Wyniki wyszukiwania

1

Computational studies on enzymatic phosphate hydrolysis

100%

Villa J.

Cellular and Molecular Biology Letters

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2003

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tom 08

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nr 2A

2

The putative role of cell adhesion molecules and N-Cam in particular in tumor formation and spreading

100%

Zeromski J.

Folia Histochemica et Cytobiologica. Supplement

|

2001

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tom 39

|

nr 1

3

Application in tumor therapy of cells engineered to express new biologically active molecules

100%

Jakobisiak M.

Folia Histochemica et Cytobiologica. Supplement

|

1997

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tom 35

|

nr 2

4

The IP vs. VDE competition as a key factor determining the stability of the MgBX5 (X = F, CL) compounds

86%

Sikorska C., Skurski P., Jaworski S.

Current Topics in Biophysics. Supplement

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2011

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tom 34

|

nr A: Posters

5

Application of characteristic volumes and topological indices of molecules in toxicity prediction of several anionic surfactants in aquatic environment

86%

Zielinski R.

Towaroznawcze Problemy Jakości. Polskie Towarzystwo Towaroznawcze

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2018

|

nr 2

6

Unitarne i pluralistyczne teorie przyrodoznawstwa na przykładzie teorii chemicznych

86%

Mierzecki R.

Analecta. Studia i Materiały z Dziejów Nauki

|

2016

|

tom 25

|

nr 2

7

Internalization of HLA class I molecules examined by use of mouse monoclonal antibodies in flow cytometry

86%

Pochron B., Gorka J., Kusnierczyk P.

Cellular and Molecular Biology Letters

|

2002

|

tom 07

|

nr Suppl.

8

The L1 family of neural cell adhesion molecules-linking cell adhesion to membrane skeleton organization

86%

Hortsch M., Dubreuil R. R.

Cellular and Molecular Biology Letters

|

1998

|

tom 03

|

nr 2

9

Dinucleoside polyphosphates - friend or foe ?

86%

McLennan A. G.

Cellular and Molecular Biology Letters

|

1999

|

tom 04

|

nr 3

10

Analysis of the structure - anticancer activity relationship in a set of Schiff bases of macrocyclic 2,6-bis[2- and 4-formylaryloxymethyl]pyridines

86%

Kuz'min V. E., Lozitsky V. P., Kamalov G. L., Lozitskaya R. N., Zheltvay A. I., Fedtchouk A. S., Kryzhanovsky D. N.

Acta Biochimica Polonica

|

2000

|

tom 47

|

nr 3

Quantitative estimation of the structure anticancer activity relationship in a series of macrocyclic Schiff bases of 2,6-bis(formylaryloxymethyl)pyridines was carried out by the topological approach. Correlation equations describing the relationship between the anticancer activity and structural parameters of the molecules studied and descriptors characterizing their structure were obtained on the basis of in vitro screening data. The influence of structure of the investigated substances as reflected by the parameters studied on the anticancer activity, was established.

11

Design, synthesis and biological evaluation of a new bridged immunosuppressor

86%

Szewczuk Z., Wilczynski A., Petry I., Siemion I. Z., Wieczorek Z.

Acta Biochimica Polonica

|

2001

|

tom 48

|

nr 4

A bridged peptide with the sequence: H-Thr-Pro-Gln-Arg-Gly-Asp-Val-y-Abu-Asn- Asp-Gln-Glu-Glu-Thr-Thr-Gly-Val-Val-Ser-Thr-Pro-Leu-Ile-Arg-Asn-Gly-OH was designed to mimic the discontinuous epitope of the HLA-DQ molecule that might interact with CD4. The bridged peptide revealed distinct suppressory effect in the humoral immune response. This result supports our suggestion that the 164-172 region of the HLA-DQ molecule may enhance its interactions with coreceptors, possibly with CD4.

12

Effect of trichostatin a on transcription of selected signal molecule genes in Jurkat T cells

86%

Januchowski R., Jagodzinski P. P.

Cellular and Molecular Biology Letters

|

2005

|

tom 10

|

nr Suppl.2

13

Viewing nuclear pore contraction with the atomic force microscope

86%

Rakowska A., Schneider S. W., Danker T., Schuricht B., Oberleithner H.

