Wyniki wyszukiwania

1

Respiratory burst of the neutrophils in ischemic heart disease patients

100%

Baj Z., Kantorski J., Kowalski J., Kosmider M., Tchorzewski H., Pawlicki L., Ciecwierz J.

Current Topics in Biophysics

|

1994

|

tom 18

|

nr 2

2

Step and ramp induction of myocardial ischemia: comparison of in vivo and in silico results

100%

Salem J. E., Cabrera M. E., Chandler M. P., McElfresh T. A., Huang H., Sterk J. P., Stanley W. C.

Journal of Physiology and Pharmacology

|

2004

|

tom 55

|

nr 3

This study tested the robustness of our computational model of myocardial metabolism by comparing responses to two different inputs with experimental data obtained in pigs under similar conditions. Accordingly, an abrupt and a gradual reduction in coronary flow of similar magnitude were implemented and used as model input. After flow reductions reached 60% from control values, ischemia was kept constant for 60 min in both groups. Our hypotheses were that: (1) these two flow-reduction profiles would result in different transients (concentrations and flux rates) while having similar steady-state values and (2) our model-simulated responses would predict the experimental results in an anesthetized swine model of myocardial ischemia. The two different ischemia-induction patterns resulted in the same decrease in steady-state MVO2 and in similar steady-state values for metabolite concentrations and flux rates at 60 min of ischemia. While both the simulated and experimental results showed decreased glycogen concentration, accumulation of lactate, and net lactate release with ischemia, the onset of glycogen depletion and the switch to lactate efflux were more rapid in the experiments than in the simulations. This study demonstrates the utility of computer models for predicting experimental outcomes in studies of metabolic regulation under physiological and pathological conditions.

3

Melatonin pretreatment does not modify extrasystolic burden in the rat ischemia-reperfusion model

84%

Durkina A. V., Bernikova O. G., Mikhaleva N. J., Paderin N. M., Sedova K. A., Gonotkov M. A., Kuzmin V. S., Azarov J. E.

Journal of Physiology and Pharmacology

|

2021

|

tom 72

|

nr 1

4

Effects of a bradycardic agent on postischemic cardiac recovery in rabbits

84%

Schmitz-Spanke S., Granetzny A., Stoffels B., Pomblum V. J., Gams E., Schipke J. D.

Journal of Physiology and Pharmacology

|

2004

|

tom 55

|

nr 4

Decreasing heart rate might be beneficial for improvement of myocardial energetics and could reduce the severity of myocardial ischemia. We examined the contribution of heart rate reduction by cilobradine (DK-AH 269), a direct sinus node inhibitor, on left ventricular function and peripheral vasomotion in anesthetized rabbits with experimental myocardial infarction. The rabbits were randomized to receive either placebo (n=10) or cilobradine (n=7). Cilobradine decreased significantly heart rate from 163 ± 33 to 131 ± 13 bpm, p< 0.05, without any inotopic or vascular effects. After 60 min coronary occlusion and 30 min reperfusion, both systolic and diastolic ventricular function were more reduced in the cilobradine group; i.e. maximal left ventricular pressure significantly decreased to 62 ± 11 mmHg, p < 0.05 (placebo: 77 ± 9 mmHg); dP/dtmin significantly decreased to -904 ± 247 mmHg, p < 0.05 (placebo: -1106 ± 242 mmHg). However, infarct size in the cilobradine group was significantly smaller compared with the placebo group. In conclusion, cilobradine reduced heart rate without any negative inotropic effect and reduced infarct size. On that account, this bradycardic agent might open a promising therapeutical avenue to treat postischemic dysfunction.

5

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Response of human blood platelet membrane to sodium selenite

84%

Zbikowska H. M., Gwozdzinski K., Wachowicz W., Krajewski T.

Journal of Physiology and Pharmacology

|

1999

|

tom 50

|

nr 3

6

Energetic state of the postischemic myocardium and its relation to contractile failure

84%

Andres J., Flameng W., Van Belle H.

Journal of Physiology and Pharmacology

|

1994

|

tom 45

|

nr 1

7

ATP-loaded liposomes and immunoliposomes protect ischemic myocardium in isolated rat hearts and in rabbits with experimental myocardial infarction

84%

Torchilin V. P., Verma D. D., Levchenko T. S., Hartner W. C., Bernstein E. A.

