Wyniki wyszukiwania

1

Increased levels of interleukin-12 and interleukin-18 in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis

100%

Mroz R. M., Korniluk M., Stasiak-Barmuta A., Chyczewska E.

Journal of Physiology and Pharmacology. Supplement

|

2008

|

tom 59

|

nr 6

507-513

2

Cellular components of the bronchoalveolar lavage correlate with lung function impairment and extrapulmonary involvement markers in active sarcoidosis

100%

Chorostowska-Wynimko J., Lesniewska-Radomska D., Krychniak-Soszka A., Remiszewski P., Szopinski J., Wesolowski S., Kus J., Skopinska-Rozewska E.

Journal of Physiology and Pharmacology. Supplement

|

2004

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tom 55

|

nr 3

41-47

Sarcoidosis is a chronic inflammatory multiorgan disease of unknown origin. Our previous study demonstrated a significant correlation between the relative count of nonCD4+, nonCD8+ lymphocytes in bronchoalveolar lavage of active sarcoidosis patients and proangiogenic activity of BAL homogenates. The aim of the present study was to evaluate in a group of 40 patients with active sarcoidosis the possible relationship between the intensity of alveolitis, particularly the nonCD4+, nonCD8+ lymphocyte subset, and other parameters characterizing the level of pulmonary (lung function tests) and extrapulmonary (spleen longitudinal dimension) disease activity. We found that the relative count of nonCD4+, nonCD8+ lymphocytes in BAL correlated positively with spleen size (r=0.50, P<0.01) and negatively with static compliance (r=0.43, P<0.05). We concluded that the lymphocytes belonging to the nonCD4+nonCD8+ subset participate in the inflammatory process in sarcoidosis. However, more detailed phenotypic and functional characteristics of this cellular population are needed.

3

Induced sputum in patients with interstitial lung disease: a non-invasive surrogate for certain parameters in bronchoalveolar lavage fluid

84%

Sobiecka M., Kus J., Demkow U., Filewska M., Jozwik A., Radwan-Rohrenschef P., Chorostowska-Wynimko J.

Journal of Physiology and Pharmacology. Supplement

|

2008

|

tom 59

|

nr 6

645-657

4

Differential inflammatory microRNA and cytokine expression in pulmonary sarcoidosis

84%

Jazwa A., Kasper L., Bak M., Sobczak M., Szade K., Jozkowicz A., Sladek K., Dulak J.

Archivum Immunologiae et Therapiae Experimentalis

|

2015

|

tom 63

|

nr 2

5

Involvement of microRNAs in the inflammatory pathways of pulmonary sarcoidosis

84%

Bak M., Jazwa A., Kasper L., Kachamakova-Trojanowska N., Jozkowicz A., Skladek K., Dulak J.

Journal of Physiology and Pharmacology

|

2015

|

tom 66

|

nr 5

6

Concentration of surfactant protein D, Clara cell protein CC-16 and IL-10 bronchoalveolar lavage [BAL] in patients with sarcoidosis, hypersensitivity pneumonitis and idiopathic pulmonary fibrosis

67%

Kucejko W., Chyczewska E., Naumnik W., Ossolinska M.

Folia Histochemica et Cytobiologica

|

2009

|

tom 47

|

nr 2

225-230

7

Ion mobility spectrometry in the diagnosis of sarcoidosis: results of a feasibility study

67%

Westhoff M., Litterst P., Freitag L., Baumbach J. I.

Journal of Physiology and Pharmacology. Supplement

|

2007

|

tom 58

|

nr 5

8

Comparison of induced sputum and bronchoalveolar lavage fluid cell profile during the treatment of pulmonary sarcoidosis

67%

Mroz R. M., Korniluk M., Stasiak-Barmuta A., Chyczewska E.

Journal of Physiology and Pharmacology. Supplement

|

2007

|

tom 58

|

nr 5

9

Inflammatory markers in the exhaled breath condensate of patients with pulmonary sarcoidosis

67%

Rozy A., Czerniawska J., Stepniewska A., Wozbinska B., Goljan A., Puscinska E., Gorecka D., Chorostowska-Wynimko J.

