and spherical daughter vesicles without the skeleton.
It is generally accepted that during the Triassic the composition of tetrapod faunas underwent a series of fundamental transformations, mainly as a result of diversification of archosaurs and decline of therapsids (Benton 1994, 2004, 2006). The last herbivorous basal synapsids, dicynodonts, disappeared from the record in the early Norian of the Americas, about 220 Ma (Langer et al. 2007), being unknown from the Late Triassic of Europe. Here, we report a partially articulated skeleton and isolated bones of a giant rhino−size dicynodont in the Upper Triassic fluvial sediments at Lisowice (Lipie Śląskie clay−pit) in southern Poland. Paleobotanical data indicate an early Rhaetian age for the fauna (Dzik et al. 2008; Niedźwiedzki and Sulej 2008). The dicynodont bones are associated with bones of carnivorous dinosaurs, pterosaurs, as well as capitosaur and plagiosaur amphibians. Dicynodonts were represented in the Germanic Basin throughout the Late Triassic, as proven by findings of smaller dicynodonts in older deposits in the same area, associated there with temnospondyl amphibians. It appears, thus, that the fossil record of tetrapod succession in the Late Triassic was strongly controlled by ecological factors and biased by uneven representation of particular environments. The Lisowice assemblage proves that faunas dominated by dicynodonts did not entirely disappear at least until the end of the Triassic.
The purpose of the study was to analyse the occurrence of the third trochanter and its correlation with the morphology of the human femur. The third trochanter was found in 38 of 622 (6.2%) human femora taken from 3 excavation sites. 36 of these were included in the study and were compared to the femora without the third trochanter. The bones with the third trochanter were characterised by a greater superior sagittal diameter and diaphysis platymetry index as well as a larger greater trochanter. These results suggest that the third trochanter is not a progressive morphological feature of the skeleton. Rather it is connected with an altered gluteal muscle function.
Isopropylantipyrine (IPA, propyphenazone) is a pyrazolone derivative, widely used as an antipyretic and analgesic drug. The aim of the study was to evaluate the influence of propyphenazone on rat development. IPA was administered to pregnant rats from day 8 to day 14 of pregnancy once a day, orally by a stomach tube at doses of 2.10 (R1), 21.0 (R2), and 210.0 mg/kg/day (R3). The dams were sacrificed on day 21 of gestation and corpora luteum, implants, resorptions, and live foetuses were counted. The weight of foetuses and placentas, the length of foetuses and their tails were checked. The foetuses were fixed in alcohol and skeletons were stained with alizarin. There was a statistical difference in body length in R1, R2 and numbers of subcutaneous ecchymose in R1. External and skeletal examination of the foetuses revealed no evidence of teratogenesis. It can be concluded that IPA has no harmful effects on the prenatal development of the rat offspring at doses used in the present study.
Investigation into the bony pelvis of the fruit-eating bat, Eidolon helvum, revealed differences in the pelvic dimensions. The pubic joint of the female consists of interpubic ligament that increased in length until puberty. In the juvenile male Eidolon the pubic joint consists of ligament. Ossification of the interpubic ligament in the male is not an adult phenomenon but begins at the juvenile stage. In the adult the distance from the ischial tuberosity to the iliac crest, from the ischial tuberosity to the medial end of the pubis, and the outlet anteroposterior diameter of the pelvis, were significantly higher in the male than in the female. This indicates that the hip bone in the male is longer in both the vertical (height) and transverse (width) measurements than in the female. The dimensions of the adult pelvic inlet and outlet transverse diameters were significantly higher in the female than in the male. This indicates that the female pelvic canal is wider than the male and this is a consequence of the female interpubic ligament.
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