Wyniki wyszukiwania

1

Lymphatic vessels in the laryngeal mucosa - the glottis network

100%

Skarzynska B., Nowak M., Skarzynski H., Kukwa A.

Folia Morphologica

|

1988

|

tom 47

|

nr 1-4

2

Development of blood vessels of stomach wall in rabbits during prenatal period

88%

Jackowiak H., Godynicki S.

Folia Morphologica

|

1996

|

tom 55

|

nr 4

3

Regulation of gastrointestinal mucosal growth during aging

75%

Majumdar A. P. N.

Journal of Physiology and Pharmacology. Supplement

|

2003

|

tom 54

|

nr 4

143-154

The increase in the aging population has led to a growing interest in achieving a better understanding of the aging process and of diseases that are predominantly expressed during advancing age. Since the structural and, in turn, the functional integrity of the mucosa of the gastrointestinal tract (GI) are maintained by constant renewal of cells, a detailed knowledge of the events that initiate and regulate mucosal proliferative processes is essential for a better understanding of the normal aging process as well as age-associated dysfunctions, including malignancy that represent disorders of tissue growth. In Fischer-344 rats, aging is associated with increased mucosal proliferative activity in much of the GI tract. On the other hand, the functional properties are either decreased or remain unchanged during advancing age. Basal gastric acid and pepsin output decline during aging, as is gastrin secretion. In contrast, antral gastrin levels increase during this period, as is mucosal histidine decarboxylase activity. The age-related decline in gastrin secretion could partly be attributed to a higher ratio of somatostatin (D) to gastrin (G) cells in the antral mucosa. The age-related rise in GI mucosal proliferative activity could not be attributed to the trophic action of either gastrin or bombesin, since they caused no significant change in mucosal proliferation in aged rats. On the other hand, EGF and TGF-alphalpha appear to be involved in regulating mucosal proliferation during aging. Aging is associated with increased activation of EGF-receptor (EGFR), the common receptor for EGF and TGF-alpha. This could be due to (a) increased levels of membrane-bound precursor form(s) of TGF-alpha resulting in increased activation EGFR signaling processes through an autocrine/paracrine mechanism, (b) heightened sensitivity of mucosal EGFR to EGF and TGF-alpha such that comparatively lower levels of these peptides are required to activate EGFR in aged than in young animals and/or (c) loss of EGFR regulatory factor(s) such as ERRP (EGFR Related Protein), a "negative regulator" of EGFR.

4

Lymphatic net in the mucosa of the trachea and infraglottic area

75%

Skarzynski H., Skarzynska B., Kukwa A., Deszczynska H., Pagacz I.

Folia Morphologica

|

1988

|

tom 47

|

nr 1-4

5

The mucous membrane in areas devoid of papillae of the apex and body of the tongue in the silver fox [Vulpes vulpes fulva]

75%

Kulawik M., Sozanska M.

Acta Scientiarum Polonorum. Medicina Veterinaria

|

2007

|

tom 06

|

nr 2

6

Mucous membrane of the tongue in fetal development of the rabbit; preliminary studies

75%

Kulawik M., Jackowiak H., Godynicki S.

Folia Morphologica

|

1998

|

tom 57

|

nr 1

7

Cryopreserved tissue engineered mucosa

63%

Spoerl G., Mai R., Klingner E., Gedrange T., Lauer G.

Folia Histochemica et Cytobiologica

|

2008

|

tom 46

|

nr 4

541-544

8

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Mucosal vaccination - an old but still vital strategy

63%

Dlugonska H., Grzybowski M.

Annals of Parasitology

|

2012

|

tom 58

|

nr 1

The basic premise of vaccinology is to achieve strong protective immunity against defined infectious agents by a vaccine mimicking the effects of natural primary exposure to a pathogen. Because an exposure of humans and animals to microbes occurs mostly through mucosal surfaces, targeting the mucosa seems a rational and efficient vaccination strategy. Many experimental and clinical data confirmed that mucosal immunization offers many advantages over widely used in human and veterinary medicine subcutaneous or intramuscular immunization. In the present article selected aspects regarding mucosal vaccination are discussed. The structure and function of mucosaassociated lymphoid tissue (MALT), comprised of four main mucosal compartments forming a structural and functional unity as well as pivotal cellular MALT components (dendritic and M cells) were briefly characterized. Particular attention was focused on the mode of simple but efficacious delivery of vaccine antigens to mucosal surfaces. A few trials to generate potential mucosal vaccines against toxoplasmosis introduced by nasal or oral routes to experimental animals are also presented.

9

Tissue expression of S100 proteins in gallbladder mucosa of the patients with calculous cholecystitis

63%

Szmyt M., Kasprzak A., Malkowski W., Surdyk-Zasada J., Przybyszewska W., Siodla E., Seraszek-Jaros A., Jagielska J.