Cellular and Molecular Biology Letters

|

1997

|

tom 02

|

nr 2

14

37kDa oncofetal antigen is an autoimmunogenic homologue of the 37kDa laminin receptor precursor

86%

Barsoum A. L., Rohrer J. W., Coggin J. H.

Cellular and Molecular Biology Letters

|

2000

|

tom 05

|

nr 2

The laminin receptor precursor (LRP) has been the center of intense controversy and interest for over a decade. Chief among these controversies is the putative multifunctional aspect of this molecule: as a ribosomal-associated protein (p40) and/or as the precursor for the 67kDa high-affinity laminin receptor (67LR), neither of which have been definitively established. Other controversies include the presence of more than one 67kDa laminin receptor protein. However, interest in the molecule is sustained because of its vital function in the cell as a component of the translational machinery and due to its constant up-regulation in cancer cells with the invasive and metastatic phenotype and in association with poor prognosis. Recently, while studying the autoimmunogenicity of a species conserved 37-44 kDa oncofetal antigen (37kDa OFA), the authors of this paper, using amino acid sequencing of isolated OFA-peptides, cDNA cloning and sequencing and antigens-antibodies cross reactivity as well as antigens-T cell recognition reactions, identified the 37kDa OFA as precursor or immature laminin receptor protein.

15

Studies on incorporating small fluorescent molecules into pamam dendrimers

86%

Klajnert B., Bryszewska M.

Cellular and Molecular Biology Letters

|

2002

|

tom 07

|

nr 2

16

Myosin molecule packing within the vertebrate skeletal muscle thick filaments. A complete bipolar model

86%

Skubiszak L., Kowalczyk L.

Acta Biochimica Polonica

|

2002

|

tom 49

|

nr 4

Computer modelling related to the real dimensions of both the whole filament and the myosin molecule subfragments has revealed two alternative modes for myosin molecule packing which lead to the head disposition similar to that observed by EM on the surface of the cross-bridge zone of the relaxed vertebrate skeletal muscle thick filaments. One of the modes has been known for three decades and is usually incorporated into the so-called three-stranded model. The new mode differs from the former one in two aspects: (1) myosin heads are grouped into asymmetrical cross-bridge crowns instead of symmetrical ones; (2) not the whole myosin tail, but only a 43-nm C-terminus of each of them is straightened and near-parallel to the filament axis, the rest of the tail is twisted. Concurrent exploration of these alternative modes has revealed their influence on the filament features. The parameter values for the filament models as well as for the building units depicting the myosin molecule subfragments are verified by experimental data found in the literature. On the basis of the new mode for myosin molecule packing a complete bipolar structure of the thick filament is created.

17

Caryophyllidea [Cestoidea]: molecules, morphology and evolution

86%

Mackiewicz J. S.

Acta Parasitologica

|

2003

|

tom 48

|

nr 3

Recent literature on the evolution and interrelationships of the Caryophyllidea based on molecular and morphological criteria is reviewed. Molecular analyses with SSU rDNA, LSU rDNA and ef-1 alpha reaffirms the basal or near basal position of these nonozoic cestodes. Major emphasis is on an evaluation of the scoring in morphological character matrices used in cladistic studies. Suggested changes to present scoring are: uterus is dorsal; scolex is afossate, fossate or difossate with little support for monofossate; ciliated coracidium is absent; vitellaria are circum-cortical and circum-medullary; testes are cortical and medullary; metacercoid stage is absent; and the spermatozoan lacks a crested body, flagellar rotation and proximodistal fusion. Of the 41 recognized genera of the Caryophyllidea, 59% have an afossate scolex and the remainders are fossate. The use of a new character, “nuclear vacuole” in the nucleus of mature vitellocytes, is suggested. To aid in identifying cestode body types in an evolutionary context, they are designated as monopleuroid, polypleuroid and strobila. Tabulated differences between the monozoic Caryophyllidea and polyzoic eucestodes suggest that the two groups may warrant separate taxonomic status. The question of whether or not the monozoic state is primary or secondarily derived is not resolved. Using the life cycle characterstics of the Pseudophyllidea and of Archigetes as models, it is hypothesized that progenesis may have played a major role in the evolution of the Caryophyllidea. If the role of progenesis can be substantiated through total evidence incorporating cytohistological data, then the monozoic condition becomes coincidental and the hypothesis is not supported that the Caryophyllidea are ancestral and preceded polyzoic eucestodes.

