Wyniki wyszukiwania

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Signal-averaged P-wave ECG as a marker of atrial electrical instability in patients with right ventricular dysfunction

100%

Schueller P. O., Steiner S., Enayat M., Schannwell C. M., Hennersdorf M., Strauer B. E.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

2

Effects of prenatal hypoxia on pulmonary vascular reactivity in chickens prone to pulmonary hypertension

100%

Zoer B., Kessels L., Vereijken A., De Mey J. G. R., Bruggeman V., Decuypere E., Blanco C. E., Villamor E.

Journal of Physiology and Pharmacology

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2009

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tom 60

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nr 1

119-130

Among chickens, meat-producing broiler strains are highly prone to develop severe pulmonary hypertension (PH) that is accompanied by endothelial dysfunction in the conduit extrapulmonary arteries. We hypothesized that exposure to chronic prenatal mild hypoxia would accelerate PH and endothelial dysfunction in smaller intrapulpulmonary arteries from broiler chickens. Fertilized broiler and layer (White Leghorn, WL) eggs were incubated under normoxic or hypoxic conditions. Endothelium-dependent (tested with acetylcholine, ACh ) and -independent (tested with sodium nitroprusside, SNP) relaxations of the caudomedial intrapulmonary artery were studied on fetal day 19 and at 2 weeks post-hatch. The response to acute hypoxia in vitro was also studied in the 2 wk-old vessels. Relaxations induced by ACh and SNP were similar in broiler and layer chickens and were unaffected by chronic mild hypoxia during incubation. However, during in vitro acute hypoxia the broiler arteries showed a markedly enhanced contraction. Chronic prenatal hypoxia did not affect the response of intrapulmonary arteries to acute hypoxia. We conclude that early endothelial dysfunction is not present in the small pulmonary arteries of fast-growing broilers after incubation under normoxic or hypoxic conditions. The higher susceptibility of the broiler pulmonary arteries to acute hypoxia might, at least partially, explain the higher susceptibility to PH.

3

Left ventricular dysfunction in patients with interstitial lung diseases referred for lung transplantation

100%

Jastrzebski D., Nowak J., Ziora D., Wojarski J., Czyzewski D., Kozielski J., Polonski L., Zembala M.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

4

Effects of tadalafil (PDE5 inhibitor) and roflumilast (PGE4 inhibitor) on airway reactivity and markers of inflammation in ovalbumin-induced airway hyperresponsiveness in guinea pigs

80%

Mokry J., Urbanova A., Medvedova I., Kertys M., Mikolka P., Kosutova P., Mokra D.

Journal of Physiology and Pharmacology

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2017

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tom 68

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nr 5

5

Diagnostics in pulmonary hypertension

80%

Schannewll C. M., Steiner S., Strauer B.-E.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

6

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Role of thromboxane A2 and platelet activating factor in early haemodynamic response to lipopolysaccharide in rats

80%

Bochenski J., Chlopicki S., Gryglewski R. J.

Journal of Physiology and Pharmacology

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1999

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tom 50

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nr 2

7

Increased pneumotoxicity of lipopolysaccharide from E.coli in nitric oxide deficient blood-perfused rat lungs

80%

Bartus J. B., Chlopicki S., Gryglewski R. J.

Journal of Physiology and Pharmacology

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1997

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tom 48

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nr 4

Ograniczanie wyników

Signal-averaged P-wave ECG as a marker of atrial electrical instability in patients with right ventricular dysfunction

Effects of prenatal hypoxia on pulmonary vascular reactivity in chickens prone to pulmonary hypertension

Left ventricular dysfunction in patients with interstitial lung diseases referred for lung transplantation

Effects of tadalafil (PDE5 inhibitor) and roflumilast (PGE4 inhibitor) on airway reactivity and markers of inflammation in ovalbumin-induced airway hyperresponsiveness in guinea pigs

Diagnostics in pulmonary hypertension

Role of thromboxane A2 and platelet activating factor in early haemodynamic response to lipopolysaccharide in rats

Increased pneumotoxicity of lipopolysaccharide from E.coli in nitric oxide deficient blood-perfused rat lungs