Wyniki wyszukiwania

1

Skeletopic analysis of the gonadal veins in human foetuses

100%

Szpinda M., Frackiewicz P., Brazis P., Wisniewski M.

Folia Morphologica

|

2005

|

tom 64

|

nr 2

84-88

During ontogenesis an imbalance is observable in the development of the skeletal and vascular systems. By means of anatomical and radiological methods the gonadal veins were studied in relation to the vertebral column in 60 human foetuses of both sexes aged from 4 to 6 months of prenatal life. In male foetuses aged 4–5 months the origin of the gonadal veins projected onto the sacral apex (r₁ = 0.95, r₃ = 0.85), and in 6th month they extended below the vertebral column (r₁’ = 0.80, r₃’ = 0.90). In female foetuses the origin of the gonadal veins in the 4th month projected symmetrically onto S₁ (r₅ = 0.70, r₇ = 0.70). In the 5th month of intrauterine life the origin of the left ovarian vein was found at S₂ (r₇’ = 0.80) and the origin of the right one at S₁–S₂ (r₅’ = 0.80). In the 6th month the origin of the left ovarian vein was located at S₃ (r₇’’ = 0.80) and the right one at S₂–S₃ (r₅’’ = 0.90). The skeletopic analysis of the origin of the gonadal veins demonstrated gender (the origin was higher in females) and syntopic (the origin was higher on the right side) differences (p ≤ 0.05). In foetuses of both sexes aged 4 months of prenatal life the termination of the left gonadal veins projected onto Th₁₂–L₁ (r₄ = 0.85, r₈ = 0.80) and in foetuses aged 5–6 months it projected onto L₁–L₂ (r₄’ = 0.90, r₈’ = 0.95). In both sexes the termination of the gonadal veins on the right side projected constantly onto L₂ (r₂ = 0.90, r₆ = 0.95) from the 4th to the 6th month of intrauterine life. The skeletopic analysis of the termination of the gonadal veins showed syntopic dimorphism (p ≤ 0.05) without gender differences (p > 0.05). On the right side the termination of the gonadal (testicular and ovarian) veins projected constantly onto L₂. On the left side the termination of the left gonadal (testicular and ovarian) veins apparently descended by one vertebra (pseudodescensus).

2

The shape of fetal ossification centers may indicate malformation of vertebral column

84%

Skorzewska A., Grzymislawska M., Bruska M., Lupicka J., Wozniak W.

Acta Biologica Cracoviensia. Series Botanica. Supplement

|

2014

|

tom 56

|

nr 1

3

A comparative study of the effects of genistein, estradiol and raloxifene on the murine skeletal system

67%

Sliwinski L., Folwarczna J., Nowinska B., Cegiela U., Pytlik M., Kaczmarczyk-Sedlak I., Trzeciak H., Trzeciak H. I.

Acta Biochimica Polonica

|

2009

|

tom 56

|

nr 2

261-270

Genistein, a major phytoestrogen of soy, is considered a potential drug for prevention and treatment of postmenopausal osteoporosis. The aim of the present study was to compare the effects of genistein, estradiol and raloxifene on the skeletal system in vivo and in vitro. Genistein (5 mg/kg), estradiol (0.1 mg/kg) or raloxifene hydrochloride (5 mg/kg) were administered daily by a stomach tube to mature ovariectomized Wistar rats for 4 weeks. Bone mass, mineral and calcium content, macrometric parameters and mechanical properties were examined. Also the effects of genistein, estradiol and raloxifene (10-9-10-7 M) on the formation of osteoclasts from neonatal mouse bone marrow cells and the activity of osteoblasts isolated from neonatal mouse calvariae were compared. In vivo, estrogen deficiency resulted in the impairment of bone mineralization and bone mechanical properties. Raloxifene but not estradiol or genistein improved bone mineralization. Estradiol fully normalized the bone mechanical properties, whereas genistein augmented the deleterious effect of estrogen-deficiency on bone strength. In vitro, genistein, estradiol and raloxifene inhibited osteoclast formation from mouse bone marrow cells, decreasing the ratio of RANKL mRNA to osteoprotegerin mRNA expression in osteoblasts. Genistein, but not estradiol or raloxifene, decreased the ratio of alkaline phosphatase mRNA to ectonucleotide pyrophosphatase phosphodiesterase 1 mRNA expression in osteoblasts. This difference may explain the lack of genistein effect on bone mineralization observed in ovariectomized rats in the in vivo study. Concluding, our experiments demonstrated profound differences between the activities of genistein, estradiol and raloxifene towards the osseous tissue in experimental conditions.

4

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Badania nad wiekiem rozwojowym dzieci szkolnych na podstawie oceny zdjęć fluorograficznych kośćca

67%

Kopczynska J.

Roczniki Państwowego Zakładu Higieny

|

1959

|

tom 10

|

nr 4

5

Changing magnetic fields in the treatment of compressive fractures in the cervical spine - case description

67%

Pasek J., Kwiatek S., Pasek T., Kozlowska-Kwiatek I., Kwiatek P., Sieron-Stoltny K., Sieron A.

Polish Journal of Environmental Studies

|

2009

|

tom 18

|

nr 3

429-433

Many people spend about 80% of their free time practicing sports, including skiing, which in many cases can cause changes in the skeletal system, muscular system and other organs. The aim of this article is to discuss the treatment of a 25-year-old man who suffered a compressive fracture of the C6 vertebra with paresis of the ulnar nerve. The treatment used physiotherapy with changing magnetic fields (magnetostimulation, magnetolaserotherapy, kinesitherapy exercises) with good effects. On the basis of the results we discovered that these treatment methods can accelerate the time of treatment and increase quality of life.

6

Effect of long-term aluminium chloride intoxication on selected biochemical parameters and oxidative-antioxidative balance in experimental animals

59%

Kowalczyk E., Kopff A., Kedziora J., Blaszczyk J., Kopff M., Niedworok J., Fijalkowski P.

Polish Journal of Environmental Studies

|

2004

|

tom 13

|

nr 1

Aluminium is numbered among trace elements with a moderate toxic effect on living organisms. We have attempted to assess the influence of long-term aluminium chloride intake on the biochemical parameters and oxidative stress biomarkers in experimental animals. Three months’ administration of aluminium chloride in drinking water at a dose of 80 mg/l significantly elevated blood serum urea and creatinine concentration, as well as oxidative stress biomarkers such as: TBARS content in erythrocytes hemolysate, protein carbonyl groups concentration and 8-hydroxy-2’-deoxyguanosine excretion with urine.

Ograniczanie wyników

Skeletopic analysis of the gonadal veins in human foetuses

The shape of fetal ossification centers may indicate malformation of vertebral column

A comparative study of the effects of genistein, estradiol and raloxifene on the murine skeletal system

Badania nad wiekiem rozwojowym dzieci szkolnych na podstawie oceny zdjęć fluorograficznych kośćca

Changing magnetic fields in the treatment of compressive fractures in the cervical spine - case description

Effect of long-term aluminium chloride intoxication on selected biochemical parameters and oxidative-antioxidative balance in experimental animals