Journal of Physiology and Pharmacology. Supplement

|

2006

|

tom 57

|

nr 4

335-340

Pulmonary sarcoidosis may progress to fibrosis in some patients, so that close monitoring of its activity is essential for recommending clinical strategy. Examination of ariway inflammatory markers in bronchoalveolar lavage (BAL) is one of the methods applied to assess the disease severity. Recently, the expired breath condensate (EBC) has become another source of cytokines and mediators. In sarcoidosis, except for NO and oxidative stress markers, no other mediators have yet been estimated in the exhaled air. In the present study we attempted to answer the question of whether airway inflammatory markers in pulmonary sarcoidosis patients might be assessable in EBC and to what extend these markers might reflect the disease activity in the lungs IL-6, TNF-alpha, PAI-1, and IGF-1 were measured by Elisa method in EBC and BALF samples from 9 patients with newly-diagnosed pulmonary sarcoidosis. TNF-alpha, IGF-1, and PAI-1 levels in EBC and BAL samples were comparable and closely positively correlated [TNF-alpha (r=0.79, P<0.001), IGF-1 (r=0.94, P<0.001), and PAI-1 (r=0.81, P<0.001)]. In contrast, IL-6 concentration in EBC was significantly lower compared with that in BALF, while the correlation between both materials was negative (r=-0.47, P<0.05). An important distinction in IL-6 performance, which might explain this inconsistency, is its tendency to form more complex molecular forms of a higher weight than that of other cytokines. Our study shows that EBC reflects cytokine production in the lung as effectively as BALF, providing that the characteristics of proteins evaluated allow their easy transfer into the exhaled air. Further studies are required before accepting EBC samples as an equivalent to BALF.

10

Modulatory effect of sera from sarcoidosis patients on mononuclear cell-induced angiogenesis

67%

Zielonka T. M., Demkow U., Bialas B., Filewska M., Zycinska K., Radzikowska E., Szopinski J., Skopinska-Rozewska E.

Journal of Physiology and Pharmacology. Supplement

|

2007

|

tom 58

|

nr 5

11

HLA-A, B, C antigens in pulmonary sarcoidosis in Polish population

67%

Dubaniewicz A., Szczerkowska Z.

Archivum Immunologiae et Therapiae Experimentalis

|

1999

|

tom 47

|

nr 1

12

Expression of insulin-like growth factor-I [IGF-I] in alveolar macrophages and lymphocytes obtained by bronchoalveolar lavage [BAL] in interstitial lung diseases [ILD]. Assessment of IGF-I as a potential local mitogen and antiapoptotic cytokine

67%

Kopinski P., Sladek K., Szczeklik J., Soja J., Szlubowski A., Balicka-Slusarczyk B., Lackowska B., Plato M., Szpechcinski A.

Folia Histochemica et Cytobiologica

|

2006

|

tom 44

|

nr 4

13

Przegląd metod leczenia sarkoidów u koni

51%

Niedzwiedz A.

Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii

|

2014

|

tom 09

|

nr 1

Ograniczanie wyników

Increased levels of interleukin-12 and interleukin-18 in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis

Cellular components of the bronchoalveolar lavage correlate with lung function impairment and extrapulmonary involvement markers in active sarcoidosis

Induced sputum in patients with interstitial lung disease: a non-invasive surrogate for certain parameters in bronchoalveolar lavage fluid

Differential inflammatory microRNA and cytokine expression in pulmonary sarcoidosis

Involvement of microRNAs in the inflammatory pathways of pulmonary sarcoidosis

Concentration of surfactant protein D, Clara cell protein CC-16 and IL-10 bronchoalveolar lavage [BAL] in patients with sarcoidosis, hypersensitivity pneumonitis and idiopathic pulmonary fibrosis

Ion mobility spectrometry in the diagnosis of sarcoidosis: results of a feasibility study

Comparison of induced sputum and bronchoalveolar lavage fluid cell profile during the treatment of pulmonary sarcoidosis

Inflammatory markers in the exhaled breath condensate of patients with pulmonary sarcoidosis

Modulatory effect of sera from sarcoidosis patients on mononuclear cell-induced angiogenesis

HLA-A, B, C antigens in pulmonary sarcoidosis in Polish population

Expression of insulin-like growth factor-I [IGF-I] in alveolar macrophages and lymphocytes obtained by bronchoalveolar lavage [BAL] in interstitial lung diseases [ILD]. Assessment of IGF-I as a potential local mitogen and antiapoptotic cytokine

Przegląd metod leczenia sarkoidów u koni