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Avian reoviruses are members of the Orthoreovirus genus in the Reoviridae family. They were first isolated from the respiratory tract of chickens with chronic respiratory disease. Reovirus infections can spread horizontally by direct contact among infected birds or indirectly by water, feed and feces. In the case of chickens the viruses cause arthritis/tenosynovitis, reovirosis, pericarditis, miocarditis, malabsorption syndrome, enteritis, hepatitis, atrophy of the bursa Fabricii and thymus, and acute and chronic respiratory tract diseases. Reoviruses are also isolated from turkeys with arthritis and malabsorption syndrome. In the case of geese and Muscovy ducks they cause diarrhorea and hepatitis. The viruses have an immunosuppressive ability and are frequently found in chickens with latent infections that were initially clinically normal. Prevention and control are achieved through vaccinating the parent flocks and broilers, as well as by disinfection.
The aim of the study was to determine the influence of some pathogens on the serum level and dynamics of chicken cystatin and a1-protease inhibitor. The experiment was carried out on 150 Starbro chickens that were randomly selected into 6 groups. Group I was the control, group II and III were infected with REO virus and Marek's disease virus, group IV with invasive Eimeria oocysts, and V and VI with E. coli and S. aureus respectively. The level of chicken cystatin was determined by ELISA test and a1-protease inhibitor as an antitrypsin capacity. It was demonstrated that the concentration of chicken cystatin increased in chickens with the virus infection REO and MDV by about 54% and 29%, while with E. coli and S. aureus by 43%. The smallest changes, observed in chickens infected with Eimeria oocyst, amounted to 16%. In contrast, the authors only observed an increase of the level a1-protease inhibitor in coccidiosis. The authors postulate that chicken cystatin is more useful as a diagnostic parameter than a1-protease inhibitor in the analysed diseases.
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