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1

Ultrastrukturalne zmiany w oligodendrocytach istoty szarej środkowej u starych szczurów

100%
Wawrzyniak-Gacek A., Jaworska-Adamu J.
Medycyna Weterynaryjna
|
2012
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tom 68
|
nr 06
The structure and functions of the oligodendrocytes in different areas of the brain in the normal process of aging in mammals is poorly known. The purpose of this study was to investigate three types of oligodendrocytes, their ultrastructure as well as morphology of myelin sheaths of nerve fibers in the central gray matter (substantia grisea centralis-SGC). The study was conducted on adult rats, 25-week-old and140-week-old rats. The animals were perfused with fixative through the left ventricle and the midbrain containing SGC were collected. Ultrathin sections were observed and photographed in an electron microscope. In both tested age groups oligodendrocytes were usually arranged in pairs. In adult rats, the SGC survey revealed a clear advantage and medium oligodenrocytów, and, rarely, dark cells with normal ultrastructure. In old rats, oligodendrocytes were dominated by medium and dark cytoplasm and less commonly with clear cells. The cytoplasm of the few bright and medium oligodendrocytes expressed the morphological changes manifested by the presence of varying electron densities and size of inclusions and the insulation of nerve fibers were also changed. The presence of the few bright oligodendrocytes in the SGC in old rats suggests that a few of their young forms of progenitor cells may arise, as in other areas of the brain normally aging in mammals. These new cells may participate in remielinization nerve fibers affecting the proper connections SGC with other brain areas.
2

Badania morfologiczne oligodendrocytów istoty szarej środkowej u starych szczurów

100%
Wawrzyniak-Gacek A., Jaworska-Adamu J.
Medycyna Weterynaryjna
|
2013
|
tom 69
|
nr 01
Currently the structure and function of oligodendrocytes in the central nervous system (cns) in young individuals is known; however, there is no information about their morphology in the central gray matter (substantia grisea centralis-SGC) in old animals. The aim of this study was to investigate the morphology of oligodendrocytes in the semithin SGC sections of 6-month (5 pcs) and 3-year-old (5 pcs) male Wistar rats. The animals were anaesthetized with ketamine, perfused with fixative through the left ventricle, and the midbrains containing SGC were taken. Semithin sections were analyzed morphologically and photographs were made in light microscope Axiolab (Zeiss). In the semithin sections of the SGC of 6-month-old adult rats oligodendrocytes with mostly light and medium density cytoplasm were observed. Oligodendrocytes were located by different structures: blood vessels, neurons and astrocytes. Sometimes two cells with dark cytoplasm were side by side or near oligodendrocytes with a medium cytoplasm density. In old male rats oligodendrocytes with dark cytoplasm located at the capillary blood vessels, neurons and astrocytes were dominant in the SGC. Cells with light cytoplasm, which occurred mainly in blood vessels, were rarely encountered. The results indicate that in the SGC of 3-years-old individuals older forms with a dark cytoplasm are dominant, in contrast to 6-month-old rats which have younger oligodendrocytes with light cytoplasm.
3
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Glej - wróg czy przyjaciel?

100%
Mika J.
Wszechświat
|
2014
|
tom 115
|
nr 01-03
4
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Astrocyty a intelekt

80%
Smialowska M., Domin H.
Wszechświat
|
2015
|
tom 116
|
nr 07-09
5

Nieznana połowa mózgu

80%
Orzylowska-Sliwinska O.
Wiedza i Życie
|
2015
|
nr 01
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