18

Characterization of chosen products of combustion processes

72%

Szynkowska M. I., Pawlaczyk A., Rogowski J., Bawolak K., Paryjczak T.

Polish Journal of Environmental Studies

|

2008

|

tom 17

|

nr 3

411-419

The basic form of pollution is characterized by a microscopic size and solid state and it is called particulates or particulate matter. Unfortunately, these forms undergo a variety of transformations, which consequently can sometimes be easily modified and even cause an increase in their toxicity. This work was devoted to join the composition of various materials being residues after different combustion processes with the distribution of elements and molecules within studied surfaces. The content of chosen elements was determined using ICP-MS and ICP-OES methods. Elemental and/or molecular distribution was studied using surface sensitive techniques, SEM-EDS and ToF-SIMS. The obtained results revealed that the composition and morphology of particles are strongly influenced by the type of material and combustion conditions.

19

Syntaxin 8 has two functionally distinct di-leucine-based motifs

72%

Kasai K., Suga K., Izumi T., Akagawa K.

Cellular and Molecular Biology Letters

|

2008

|

tom 13

|

nr 1

144-154

Syntaxin 8 has been shown to form the SNARE complex with syntaxin 7, vti1b and endobrevin. These have been shown to function as the machinery for the homotypic fusion of late endosomes. Recently, we showed that syntaxins 7 and 8 cycle through the plasma membrane, and that the di-leucine-based motifs in the cytoplasmic domain of syntaxins 7 and 8 respectively function in their endocytic and exocytic processes. However, we could not elucidate the mechanism by which syntaxin 8 cycles through the plasma membrane. In this study, we constructed several different syntaxin 8 molecules by mutating putative di-leucine-based motifs, and analyzed their intracellular localization and trafficking. We found a di-leucine-based motif in the cytoplasmic domain of syntaxin 8. It is similar to that of syntaxin 7, and functions in its endocytosis. These results suggest that in the cytoplasmic domain, syntaxin 8 has two functionally distinct di-leucine-based motifs that act independently in its endocytic and exocytic processes. This is the first report on two di-leucine-based motifs in the same molecule acting independently in distinct transport pathways.

20

Distribution of poly(A)RNA and splicing machinery elements in mature pollen grains and in vitro growing pollen tubes of Hyacinthus orientalis L.

72%

Zienkiewicz K., Smolinski D. J., Bednarska E.

Acta Biologica Cracoviensia. Series Botanica. Supplement

|

2005

|

tom 47

|

nr 1

Ograniczanie wyników

Computational studies on enzymatic phosphate hydrolysis

The putative role of cell adhesion molecules and N-Cam in particular in tumor formation and spreading

Application in tumor therapy of cells engineered to express new biologically active molecules

The IP vs. VDE competition as a key factor determining the stability of the MgBX5 (X = F, CL) compounds

Application of characteristic volumes and topological indices of molecules in toxicity prediction of several anionic surfactants in aquatic environment

Unitarne i pluralistyczne teorie przyrodoznawstwa na przykładzie teorii chemicznych

Internalization of HLA class I molecules examined by use of mouse monoclonal antibodies in flow cytometry

The L1 family of neural cell adhesion molecules-linking cell adhesion to membrane skeleton organization

Dinucleoside polyphosphates - friend or foe ?

Analysis of the structure - anticancer activity relationship in a set of Schiff bases of macrocyclic 2,6-bis[2- and 4-formylaryloxymethyl]pyridines

Design, synthesis and biological evaluation of a new bridged immunosuppressor

Effect of trichostatin a on transcription of selected signal molecule genes in Jurkat T cells

Viewing nuclear pore contraction with the atomic force microscope

37kDa oncofetal antigen is an autoimmunogenic homologue of the 37kDa laminin receptor precursor

Studies on incorporating small fluorescent molecules into pamam dendrimers

Myosin molecule packing within the vertebrate skeletal muscle thick filaments. A complete bipolar model

Caryophyllidea [Cestoidea]: molecules, morphology and evolution

Characterization of chosen products of combustion processes

Syntaxin 8 has two functionally distinct di-leucine-based motifs

Distribution of poly(A)RNA and splicing machinery elements in mature pollen grains and in vitro growing pollen tubes of Hyacinthus orientalis L.