Cellular and Molecular Biology Letters

|

2005

|

tom 10

|

nr Suppl.

8

Permissive effect of molsidomine towards cardioprotective action of iloprost in myocardial ischaemia in cats

84%

Gryglewski R. J., Swies J., Chlopicki S., Niezabitowski P.

Journal of Physiology and Pharmacology

|

1993

|

tom 44

|

nr 3

9

Influence of diethylenetriamine [DETA] and sodium nitroprusside [NaNP] on sister chromatid exchange frequency and cell kinetics in cultured human lymphocytes

84%

Perkowska M., Szczygiel M., Wozniak A., Limon J.

Journal of Applied Genetics

|

2001

|

tom 42

|

nr 2

10

Human cytomegalovirus infection as a lifelong health problem

67%

Figlerowicz M., Modlinska-Cwalinska A., Mania A., Mazur-Melewska K., Kemnitz P., Jonczyk-Potoczna K., Sluzewski W.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

|

2011

|

tom 92

|

nr 4

11

The role of IL-1 in the pathogenesis of heart disease

67%

Bujak M., Frangogiannis N. G.

Archivum Immunologiae et Therapiae Experimentalis

|

2009

|

tom 57

|

nr 3

165-176

12

Myocardial bridging and coronary artery anomalies detected by ECG-gated 64-row multidetector computed tomography angiography in symptomatic patients

67%

Javadrashid R., Tarzamni M. K., Aslanabadi N., Ghaffari M., Salehi A., Sorteji K.

Folia Morphologica

|

2009

|

tom 68

|

nr 4

201-206

Advances in 64-row multidetector computed tomography have provided noninvasive imaging of coronary arteries. The aim of this study was to evaluate the prevalence of coronary artery anomalies in Iranian symptomatic patients and to determine the presence of anomalies resulting in myocardial ischaemia without atherosclerotic plaque. This study was carried out in Tabriz University of medical sciences on 534 patients with suggestive symptoms for coronary artery diseases. Original slices were reconstructed from data achieved by using a ECG-gated multidetector computed tomography scanner, and reconstructed 3-dimentional images of the heart were reviewed. Congenital angiography was performed in 36.3% of patients. The prevalence of myocardial bridging in symptomatic patients was 6.0% by multidetector computed tomography while conventional angiography could detect 20% of them. The most prevalent site was the middle portion of the left anterior descending artery. Anomalous origin or course of coronary arteries and AV fistula was detected by multidetector computed tomography coronary angiography in 2.6% of cases while conventional angiography could detect 44.4% of these anomalies. The prevalence of atherosclerotic plaques in patients with myocardial bridging was 53.1%. In 46.9% of these patients, myocardial bridging was held responsible for signs and symptoms of myocardial ischaemia as no atherosclerotic plaque was evident. This rate was 64.3% in symptomatic patients with other anomalies in origin or course of coronary arteries. This study gives the prevalence of coronary artery anomalies and myocardial bridging in the Iranian population. The results suggest multidetector computed tomography coronary angiography as the preferred utility for diagnosing such anomalies. (Folia Morphol 2009; 68, 4: 201–206)

13

Rola steroli i stanoli w leczeniu hipercholesterolemii i profilaktyce choroby niedokrwiennej serca

67%

Klosiewicz-Latoszek L., Ziolkowska A.

Bromatologia i Chemia Toksykologiczna

|

2002

|

tom 35

|

nr 4

395-402

14

Zachowania zywieniowe i masa ciala a natezenie cech osobowosci mezczyzn z niedokrwienna choroba serca

67%

Harton A., Narojek L., Solik-Tomassi A.

Bromatologia i Chemia Toksykologiczna

|

2008

|

tom 41

|

nr 3

690-694

15

Sprawozdanie z 53 Kongresu Polskiego Towarzystwa Kardiologicznego, Szczecin 7-8 pazdziernika 1993 r.

67%

Kozlowska-Wojciechowska M.

Biuletyn Informacyjny Instytutu Żywności i Żywienia

|

1993

|

tom 02

|

nr 4

10-11

16

Reperfusion after brief repetitive ischemia in porcine myocardium does not alter expression of creatine kinase MM or mitochondrial ATPase mRNAs1

67%

Andres J., Sharma H. S., Sassen L. M. A., Duncker D. J., Verdouw P. D., Schaper W.

