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1

Determination of nystatin in honey by liquid chromatography coupled with mass spectrometry

100%
Cepurnieks G., Bartkevics V., Zeile Z.
Polish Journal of Food and Nutrition Sciences
|
2011
|
tom 61
|
nr Suppl.1
2
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Yeasts isolated from frequently in-patients and out-patients

84%
Dynowska M., Ejdys E., Biedunkiewicz A., Kubiak D., Sucharzewska E., Roslan M.
Annals of Parasitology
|
2014
|
tom 60
|
nr 3
The paper is a part of a general mycological monitoring study of nosocomial infections. Differences in the species composition and drug resistance of fungi isolated from in-patients and out-patients prompted an analysis of this topic. The studies were conducted with fungi from the collection of the Department of Mycology, University of Warmia and Mazury in Olsztyn, that were isolated from the oral cavity, sputum, bronchoscopic fluid, anus and skin from 100 in-patients and 100 out-patients. Laboratory analyses, including species categorization of fungi, were performed according to routine mycological diagnostics. Drug sensitivity to fluconazole and nystatin was tested with the disc diffusion method. In the group of in-patients, a wider taxonomic diversity of fungi (12 species) was found in comparison with the out-patients (7 species) and 31 cases of multifocal infections were recorded, while in the second group the number of the latter was only six. In all patients, C. albicans were predominant, constituting the largest proportion in focal infections in all patients and in multifocal infections in the in-patients. In the latter, over a half of the examined individuals were resistant to fluconazole (C. glabrata and C. krusei – 80%, C. tropicalis and S. capsularis – 60%, C. guilliermondii – 50%) and nystatin (T. beigelii – 80%, C. krusei and C. tropicalis – 50%). Substantially lower drug resistance of fungi was recorded in the out-patients. The hospital environment is an abundant reservoir of different fungal species with significantly greater expansiveness and aggressiveness compared to the environment outside a hospital.
3

The response of horse erythrocytes to polyene antibiotics

84%
Knopik-Skrocka A., Buldanczyk A.
Biological Letters
|
2004
|
tom 41
|
nr 1
4

A kinetics study of pig erythrocyte hemolysis induced by polyene antibiotics

84%
Knopik-Skrocka A., Bielawski J., Glab M., Klafaczynska A., Wulkiewicz M.
Cellular and Molecular Biology Letters
|
2003
|
tom 08
|
nr 2
The kinetics of the hemolysis induced by filipin is of the damage type, indicating the formation of large nonselective perforations of erythrocyte membranes. The process is relatively independent of the ionic composition of the incubation medium, and the differences between the hemolysis induced by filipin in pig and human erythrocytes are not significant. In a sucrose medium, filipin-induced hemolysis is inhibited in humans, whereas it is stimulated in pig erythrocytes. It is suggested that low ionic strength is the reason for the different modifications of complexation of filipin in pig and human erythrocyte membranes in a sucrose medium. The kinetics of the hemolysis induced in pig erythrocytes by amphotericin B and nystatin is of the permeability type, indicating the formation of selective channels in erythrocyte membranes and colloid osmotic hemolysis. The rate of the hemolysis, which is high in a KCl medium, is decreased in all the other media tested (CaCl2, MgCl2, potassium phosphate buffer, K2S04, sucrose), although there are no changes in the kinetics of hemolysis. The results are interpreted as the formation of highly selective channels at a low concentration of the antibiotics. At increasing concentrations, channels of decreasing selectivity occur. The resistances of pig erythrocytes to amphotericin B and nystatin are lower than those of human erythrocytes.
5

Antifungal susceptibility of yeasts isolated from secrection of inflamed mammary glands in cows

67%
Wawron W., Bochniarz M., Dabrowski R.
Polish Journal of Veterinary Sciences
|
2010
|
tom 13
|
nr 3
6

Wplyw antybiotykow na eksplantaty truskawki w kulturach in vitro

51%
Kowalik M., Grodek M.
Progress in Plant Protection
|
2007
|
tom 47
|
nr 4
167-171
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