Znaleziono wyników: 3

Liczba wyników na stronie

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: monoaminergic system

Sortuj według:

Ogranicz wyniki do:

Involvement of the monoaminergic system in the antidepressant-like activity of chromium chloride in the forced swim test

100%

Piotrowska A., Siwek A., Wolak M., Pochwat B., Szewczyk B., Opoka W., Poleszak E., Nowak G.

Journal of Physiology and Pharmacology

2013

tom 64

nr 4

Propranolol modifies platelet serotonergic mechanisms in rats

100%

Zoltowski R., Pawlak R., Matys T., Pietraszek M., Buczko W.

Journal of Physiology and Pharmacology

2002

tom 53

nr 2

Though the mechanisms for the vascular actions of vasodilatory beta-blockers are mostly determined, some of their interactions with monoaminergic systems are not elucidated. Because there are evidences supporting a possible involvement of serotonin (5-HT) in the actions of beta-blockers, we studied the effect of propranolol on peripheral serotonergic mechanisms in normotensive and Goldblatt two-kidney - one clip (2K1C) hypertensive rats. In both groups of animals propranolol decreased systolic blood pressure, significantly increased whole blood serotonin concentration and at the same time it decreased platelet serotonin level. The uptake of the amine by platelets from hypertensive animals was lower than that of normotensive animals and it was decreased by propranolol only in the latter. In both groups propranolol inhibited potentiation of ADP - induced platelet aggregation by serotonin. In conclusion, this study provides evidence that propranolol modifies platelet serotonergic mechanisms in normotensive and renal hypertensive rats.

Bicuculline administration into ventromedial hypothalamus: effects on fear and regional brain monoamines and GABA concentrations in rats

80%

Zagrodzka J., Romaniuk A., Wieczorek M., Boguszewski P.

Acta Neurobiologiae Experimentalis

2000

tom 60

nr 3

Ograniczanie wyników

2 Journal of Physiology and Pharmacology

1 Acta Neurobiologiae Experimentalis

1 Boguszewski P.

1 Buczko W.

1 Matys T.

1 Nowak G.

1 Opoka W.

1 Pawlak R.

1 Pietraszek M.

1 Piotrowska A.

1 Pochwat B.

1 Poleszak E.

1 Romaniuk A.

1 Siwek A.

1 Szewczyk B.

1 Wieczorek M.

1 Wolak M.

1 Zagrodzka J.

1 Zoltowski R.

1 2013

1 2002

1 2000

Wyniki wyszukiwania

Involvement of the monoaminergic system in the antidepressant-like activity of chromium chloride in the forced swim test

Propranolol modifies platelet serotonergic mechanisms in rats

Bicuculline administration into ventromedial hypothalamus: effects on fear and regional brain monoamines and GABA concentrations in rats