Journal of Physiology and Pharmacology

|

1993

|

tom 44

|

nr 4

17

Kardiotoksycznosc tlenku wegla i ocena narazenia roznych grup zawodowych

59%

Lembas-Bogaczyk J., Dlugosz A., Gawron A., Milewska E.

Bromatologia i Chemia Toksykologiczna

|

2009

|

tom 42

|

nr 1

89-96

18

Izomery kwasow oleinowego i linolowego jako skladniki blaszki miazdzycowej

51%

Stachowska E., Dolegowska B., Chlubek D., Bober J., Gutowski P., Cnotliwy M., Trojnacka B.

Bromatologia i Chemia Toksykologiczna

|

2002

|

tom 35

|

nr 1

87-91

Zbadano zawartość izomerów trans kwasu oleinowego (C18:1), izomerów trans 9, trans 12 kwasu hnolowego (C18:2) oraz sprzęgniętych dienów kwasu linolowego (CLA) w blaszkach miażdżycowych tętnicy szyjnej pozyskanych śródoperacyjnie od pacjentów operowanych z powodu powikłań miażdżycy. Przeprowadzono analizę chromatograficzną 17 blaszek, stwierdzając w większości z nich obecność izomerów trans kwasu oleinowego i izomerów trans 9, trans 12 kwasu linolowego.

19

Spozycie witamin antyoksydacyjnych i ich surowiczy poziom u kobiet w wieku podeszlym z choroba niedokrwienna miesnia sercowego

43%

Duda G., Maruszewska M., Jozwiak A.

Bromatologia i Chemia Toksykologiczna

|

2005

|

tom 38

|

nr 1

13-18

W patologii zmian miażdżycowych poważną rolą odgrywa niedobór witamin antyoksydacyjnych. Podstawowym źródłem tych witamin powinny być spożywane racje pokarmowe. Celem przeprowadzonych badań było ustalenie na ile całodzienne racje pokarmowe kobiet w wieku podeszłym z chorobą niedokrwienną mięśnia sercowego pokrywają zapotrzebowanie na te witaminy oraz czy wielkość spożycia koreluje z ich surowiczym stężeniem? Stwierdzono niską żywieniową podaż witamin E, C oraz ß-karotenu w racjach pokarmowych chorych, która nie była statystycznie istotnie związana z ich surowiczym stężeniem.

Ograniczanie wyników

Respiratory burst of the neutrophils in ischemic heart disease patients

Step and ramp induction of myocardial ischemia: comparison of in vivo and in silico results

Melatonin pretreatment does not modify extrasystolic burden in the rat ischemia-reperfusion model

Effects of a bradycardic agent on postischemic cardiac recovery in rabbits

Response of human blood platelet membrane to sodium selenite

Energetic state of the postischemic myocardium and its relation to contractile failure

ATP-loaded liposomes and immunoliposomes protect ischemic myocardium in isolated rat hearts and in rabbits with experimental myocardial infarction

Permissive effect of molsidomine towards cardioprotective action of iloprost in myocardial ischaemia in cats

Influence of diethylenetriamine [DETA] and sodium nitroprusside [NaNP] on sister chromatid exchange frequency and cell kinetics in cultured human lymphocytes

Human cytomegalovirus infection as a lifelong health problem

The role of IL-1 in the pathogenesis of heart disease

Myocardial bridging and coronary artery anomalies detected by ECG-gated 64-row multidetector computed tomography angiography in symptomatic patients

Rola steroli i stanoli w leczeniu hipercholesterolemii i profilaktyce choroby niedokrwiennej serca

Zachowania zywieniowe i masa ciala a natezenie cech osobowosci mezczyzn z niedokrwienna choroba serca

Sprawozdanie z 53 Kongresu Polskiego Towarzystwa Kardiologicznego, Szczecin 7-8 pazdziernika 1993 r.

Reperfusion after brief repetitive ischemia in porcine myocardium does not alter expression of creatine kinase MM or mitochondrial ATPase mRNAs1

Kardiotoksycznosc tlenku wegla i ocena narazenia roznych grup zawodowych

Izomery kwasow oleinowego i linolowego jako skladniki blaszki miazdzycowej

Spozycie witamin antyoksydacyjnych i ich surowiczy poziom u kobiet w wieku podeszlym z choroba niedokrwienna miesnia sercowego