Wyniki wyszukiwania

1

Lactoferrin regulates proliferative response of human peripheral blood mononuclear cells to phytohemagglutinin and mixed lymphocyte reaction

100%

Zimecki M., Stepniak D., Szynol A., Kruzel M. L.

Archivum Immunologiae et Therapiae Experimentalis

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2001

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tom 49

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nr 2

2

The effect of Rhodiola quadrifida extracts on cellular immunity in mice and rats

67%

Skopinska-Rozewska E., Wojcik R., Siwicki A. K., Sommer E., Wasiutynski A., Furmanowa M., Malinowski M., Mazurkiewicz M.

Polish Journal of Veterinary Sciences

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2008

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tom 11

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nr 2

105-111

Rhodiola quadrifida (Rq) roots and rhizomes are traditionally used in Asia as a tonic, adaptogen, antidepressant and anti-inflammatory drug. The aim of this work was to study the in vivo effect of aqueous and 50% hydro-alcoholic extracts of Rq rhizomes on some parameters of cellular immunity in mice and rats. The metabolic activity of blood phagocyting cells was determined based on the measurement of intracellular respiratory burst after stimulation by PMA in RBA test. Potential bactericidal activity of phagocyting cells was determined in isolated blood leukocytes stimulated with killed microorganisms, according to the PKA test. Proliferative response of lymphocytes stimulated by mitogen concanavaline A (ConA) or lipopolysaccharide (LPS) were determined by MTT assay. Both extracts stimulated granulocytes activity in vitro and increased lymphocyte response to mitogens. The ability of parental strain mice lymphocytes to induce local cutaneous graft-ver- sus-host reaction (GVH) in F1 hybrids was stimulated by 50% hydro-alcoholic extract only.

3

Immunological status of septic and trauma patients. II. Proliferative response and production of interleukin 6 and tumor necrosis factor alpha by peripheral blood mononuclear cells from septic survivor, nonsurvivor and trauma patients: a correlation with the survival rate

67%

Adamik B., Zimecki M., Wlaszczyk A., Kubler A.

Archivum Immunologiae et Therapiae Experimentalis

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1997

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tom 45

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nr 4

4

Up-regulation of spermidine-spermine N1-acetyltransferase [SSAT] expression is a part of proliferative but not anabolic response of mouse kidney

59%

Dudkowska M., Stachurska A., Grzelakowska-Sztabert B., Manteuffel-Cymborowska M.

Acta Biochimica Polonica

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2002

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tom 49

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nr 4

A differential expression pattern of spermidine/spermine N1-acetyltransferase (SSAT), the enzyme critical to proper homeostasis of cellular polyamines, is reported in mouse kidney undergoing hyperplasia and hypertrophy. We have shown that SSAT activity and SSAT mRNA are significantly induced by antifolate CB 3717 and folate that evoke a drug-injury-dependent hyperplasia. In contrast, SSAT activity is down-regulated in the testosterone-induced hypertrophic kidney, while SSAT mRNA is positively controlled by this androgen. Catecholamine depletion evoked by reser- pine drastically decreases the folate-induced activity of «S-adenosylmethionine decar- boxylase (AdoMetDC), which limits polyamine biosynthesis, but has no effect on SSAT activity augmented by CB 3717. Our results document that the increased SSAT expression solely accompanies the proliferative response of mouse kidney, and suggest the importance of post-transcriptional regulation to the control of SSAT activity in both hyperplastic and hypertrophic experimental models.

Ograniczanie wyników

2 Archivum Immunologiae et Therapiae Experimentalis

1 Acta Biochimica Polonica

1 Polish Journal of Veterinary Sciences

2 Zimecki M.

1 Adamik B.

1 Dudkowska M.

1 Furmanowa M.

1 Grzelakowska-Sztabert B.

1 Kruzel M. L.

1 Kubler A.

1 Malinowski M.

1 Manteuffel-Cymborowska M.

1 Mazurkiewicz M.

1 Siwicki A. K.

1 Skopinska-Rozewska E.

1 Sommer E.

1 Stachurska A.

1 Stepniak D.

1 Szynol A.

1 Wasiutynski A.

1 Wlaszczyk A.

1 Wojcik R.

1 2008

1 2002

1 2001

1 1997

Lactoferrin regulates proliferative response of human peripheral blood mononuclear cells to phytohemagglutinin and mixed lymphocyte reaction

The effect of Rhodiola quadrifida extracts on cellular immunity in mice and rats

Immunological status of septic and trauma patients. II. Proliferative response and production of interleukin 6 and tumor necrosis factor alpha by peripheral blood mononuclear cells from septic survivor, nonsurvivor and trauma patients: a correlation with the survival rate

Up-regulation of spermidine-spermine N1-acetyltransferase [SSAT] expression is a part of proliferative but not anabolic response of mouse kidney