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1

A high frequency of apoptosis was found in cultures of lymphocytes isolated from the venous blood of children born with a low birth weight

100%
Barg E., Gasiorowski K., Brokos B., Swiedrych A., Skorkowska K.
Cellular and Molecular Biology Letters
|
2004
|
tom 09
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nr 1
Children born with a low birth weight (below 2500g) exhibit a slower rate of development, and a greater tendency towards morbidity and mortality, together with a deficit of weight and height. One reason could be an increase in the level of cell elimination by apoptosis. The aim of this study was to evaluate and compare the incidence of apoptotic and necrotic (dead) cells in cultures of peripheral blood lymphocytes obtained from children born with a low birth weight and from children with a normal birth weight. Peripheral blood lymphocytes were obtained by venipuncture (10 ml) and isolated using the density gradient centrifugation method. The lymphocytes were cultured for 48 h in a culture medium containing low concentrations of fetal calf serum. A comparison study was performed between low birth weight children and normal birth weight children and the susceptibility of their lymphocytes to apoptosis and to necrosis in serum-deficient feeding culture conditions. The amount of apoptotic cells and the percentage of dead cells were significantly higher in cultures of lymphocytes obtained from low birth weight children than in cultures from normal birth weight children. The two estimated parameters inversely correlated with the concentration of fetal calf serum in the culture medium. Pulsed field gel electrophoresis showed increased DNA degradation patterns in the cultures of lymphocytes obtained from low birth weight children. Our results should be perceived as an indication that, under worse feeding conditions, the elimination of cells by apoptosis and by necrosis is significantly higher for lymphocytes of low birth weight children than for those of normal birth weight children. The enhanced elimination of lymphocytes is related to a greater susceptibility to infections, especially of the respiratory tract, as established in the retrospective analysis of the anamneses of the examined group of low birth weight children.
2

Low birthweight as the best indicator of environmental disaster

86%
Norska-Borowka I., Bursa J., Kasznia-Kocot J.
Polish Journal of Environmental Studies
|
1996
|
tom 05
|
nr 4
The incidence of low birthweight was examined among 6794 newborns in 4 towns in the industrial region of Upper Silesian: Świętochłowice, Bytom, Zabrze and Chorzów. Ecological disaster has caused an increasing number of infants with birthweight below 2500 g in the most polluted towns. In Chorzów, in the most polluted part of the town, mean body weight decreased (3015g) in comparison with mean body weight in less polluted districts (3087 g and 3102 g). Low birthweight is one of the most important health indicators of a population affected by environmental pollution. The second negative impact connected with very high pollution is the high incidence of congenital defects and childrens' morbidity rate as the same as disturbed physical and psychological development.
3
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Study of the association of the nutritional profile of pregnant women with the birth weight of newborns in Morocco

72%
Elfane H., El-Jamal S., Sahe K., Mziwira M., El Ayachi M., Belahsen R.
Roczniki Państwowego Zakładu Higieny
|
2021
|
tom 72
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nr 4
4
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Application of the hypothesis of developmental origin of health and diseases (DOHaD) in epidemiological studies of women at reproductive age and pregnant women in Poland

58%
Wojtyla A.
Annals of Agricultural and Environmental Medicine
|
2011
|
tom 18
|
nr 2
5

Niezakaźne przyczyny sprzyjające przedodsadzeniowej śmiertelności prosiąt

30%
Czyzewska-Dors E., Dors A.
Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii
|
2018
|
tom 13
|
nr 2
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