Folia Histochemica et Cytobiologica

|

2013

|

tom 51

|

nr 2

10

Changes in the lymphatic vessels network of the larynx caused by atrophy and hypertrophy of mucosa

63%

Skarzynski H., Skarzynska B., Kukwa A., Nowak M.

Folia Morphologica

|

1988

|

tom 47

|

nr 1-4

11

Quantitative histochemical analysis in pharmacological investigations

63%

Wisniewska I. E., Gawlik Z.

Folia Histochemica et Cytobiologica

|

1984

|

tom 22

|

nr 3-4

12

The role of mucus and its components in protection and repair within the alimentary tract mucosa: Polish experience

63%

Gindzienski A., Zwierz K., Sarosiek J.

Journal of Physiology and Pharmacology. Supplement

|

2003

|

tom 54

|

nr 3

127-144

The Gastroenterology Research Laboratory at New York Medical College, New York City, NY, directed by Prof. Dr. George B. Jerzy Glass and after his retirement by Prof. Dr. Bronislaw L. Slomiany and Prof. Dr. Amalia Slomiany served as a lunching pad for successful careers in exploration of mucus for Dr. Andrzej Gindzienski and Dr. Krzysztof Zwierz and Janusz Badurski at the Medical School in Bialystok, Poland as well as Dr. Jerzy Sarosiek at Gastroenterology Research Laboratory, University of Virginia Health Sciences Center, Charlottesville, VA and currently, Gastroenterology Research Laboratory, Kansas University Medical Center, Kansas City, KS, USA. The dynamic and insightful research endeavors implemented at the Medical School of Bialystok revealed new information regarding enzymatic pathways of mucin synthesis especially its carbohydrate components such as hexosamines. These discoveries become instrumental in our understanding of the alimentary tract mucin synthesis and function in health and disease. Similarly innovative mucus research conducted across the Atlantic Ocean uncovered the novelty of mucin elaborated within the esophageal submucosal mucous glands in humans by demonstration that its chemical characteristics are different both from human salivary and gastric mucins. In addition, a novel method for the measurement of the thickness of the gastric mucus layer ex vivo in humans has also been developed. These pioneering works are continued at both mucus exploration centers attracting younger generation of investigators enticed by the mystery of the structure and function of the mucus barrier and its leading role in mucosal protection against injury as well as immediate and unequivocal contribution to mucosal repair and reconstitution process.

13

Lymphatic tissue of mucosa in the respiratory system

63%

Dzialo J., Deptula W.

Advances in Agricultural Sciences

|

2010

|

tom 13

|

nr 1

14

The dimensions of the mucosa of the alimentary canal of Xenopus laevis [Daudin]

63%

Przystalski A., Wilczynska B.

Acta Universitatis Nicolai Copernici. Biologia

|

1995

|

tom 49[94]

15

Regulation of immunological mucosal tolerance

63%

Kraal G., Wolvers D. A. W.

Archivum Immunologiae et Therapiae Experimentalis. Supplement

|

2001

|

tom 49

|

nr 1

16

Relationship between ovarian cysts and changes in mucosa of the oviduct and uterus in sows

63%

Szulanczyk-Mencel K., Bielas W.

Bulletin of the Veterinary Institute in Puławy

|

2008

|

tom 52

|

nr 2

The aim of the study was a histological evaluation of mucosa of the oviduct and uterus, regarding cystic ovarian degeneration in sows. Materials for the evaluation were received after the slaughtering of 294 sows at the age of two to five years. The sows were eliminated from breeding and culled due to disorders such as: anoestrus after weaning of piglets, return of oestrus, small litter size, high number of parturitions, bad condition after lactation, and age. Twenty of the 294 sows (6.8%) had cysts on the ovaries. The sows were divided into two groups: group 1 (12 sows) with polycystic ovaries and group 2 (8 sows) with simple cysts, which occurred unilaterally (3 sows) or bilaterally (5 sows). The studies demonstrated different kinds of ovarian cysts and structural changes in ovarian cortex, such as decreasing number of ovarian follicles of all generations and increase in follicular atresia. The histological state of tissues and changes of mucosa of the oviduct and uterus, regarding polycystic ovaries or single cysts on ovaries were compared. The single follicular cysts were not accompanied with important changes in the reproductive system. In the case of polycystic ovaries, the presence of cyst was connected with the occurrence of morphological changes in the endothelium of the oviduct and uterus, which could have been a reason of persistent infertility in pigs. An increase in the number of secretory cells with simultaneous decrease in ciliated ones, both in the ampulla and isthmus and covering the epithelium by secretions were observed in the oviduct. In our studies, we observed increasing proliferation of both glandular epithelium and surface epithelium. The terminal portion of the uterine glands was cystic dilated with remaining secretions. Hypersecretion of superficial epithelium was noted.

