Twenty two scab-resistant apple cultivars, harvested in the 2007 and 2008 seasons, were analysed for phenolic compounds content and polyphenol oxidase (PPO) activity. Tyrosine content was determined in the raw juices of five selected cultivars. The results showed substantial differences in the composition between the investigated apple cultivars, particularly in the phenolic compounds contents. Their total polyphenol content ranged from 161.9 to 882.4 mg/kg f.w., with hydroxycinnamic acids as the main phenolic compounds. The level of PPO activity ranged from 5 to 240 U/g f.w. Almost half of the 22 cultivars show PPO activity below 50 U/g f.w. 'Angold', 'Selena' and 'Gold Milenium' showed the highest PPO activity; between 125-133 U/g f.w. 'Rebella', 'Sampion', 'Topaz', 'Rewena', 'Enterprise' and 'Gerlinde' showed the lowest PPO activity. Statistical analysis showed no correlation between PPO activity and total polyphenol content or hydroxycinnamic acids. No correlation can be confirmed between PPO activity and tyrosine content.