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1
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

The influence of alfalfa saponins and mustard glucosinolates on the fertility of Colorado potato beetles [Leptinotarsa decemlineata Say]

100%
Waligora D.
Journal of Plant Protection Research
|
2002
|
tom 42
|
nr 4
2

The influence of solvent choice on the recovery of phytogenic phenolic compounds extracted from plant material

100%
Jaroszynska J.
Polish Journal of Environmental Studies
|
2003
|
tom 12
|
nr 4
Sometimes, the preparation of a plant sample to GC analysis undergoes the stage of drying plant ex-tract from the solvent, and subsequently the repeated extraction of the dry residue in a different solvent. The purpose of this procedure is to separate the studied phenolic compounds from the matrix. This paper presents the results of the research into the effect of the type of solvent used in the proceeding (methanol, water, acetone, diethyl ether or chloroform) on the size of losses in the phenolic compounds during such a procedure. It has been noted that the greatest recovery appears in cases of methanol and acetone, whereas water may be the source of considerable losses in the compounds during the preparation of the plant sample for analysis.
3

Terpene accumulation in muscle and fatty tissues of calves supplemented with essential oils

84%
Serrano E., Cornu A., Kondjoyan N., Figueredo G., Agabriel J., Micol D.
Journal of Animal and Feed Sciences
|
2007
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tom 16
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nr 2
168-179
4

Evaluation of the lipophilicity and stability of phenolic compounds in herbal extracts

84%
Materska M.
Acta Scientiarum Polonorum. Technologia Alimentaria
|
2010
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tom 09
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nr 1
61-69
Background. Phenolic compounds are secondary plant metabolites, which occur in different parts of cell, according to they lipophilicity. The objective of this study was to determine differences in the content and stability of those compounds in herbal extract fractions marked by increasing lipophilicity. Material and methods. Eight herbal plants were analysed: basil, savory, lovage, lemon balm, peppermint, parsley, oregano and sage. Extracts were prepared from fresh plants harvested in late July, and they were separated into aqueous fractions and isolated with a 40% and 70% methanol solution on Cl8 silica gel. The total content of phenolics was determined using the Folin-Ciocalteu method directly after preparation and after three and six months of storage. Results. The stability of fresh herb extracts varied subject to plant species. The lemon balm leaf extract was most abundant in phenolic compounds and showed the highest polyphenol concentrations throughout the storage period. The greatest drop in phenolic compound levels was observed in parsley extracts. Following the separation of raw extracts into three fractions, the highest phenolic compound concentrations were noted in fractions isolated with a 40% methanol solution. The most dynamic changes in polyphenol content were reported in the initial period of storage (three months) regardless of the fraction’s lipophilicity. Compounds that were not degraded after this period were marked by high stability. Conclusions. Phenolic compounds found in herbal plants are hydrophilic to lipophilic substances which are stable compounds regardless of their affinity for water.
5
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Flavonoids - food sources and health benefits

67%
Kozlowska A., Szostak-Wegierek D.
Roczniki Państwowego Zakładu Higieny
|
2014
|
tom 65
|
nr 2
Flavonoids are a group of bioactive compounds that are extensively found in foodstuffs of plant origin. Their regular consumption is associated with reduced risk of a number of chronic diseases, including cancer, cardiovascular disease (CVD) and neurodegenerative disorders. Flavonoids are classified into subgroups based on their chemical structure: flavanones, flavones, flavonols, flavan-3-ols, anthocyanins and isoflavones. Their actions at the molecular level include antioxidant effects, as well the ability to modulate several key enzymatic pathways. The growing body of scientific evidence indicates that flavonoids play a beneficial role in disease prevention, however further clinical and epidemiological trials are greatly needed. Among dietary sources of flavonoids there are fruits, vegetables, nuts, seeds and spices. Consumption of these substances with diet appears to be safe. It seems that a diet rich in flavonoids is beneficial and its promotion is thus justifiable.
6

Yielding and quality of garlic leaves. Part II. Primary metabolites

67%
Dyduch J., Najda A.
Electronic Journal of Polish Agricultural Universities. Series: Horticulture
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2011
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tom 14
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nr 2
7

Lclet 4 enhances pro-apoptotic and anti-invasive effects of mitoxantrone on human prostate cancer cells - in vitro study

67%
Koczurkiewicz P., Podolak I., Wojcik K. A., Galanty A., Madeja Z., Michalik M., Czyz J.
Acta Biochimica Polonica
|
2013
|
tom 60
|
nr 3
Triterpene saponosides are widely distributed plant secondary metabolites characterized by relatively low systemic cytotoxicity and a range of biological activities. These include anti-inflammatory, antimicrobial, vasoprotective and antitumor properties. In particular, the ability of saponins to enhance the cytotoxicity of chemotherapeutic drugs opened perspectives for their application in combined cancer chemotherapy. Here, we used human prostate cancer DU-145 cells as an in vitro model to elucidate the synergy of the interactions between biological activities of an oleanane type 13β,28-epoxy triterpene saponoside (Lclet 4) and mitoxantrone, which is a cytostatic drug commonly used in prostate cancer therapy. No cytotoxic or pro-apoptotic effect of Lclet 4 and mitoxantrone administered at the concentrations between 0.05 and 0.1 µg/ml could be seen. In contrast, cocktails of these agents exerted synergistic pro-apoptotic effects, accompanied by the activation of the caspase 3/7 system. This effect was paralleled by attenuating effects of Lclet 4/mitoxantrone cocktails on the invasive potential, metalloproteinase expression and motility of DU-145 cells. Multifaceted and additive effects of Lclet 4 and mitoxantrone on basic cellular traits crucial for prostate cancer progression indicate that the combined application of both agents at systemically neutral concentrations may provide the basis for new promising strategies of prostate cancer chemotherapy.
8

New antibacterial therapeutics and strategies

67%
Kurek A., Grudniak A., Kraczkiewicz-Dowjat A., Wolska K.
Polish Journal of Microbiology
|
2011
|
tom 60
|
nr 1
Studies on new antibacterial therapeutics and strategies are currently being conducted in many microbiological, pharmaceutical and biochemical laboratories. The antibacterial activity of plant-derived compounds as well as silver and gold nanoparticles is the subject of this minireview. The application of photodynamic therapy is also discussed.
9
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Digestion and absorption of phenolic compounds assessed by in vitro simulation methods. A review

67%
Tarko T., Duda-Chodak A., Zajac N.
Roczniki Państwowego Zakładu Higieny
|
2013
|
tom 64
|
nr 2
Phenolic compounds are a group of key plant metabolites found abundantly in fruit and vegetables. Because of their antioxidant properties, they play a significant role in preventing various degenerative illnesses, tumours or cardiovascular disease. In nature, they are present in foods mainly as esters, glycosides and polymers which need to undergo enzymatic hydrolysis in the digestive tract or by the gut microflora before becoming absorbed. The biological properties of these phenolic compounds undergoing this degradation, are thus governed by their absorption as well as metabolism. Many methods are used to assess the rates and the degrees to which these substances are digested and absorbed, both in vivo and in vitro ones, where the former are the most reliable, although they suffer from various limitations. For this reason, many in vitro models have now arisen to simulate the function of human digestion in the attempt to faithfully re-create real-life conditions. Mechanisms of polyphenols absorption have been principally studied by intestinal epithelial cell models, in particular, those using the Caco-2 cell line.
10

Effect of indole-3-carbinol on detoxification enzymes and lipid metabolism

67%
Bialik I., Okulicz M., Chichlowska J.
Acta Scientiarum Polonorum. Medicina Veterinaria
|
2002
|
tom 01
|
nr 2
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