17

Immunohistochemical localization of insulin-like growth factor-I receptors in the rat intestine

63%

Zik B., Yagci A., Altunbas K., Yakisik M.

Bulletin of the Veterinary Institute in Puławy

|

2006

|

tom 50

|

nr 2

18

Staphylococcus pseudintermedius, both commensal and pathogen

51%

Chrobak-Chmiel D., Golke A., Dembele K., Cwiek K., Kizerwetter-Swida M., Rzewuska M., Binek M.

Medycyna Weterynaryjna

|

2018

|

tom 74

|

nr 06

Staphylococcus pseudintermedius is considered to be a both commensal and opportunistic canine pathogen. The anal, perineal and nasal locations appear to be the main S. pseudintermedius colonization sites, from which bacteria are transmitted to other body sites, causing secondary infections. When the immune system is compromised because of an underlying condition, the skin becomes susceptible to infection. Thus, the host’s condition seems to play a crucial role in the pathogenesis of S. pseudintermedius infections. There are some predisposing factors, one of which is atopic dermatitis. The pathogenic effects of S. pseudintermedius are mediated by several virulence factors, for instance superantigens, which play an important role by causing dermatitis. The immune system has evolved many different mechanisms to recognize and deal with pathogens, but bacteria have also developed various strategies to evade them. In this review, we focus on early stages of the innate immune response with particular emphasis on the mechanisms of recognition of staphylococci and the action of antimicrobial peptides.

19

Development of the mucosa on lateral surfaces of the lingual body in the period from day 15 of prenatal life to 6th month of postnatal life in the rabbit

51%

Kulawik M.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

|

2006

|

tom 09

|

nr 2

Studies were conducted on 77 tongues, collected from rabbits being at day 15, 18, 20, 22 and 26 of prenatal life and from rabbits at day 1, 15 and 30 and in the 6th month of postnatal life. Tissues for analyses, collected from the lateral surfaces of the body of the tongue of rabbits, were studied under a light microscope (LM) and a scanning electron microscope (SEM). The thickness of the epithelium in successive periods of pre- and postnatal life was analyzed morphometrically. As a result of the conducted studies it was shown that the epithelium covering the lateral surfaces of the tongue changes in the course of pre- and postnatal development from an epithelium consisting from 1-2 layers of cells into a nonkeratinized stratified squamous epithelium. The thickness of the epithelium increases in successive analyzed periods of life in rabbits. A rapid growth rate was found for the epithelium in the period from day 26 p.c. The lamina propria mucosae is observed in histological slides starting from day 22 p.c. In the same period the presence of elastic fibers was shown. Glycogen was found in the cytoplasm of the epithelial and mesenchymal cells from day 15 to 20 p.c.

20

13C-urea breath test for detection of Helicobacter pylori and its correlation with endoscopic and histologic findings

51%

Hilker E., Domschke W., Stoll R.

Journal of Physiology and Pharmacology

|

1996

|

tom 47

|

nr 1

Ograniczanie wyników

Lymphatic vessels in the laryngeal mucosa - the glottis network

Development of blood vessels of stomach wall in rabbits during prenatal period

Regulation of gastrointestinal mucosal growth during aging

Lymphatic net in the mucosa of the trachea and infraglottic area

The mucous membrane in areas devoid of papillae of the apex and body of the tongue in the silver fox [Vulpes vulpes fulva]

Mucous membrane of the tongue in fetal development of the rabbit; preliminary studies

Cryopreserved tissue engineered mucosa

Mucosal vaccination - an old but still vital strategy

Tissue expression of S100 proteins in gallbladder mucosa of the patients with calculous cholecystitis

Changes in the lymphatic vessels network of the larynx caused by atrophy and hypertrophy of mucosa

Quantitative histochemical analysis in pharmacological investigations

The role of mucus and its components in protection and repair within the alimentary tract mucosa: Polish experience

Lymphatic tissue of mucosa in the respiratory system

The dimensions of the mucosa of the alimentary canal of Xenopus laevis [Daudin]

Regulation of immunological mucosal tolerance

Relationship between ovarian cysts and changes in mucosa of the oviduct and uterus in sows

Immunohistochemical localization of insulin-like growth factor-I receptors in the rat intestine

Staphylococcus pseudintermedius, both commensal and pathogen

Development of the mucosa on lateral surfaces of the lingual body in the period from day 15 of prenatal life to 6th month of postnatal life in the rabbit

13C-urea breath test for detection of Helicobacter pylori and its correlation with endoscopic and histologic findings